Patents by Inventor Michael Barish

Michael Barish has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DUAL-TARGETING CHIMERIC ANTIGEN RECEPTOR MODIFIED T CELLS COMPRISING IL-13 AND CHLOROTOXIN FOR CANCER TREATMENT
    Publication number: 20230374085
    Abstract: Chimeric antigen receptors having a chlorotoxin domain and an IL-13 are described. These dual targeted chimeric antigen receptors are useful for treating glioblastoma and other cancers of neuroectodermal origin.
    Type: Application
    Filed: March 11, 2021
    Publication date: November 23, 2023
    Inventors: Christine E. Brown, Dongrui Wang, Michael Barish, Stephen J. Forman
  • CHIMERIC ANTIGEN RECEPTORS CONTAINING A CHLOROTOXIN DOMAIN
    Publication number: 20220177528
    Abstract: Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.
    Type: Application
    Filed: November 5, 2021
    Publication date: June 9, 2022
    Inventors: Michael Barish, Christine E. Brown, Stephen J. Forman, Dongrui Wang
  • Chimeric antigen receptors containing a chlorotoxin domain
    Patent number: 11230577
    Abstract: Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: January 25, 2022
    Assignee: City of Hope
    Inventors: Michael Barish, Christine E. Brown, Stephen J. Forman, Dongrui Wang
  • CHIMERIC ANTIGEN RECEPTORS CONTAINING A CHLOROTOXIN DOMAIN
    Publication number: 20190389917
    Abstract: Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.
    Type: Application
    Filed: October 13, 2016
    Publication date: December 26, 2019
    Inventors: Michael Barish, Christine E. Brown, Stephen J. Forman, Dongrui Wang