Patents by Inventor Michael B. Murphy

Michael B. Murphy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240115804
    Abstract: A pump for pumping fluid includes a tube platen, a plunger, a bias member, inlet and outlet valves, an actuator mechanism, a position sensor, and a processor. The plunger is configured for actuation toward and away from the infusion-tube when the tube platen is disposed opposite to the plunger. The tube platen can hold an intravenous infusion tube. The bias member is configured to urge the plunger toward the tube platen.
    Type: Application
    Filed: October 10, 2023
    Publication date: April 11, 2024
    Inventors: Dean KAMEN, John M. Kerwin, Colin H. Murphy, Jonathan Parker, Daniel F. Pawlowski, Dirk A. Van Der Merwe, Larry B. Gray, Christopher C. Langenfeld, Michael S Place, Michael J. Slate
  • Publication number: 20220177593
    Abstract: Provided herein are compositions, methods and uses involving antibodies that specifically bind to Axl, a receptor tyrosine kinase. Also provided are uses and methods for managing, treating, or preventing disorders, such as cancer using the anti-Axl antibodies.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 9, 2022
    Applicant: Celldex Therapeutics, Inc.
    Inventors: Tibor Keler, Diego Alvarado, Richard W. Gedrich, Joel Goldstein, Laura Vitale, Thomas O'Neill, Andrea Crocker, Jenifer Widger, Michael B. Murphy, Shannon Pankratz
  • Patent number: 8105982
    Abstract: The present method is an improved in vitro selection protocol that relies on magnetic separations for DNA aptamer production that is relatively easy and scalable without the need for expensive robotics. The ability of aptamers selected by this method to recognize and bind their target protein with high affinity and specificity, and detail their uses in a number of assays is also described. Specific TTF1 and His6 aptamers were selected using the method described, and shown to be useful for enzyme-linked assays, Western blots, and affinity purification.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: January 31, 2012
    Assignee: The Regents of the University of California
    Inventors: Sharon A. Doyle, Michael B. Murphy
  • Publication number: 20100155349
    Abstract: A boxed caddy or pallet suitable for quick installation and removal on top of a rolling ice chest or similar hexahedral appliance, into to which goods can be piled for transportation to a beach or picnic site. The caddy folds flat for convenient storing into a car trunk. The multi-railed sides of the caddy are telescopically adjustable. Brackets projecting downwardly from the lower edges of the sides come to rest against the walls of the appliance, thus providing bi-directional horizontal stability. Adjustable stabilization straps can conveniently be secured between the caddy and appliance. The caddy has a removable top cover and can double as a small table.
    Type: Application
    Filed: December 19, 2008
    Publication date: June 24, 2010
    Inventor: Michael B. Murphy
  • Publication number: 20090075834
    Abstract: The present method is an improved in vitro selection protocol that relies on magnetic separations for DNA aptamer production that is relatively easy and scalable without the need for expensive robotics. The ability of aptamers selected by this method to recognize and bind their target protein with high affinity and specificity, and detail their uses in a number of assays is also described. Specific TTF1 and His6 aptamers were selected using the method described, and shown to be useful for enzyme-linked assays, Western blots, and affinity purification.
    Type: Application
    Filed: February 6, 2008
    Publication date: March 19, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Sharon A. Doyle, Michael B. Murphy
  • Patent number: 7329742
    Abstract: The present method is an improved in vitro selection protocol that relies on magnetic separations for DNA aptamer production that is relatively easy and scalable without the need for expensive robotics. The ability of aptamers selected by this method to recognize and bind their target protein with high affinity and specificity, and detail their uses in a number of assays is also described. Specific TTF1 and His6 aptamers were selected using the method described, and shown to be useful for enzyme-linked assays, Western blots, and affinity purification.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: February 12, 2008
    Assignee: The Regents of the University of California
    Inventors: Sharon A. Doyle, Michael B. Murphy
  • Patent number: 6640252
    Abstract: An apparatus and method for creating packages and for transferring packages between computer systems provides a graphical user interface that allows a user to define various attributes for a package. Logical packages may be defined, which specify package elements to include in the package. Physical packages may also be defined, which contain a copy of the package elements specified in the logical package. Once a user defines a logical package, the logical package may be transferred to an endpoint system. The endpoint system reads the logical package, and from the parameters in the logical package determines where to retrieve the package elements and what other actions are appropriate while retrieving the package elements and constructing a physical package. In this manner, the endpoint system retrieves the package elements as required. The preferred embodiment of the present invention defines a packager using an object oriented framework mechanism that defines both core and extensible functions.
    Type: Grant
    Filed: January 4, 2002
    Date of Patent: October 28, 2003
    Assignee: International Business Machines Corporation
    Inventors: Gregory Richard Hintermeister, Gregory S. Hurlebaus, Erik Duane Lindberg, Robert Anthony Mahlik, Michael B. Murphy
  • Patent number: 6428380
    Abstract: A model airplane includes a main body component, a wing component, a horizontal stabilizer component, and a vertical stabilizer component. At least some of the components are fabricated of a shell of lightweight wood with spaces therebetween. A sheet of lightweight plastic material covers each of the components. The material is wrapped around the components with an individual sheet for the components. The plastic material is lightweight with a thickness of between about 0.65 and 0.85 mils and has the ability when heated to contract to about 25 percent of its original size.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: August 6, 2002
    Inventor: Michael B. Murphy
  • Publication number: 20020065937
    Abstract: An apparatus and method for creating packages and for transferring packages between computer systems provides a graphical user interface that allows a user to define various attributes for a package. Logical packages may be defined, which specify package elements to include in the package. Physical packages may also be defined, which contain a copy of the package elements specified in the logical package. Once a user defines a logical package, the logical package may be transferred to an endpoint system. The endpoint system reads the logical package, and from the parameters in the logical package determines where to retrieve the package elements and what other actions are appropriate while retrieving the package elements and constructing a physical package. In this manner, the endpoint system retrieves the package elements as required. The preferred embodiment of the present invention defines a packager using an object oriented framework mechanism that defines both core and extensible functions.
    Type: Application
    Filed: January 4, 2002
    Publication date: May 30, 2002
    Applicant: International Business Machines Corporation
    Inventors: Gregory Richard Hintermeister, Gregory S. Hurlebaus, Erik Duane Lindberg, Robert Anthony Mahlik, Michael B. Murphy
  • Patent number: 6345306
    Abstract: An apparatus and method for creating packages and for transferring packages between computer systems provides a graphical user interface that allows a user to define various attributes for a package. Logical packages may be defined, which specify package elements to include in the package. Physical packages may also be defined, which contain a copy of the package elements specified in the logical package. Once a user defines a logical package, the logical package may be transferred to an endpoint system. The endpoint system reads the logical package, and from the parameters in the logical package determines where to retrieve the package elements and what other actions are appropriate while retrieving the package elements and constructing a physical package. In this manner, the endpoint system retrieves the package elements as required. The preferred embodiment of the present invention defines a packager using an object oriented framework mechanism that defines both core and extensible functions.
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: February 5, 2002
    Assignee: International Business Machines Corporation
    Inventors: Gregory Richard Hintermeister, Gregory S. Hurlebaus, Erik Duane Lindberg, Robert Anthony Mahlik, Michael B. Murphy