Patents by Inventor Michael B. Schultz

Michael B. Schultz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS OF PARP14 MODULATORS AND/OR MUTANTS AND THERAPEUTIC USE THEREOF
    Publication number: 20200407700
    Abstract: The invention provides compositions comprising agents which modulate poly(ADP-ribose)polymerase 14 (PARP14), or compositions comprising PARP14 mutants. Such compositions can modulate the levels of nicotinamide adenine dinucleotide (NAD+) and are useful in methods for treating or preventing cancer, aging, aging-related disorders, cell death, radiation damage, radiation exposure, disorders associated with inflammation, among others. Such compositions and methods may also improve DNA repair, cell proliferation, cell survival, modulate inflammatory response, among others, and may increase the life span of a cell or protect it against certain stresses, apoptosis, among others.
    Type: Application
    Filed: February 25, 2019
    Publication date: December 31, 2020
    Inventors: David A. Sinclair, Michael B. Schultz
  • PURIFICATION OF GERM STEM CELLS BY TARGETING MRP9
    Publication number: 20180002662
    Abstract: Provided herein are methods and compositions for the purification and detection of germ stem cells (e.g., oogonial stem cells) based on expression of MRP9.
    Type: Application
    Filed: January 12, 2016
    Publication date: January 4, 2018
    Applicant: President and Fellows of Harvard College
    Inventors: Michael B. Schultz, Michael S. Bonkowski, David A. Sinclair