Patents by Inventor Michael Badia

Michael Badia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gyrase inhibitors and uses thereof
    Patent number: 7414046
    Abstract: The present invention relates to compounds of the formula I: or a pharmaceutically acceptable derivative or prodrug thereof. The compounds are useful as inhibitors of bacterial gyrase activity. The present invention also relates to methods for treating bacterial infections in mammala. The present invention also relates to methods for decreasing bacterial quantity in a biological sample.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: August 19, 2008
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Anne-Laure Grillot, Paul Charifson, Dean Stamos, Yusheng Liao, Michael Badia, Martin Trudeau
  • Inhibitors of IMPDH enzyme
    Patent number: 7087642
    Abstract: The present invention relates to compounds which inhibit IMPDH. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH-mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
    Type: Grant
    Filed: November 4, 2002
    Date of Patent: August 8, 2006
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Dean Stamos, Martin Trudeau, Scott Bethiel, Steven Ronkin, Michael Badia, Jeffrey Saunders
  • Inhibitors of IMPDH enzyme
    Publication number: 20050282876
    Abstract: The present invention relates to a novel class of compounds which are IMPDH inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
    Type: Application
    Filed: July 29, 2005
    Publication date: December 22, 2005
    Inventors: David Armistead, Michael Badia, Guy Bemis, Randy Bethiel, Catharine Frank, Perry Novak, Steven Ronkin, Jeffrey Saunders
  • Gyrase inhibitors and uses thereof
    Patent number: 6930116
    Abstract: The present invention relates to compounds of the formula I: where Ring A is a thiazole, oxazole, imidazole or pyrazole and the substituents are as described in the specification, and pharmaceutically acceptable salts thereof. The compounds inhibit bacterial gyrase activity and therefore are useful for treating bacterial infections in mammals.
    Type: Grant
    Filed: March 24, 2003
    Date of Patent: August 16, 2005
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Paul Charifson, Dean Stamos, Michael Badia, Anne Laure Grillot, Steven Ronkin, Martin Trudeau
  • Inhibitors of IMPDH enzyme
    Publication number: 20050148644
    Abstract: The present invention relates to compounds which inhibit IMPDH. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH-mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
    Type: Application
    Filed: November 24, 2004
    Publication date: July 7, 2005
    Inventors: Dean Stamos, Martin Trudeau, Randy Bethiel, Steven Ronkin, Michael Badia, Jeffrey Saunders
  • Gyrase inhibitors and uses thereof
    Publication number: 20040043989
    Abstract: The present invention relates to compounds of the formula I: 1
    Type: Application
    Filed: May 23, 2003
    Publication date: March 4, 2004
    Inventors: Anne-Laure Grillot, Paul Charifson, Dean Stamos, Yusheng Liao, Michael Badia, Martin Trudeau
  • Inhibitors of IMPDH enzyme
    Publication number: 20040029939
    Abstract: The present invention relates to compounds which inhibit IMPDH. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH-mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
    Type: Application
    Filed: November 4, 2002
    Publication date: February 12, 2004
    Inventors: Dean Stamos, Martin Trudeau, Scott Bethiel, Steven Ronkin, Michael Badia, Jeffrey Saunders
  • Gyrase inhibitors and uses thereof
    Publication number: 20040024030
    Abstract: The present invention relates to compounds of the formula I: 1
    Type: Application
    Filed: March 24, 2003
    Publication date: February 5, 2004
    Inventors: Paul Charifson, Dean Stamos, Michael Badia, Anne Laure Grillot, Steven Ronkin, Martin Trudeau
  • Gyrase inhibitors and uses thereof
    Patent number: 6632809
    Abstract: The present invention relates to compounds of the formula I: or a pharmaceutically acceptable derivative or prodrug thereof. The compounds are useful as inhibitors of bacterial gyrase activity. The present invention also relates to methods for treating bacterial infections in mammala. The present invention also relates to methods for decreasing bacterial quantity in a biological sample.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: October 14, 2003
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Anne-Laure Grillot, Paul Charifson, Dean Stamos, Yusheng Liao, Michael Badia, Martin Trudeau
  • Gyrase inhibitors and uses thereof
    Publication number: 20030170858
    Abstract: Disclosed herein are compounds comprising the pharmacophore features HBA, HBD, Grp1, and at least two features selected from Grp2, Grp3 or Grp4: 1
    Type: Application
    Filed: July 18, 2002
    Publication date: September 11, 2003
    Inventors: Paul Charifson, Steve Bellon, Dean Stamos, Michael Badia, Anne-Laure Grillot, Steven Ronkin, Mark Murcko, Martin Trudeau
  • Gyrase inhibitors and uses thereof
    Patent number: 6608087
    Abstract: The present invention relates to compounds of the formula I: where Ring A is a thiazole, oxazole, imidazole or pyrazole and the substituents are as described in the specification, and pharmaceutically acceptable salts thereof. The compounds inhibit bacterial gyrase activity and therefore are useful for treating bacterial infections in mammals.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: August 19, 2003
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Paul Charifson, Dean Stamos, Michael Badia, Anne-Laure Grillot, Steven Ronkin, Martin Trudeau
  • Gyrase inhibitors and uses thereof
    Publication number: 20030119868
    Abstract: The present invention relates to compounds of the formula I: 1
    Type: Application
    Filed: December 12, 2001
    Publication date: June 26, 2003
    Inventors: Anne-Laure Grillot, Paul Charifson, Dean Stamos, Yusheng Liao, Michael Badia, Martin Trudeau
  • Inhibitors of IMPDH enzyme
    Patent number: 6498178
    Abstract: The present invention relates to compounds which inhibit IMPDH. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH-mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: December 24, 2002
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Dean Stamos, Martin Trudeau, Scott Bethiel, Steven Ronkin, Michael Badia, Jeffrey Saunders
  • Inhibitors of IMPDH enzyme
    Publication number: 20020111378
    Abstract: The present invention relates to compounds which inhibit IMPDH. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH-mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
    Type: Application
    Filed: September 19, 2001
    Publication date: August 15, 2002
    Inventors: Dean Stamos, Martin Trudeau, Scott Bethiel, Steven Ronkin, Michael Badia, Jeffrey Saunders