Patents by Inventor Michael Bassler

Michael Bassler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140370612
    Abstract: A method and system for using spatially modulated excitation/emission and relative movement between a particle (cell, molecule, aerosol, . . . ) and an excitation/emission pattern are provided. In at least one form, an interference pattern of the excitation light with submicron periodicity perpendicular to the particle flow is used. As the particle moves along the pattern, emission is modulated according to the speed of the particle and the periodicity of the stripe pattern. A single detector, which records the emission over a couple of stripes, can be used. The signal is recorded with a fast detector read-out in order to capture the “blinking” of the particles while they are moving through the excitation pattern. This concept enables light detection with high signal-to-noise ratio and high spatial resolution without the need of expensive and bulky optics.
    Type: Application
    Filed: September 2, 2014
    Publication date: December 18, 2014
    Inventors: Michael Bassler, Peter Kiesel, Oliver Schmidt, Noble M. Johnson
  • Patent number: 8847855
    Abstract: An embodiment is a display unit. The display unit includes a substrate layer, a layer of colored fluid on the substrate layer, and a transparent actuator element on the layer of the colored fluid. The layer of colored fluid has a thickness and a color. The transparent actuator element modulates the thickness of the colored fluid upon activated by a force such that the colored fluid is changed from a first state to a second state or vice versa. The modulated thickness provides a variable optical density of the colored fluid.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: September 30, 2014
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Jurgen Hans Daniel, Michael Bassler
  • Patent number: 8821799
    Abstract: A method and system for using spatially modulated excitation/emission and relative movement between a particle (cell, molecule, aerosol, . . . ) and an excitation/emission pattern are provided. In at least one form, an interference pattern of the excitation light with submicron periodicity perpendicular to the particle flow is used. As the particle moves along the pattern, emission is modulated according to the speed of the particle and the periodicity of the stripe pattern. A single detector, which records the emission over a couple of stripes, can be used. The signal is recorded with a fast detector read-out in order to capture the “blinking” of the particles while they are moving through the excitation pattern. This concept enables light detection with high signal-to-noise ratio and high spatial resolution without the need of expensive and bulky optics.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: September 2, 2014
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Michael Bassler, Peter Kiesel, Oliver Schmidt, Noble M. Johnson
  • Patent number: 8816940
    Abstract: An embodiment is a display unit. The display unit includes a substrate layer, a layer of colored fluid on the substrate layer, and a transparent actuator element on the layer of the colored fluid. The layer of colored fluid has a thickness and a color. The transparent actuator element modulates the thickness of the colored fluid upon activated by a force such that the colored fluid is changed from a first state to a second state or vice versa. The modulated thickness provides a variable optical density of the colored fluid.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: August 26, 2014
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Jergens Hans Daniel, Michael Bassler
  • Publication number: 20140192359
    Abstract: A filter arrangement can transmit and/or reflect light emanating from a moving object so that the emanating light has time variation, and the time variation can include information about the object, such as its type. For example, emanating light from segments of a path can be transmitted/reflected through positions of a filter assembly, and the transmission functions of the positions can be sufficiently different that time variation occurs in the emanating light between segments. Or emanating light from a segment can be transmitted/reflected through a filter component in which simpler transmission functions are superimposed, so that time variation occurs in the emanating light in accordance with superposition of two simpler non-uniform transmission functions. Many filter arrangements could be used, e.g. the filter component could include the filter assembly, which can have one of the simpler non-uniform transmission functions.
    Type: Application
    Filed: January 14, 2014
    Publication date: July 10, 2014
    Inventors: Joerg Martini, Peter Kiesel, Malte Huck, Marshall W. Bern, Noble M. Johnson, Michael Bassler, Markus Beck
  • Patent number: 8723140
    Abstract: An analyzer includes a flow cell having a flow channel through which a sample passes. A light source excites at least a first particle type in the sample in one or more excitation region(s), and a detector detects light emitted by the excited particle. A spatial filter defines detection regions, wherein light emitted by the particle is transmitted to the detector, and interspersed shielded regions, wherein such light is at least partially blocked from reaching the detector. The light emitted by the excited particle has a response time ?1, and the sample may also contain a component that is excited by the light source and that has a response time ?2<?1. The excitation region(s) and the detection regions are arranged to provide a time delay between excitation and detection, the time delay tailored to isolate light emitted by the first particle from light emitted by the component.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: May 13, 2014
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Peter Kiesel, Richard H. Bruce, Michael Bassler
  • Patent number: 8629981
    Abstract: A filter arrangement can transmit and/or reflect light emanating from a moving object so that the emanating light has time variation, and the time variation can include information about the object, such as its type. For example, emanating light from segments of a path can be transmitted/reflected through positions of a filter assembly, and the transmission functions of the positions can be sufficiently different that time variation occurs in the emanating light between segments. Or emanating light from a segment can be transmitted/reflected through a filter component in which simpler transmission functions are superimposed, so that time variation occurs in the emanating light in accordance with superposition of two simpler non-uniform transmission functions. Many filter arrangements could be used, e.g. the filter component could include the filter assembly, which can have one of the simpler non-uniform transmission functions.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: January 14, 2014
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Joerg Martini, Peter Kiesel, Malte Huck, Marshall W. Bern, Noble M. Johnson, Michael Bassler, Markus Beck
  • Publication number: 20130278991
    Abstract: An embodiment is a display unit. The display unit includes a substrate layer, a layer of colored fluid on the substrate layer, and a transparent actuator element on the layer of the colored fluid. The layer of colored fluid has a thickness and a color. The transparent actuator element modulates the thickness of the colored fluid upon activated by a force such that the colored fluid is changed from a first state to a second state or vice versa. The modulated thickness provides a variable optical density of the colored fluid.
    Type: Application
    Filed: June 12, 2013
    Publication date: October 24, 2013
    Inventors: Jurgen Hans Daniel, Michael Bassler
  • Publication number: 20130100519
    Abstract: An embodiment is a display unit. The display unit includes a substrate layer, a layer of colored fluid on the substrate layer, and a transparent actuator element on the layer of the colored fluid. The layer of colored fluid has a thickness and a color. The transparent actuator element modulates the thickness of the colored fluid upon activated by a force such that the colored fluid is changed from a first state to a second state or vice versa. The modulated thickness provides a variable optical density of the colored fluid.
    Type: Application
    Filed: December 17, 2012
    Publication date: April 25, 2013
    Inventors: Jergens Hans Daniel, Michael Bassler
  • Publication number: 20130037728
    Abstract: An analyzer includes a flow cell having a flow channel through which a sample passes. A light source excites at least a first particle type in the sample in one or more excitation region(s), and a detector detects light emitted by the excited particle. A spatial filter defines detection regions, wherein light emitted by the particle is transmitted to the detector, and interspersed shielded regions, wherein such light is at least partially blocked from reaching the detector. The light emitted by the excited particle has a response time ?1, and the sample may also contain a component that is excited by the light source and that has a response time ?2<?1. The excitation region(s) and the detection regions are arranged to provide a time delay between excitation and detection, the time delay tailored to isolate light emitted by the first particle from light emitted by the component.
    Type: Application
    Filed: August 9, 2011
    Publication date: February 14, 2013
    Applicant: PALO ALTO RESEARCH CENTER INCORPORATED
    Inventors: Peter Kiesel, Richard H. Bruce, Michael Bassler
  • Patent number: 8373860
    Abstract: A filter arrangement can transmit and/or reflect light emanating from a moving object so that the emanating light has time variation, and the time variation can include information about the object, such as its type. For example, emanating light from segments of a path can be transmitted/reflected through positions of a filter assembly, and the transmission functions of the positions can be sufficiently different that time variation occurs in the emanating light between segments. Or emanating light from a segment can be transmitted/reflected through a filter component in which simpler transmission functions are superimposed, so that time variation occurs in the emanating light in accordance with superposition of two simpler non-uniform transmission functions. One or more mask arrangements can be configured to receive the emanating light and in response provide encoded emanating light.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: February 12, 2013
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Peter Kiesel, Markus Beck, Noble M. Johnson, Michael Bassler
  • Patent number: 8350782
    Abstract: An embodiment is a display unit. The display unit includes a substrate layer, a layer of colored fluid on the substrate layer, and a transparent actuator element on the layer of the colored fluid. The layer of colored fluid has a thickness and a color. The transparent actuator element modulates the thickness of the colored fluid upon activated by a force such that the colored fluid is changed from a first state to a second state or vice versa. The modulated thickness provides a variable optical density of the colored fluid.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: January 8, 2013
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Jurgen Hans Daniel, Michael Bassler
  • Patent number: 8320983
    Abstract: An implantable product such as an article, device, or system can include analyte and non-analyte containers in parts that can be operated as optical cavities. The product can also include fluidic components such as filter assemblies that control transfer of objects that affect or shift spectrum features or characteristics such as by shifting transmission mode peaks or reflection mode valleys, shifting phase, reducing maxima or contrast, or increasing intermediate intensity width such as full width half maximum (FWHM). Analyte, e.g. glucose molecules, can be predominantly included in a set of objects that transfer more rapidly into the analyte container than other objects, and can have a negligible or zero rate of transfer into the non-analyte container; objects that transfer more rapidly into the non-analyte container can include objects smaller than the analyte or molecules of a set of selected types, including, e.g., sodium chloride.
    Type: Grant
    Filed: December 17, 2007
    Date of Patent: November 27, 2012
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Joerg Martini, Jeffrey Roe, Peter Kiesel, Michael Bassler, Alan Bell, Richard H. Bruce, Noble M. Johnson
  • Patent number: 8263955
    Abstract: Sensors can be used to obtain encoded sensing results from objects that have nonuniform relative motion. A photosensor or impedance-based sensor, for example, can obtain sensing results from objects that have relative motion within a sensing region relative to the sensor, with the relative motion being, for example, periodically varying, randomly varying, chirp-varying, or modulated relative motion that completes at least one modulation cycle within the sensing region. Relative motion can be caused by varying objects' speed and/or direction or by controlling flow of fluid carrying objects, movement of a channel, movement of a support structure, movement of a sensor, and/or pattern movement. A fluidic implementation can include shaped channel wall parts and/or a displacement component causing time-varying lateral displacement.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: September 11, 2012
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Peter Kiesel, Markus Beck, Michael Bassler, Noble M. Johnson
  • Patent number: 8153949
    Abstract: In response to objects having relative motion within an encoding/sensing region relative to an encoder/sensor that, e.g., photosenses emanating light or performs impedance-based sensing, sensing results can indicate sensed time-varying waveforms with information about the objects, about their relative motion, about excitation characteristics, about environmental characteristics, and so forth. An encoder/sensor can include, for example, a non-periodic arrangement of sensing elements; a longitudinal sequence of sensing elements with a combined sensing pattern that approximates a superposition or scaled superposition of simpler sensing patterns; and/or IC-implemented sensing elements that include photosensing arrays on ICs and readout/combine circuitry that reads out photosensed quantities from cells in groups in accordance with cell-group sensing patterns and combines the readout photosensed quantities to obtain the sensing results.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: April 10, 2012
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Peter Kiesel, Joerg Martini, Michael Bassler, Markus Beck, Noble M. Johnson
  • Patent number: 8153950
    Abstract: An encoder/sensor can obtain sensing results from objects in an encoding/sensing region; a trigger detector can respond to objects in a trigger detection region, providing respective trigger signals; and a relative motion component can cause relative motion of objects into the trigger detection region, from it into the encoding/sensing region, and within the encoding/sensing region. In response to an object's trigger signal, control circuitry can cause the encoder/sensor and/or the relative motion component to operate so that the encoder/sensor obtains sensing results indicating a time-varying waveform and processing circuitry can obtain data from the sensing results indicating a time-varying waveform. The time-varying waveform can include information resulting from the relative motion within the encoding/sensing region. The encoder/sensor and trigger detector can be implemented, for example, with discrete components or as sets of cells in a photosensing array on an integrated circuit.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: April 10, 2012
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Peter Kiesel, Markus Beck, Joerg Martini, Michael Bassler, Noble M. Johnson
  • Patent number: 8120782
    Abstract: A tunable optical cavity can be tuned by relative movement between two reflection surfaces, such as by deforming elastomer spacers connected between mirrors or other light-reflective components that include the reflection surfaces. The optical cavity structure includes an analyte region in its light-transmissive region, and presence of analyte in the analyte region affects output light when the optical cavity is tuned to a set of positions. Electrodes that cause deformation of the spacers can also be used to capacitively sense the distance between them. Control circuitry that provides tuning signals can cause continuous movement across a range of positions, allowing continuous photosensing of analyte-affected output light by a detector.
    Type: Grant
    Filed: October 22, 2009
    Date of Patent: February 21, 2012
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Peter Kiesel, Oliver Schmidt, Michael Bassler, Uma Srinivasan
  • Patent number: 8040526
    Abstract: An implantable product includes an optical cavity structure with first and second parts, each of which can operate as an optical cavity. The first part includes a container with at least one opening through which bodily fluid can transfer between the container's interior and exterior when the product is implanted in a body. The second part includes a container that is closed and contains a reference fluid. The implantable product can also include one or both of a light source component and a photosensing component. Photosensed quantities from the first part's output light can be adjusted based on photosensed quantities from the second part's output light. Both parts can have their light interface surfaces aligned so that they both receive input light from a light source component and both provide output light to a photosensing component.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: October 18, 2011
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Peter Kiesel, Oliver Schmidt, Michael Bassler, Richard H. Bruce, Noble M. Johnson
  • Publication number: 20110222062
    Abstract: A filter arrangement can transmit and/or reflect light emanating from a moving object so that the emanating light has time variation, and the time variation can include information about the object, such as its type. For example, emanating light from segments of a path can be transmitted/reflected through positions of a filter assembly, and the transmission functions of the positions can be sufficiently different that time variation occurs in the emanating light between segments. Or emanating light from a segment can be transmitted/reflected through a filter component in which simpler transmission functions are superimposed, so that time variation occurs in the emanating light in accordance with superposition of two simpler non-uniform transmission functions. Many filter arrangements could be used, e.g. the filter component could include the filter assembly, which can have one of the simpler non-uniform transmission functions.
    Type: Application
    Filed: May 20, 2011
    Publication date: September 15, 2011
    Applicant: PALO ALTO RESEARCH CENTER INCORPORATED
    Inventors: Joerg Martini, Peter Kiesel, Malte Huck, Marshall Bern, Noble M. Johnson, Michael Bassler, Markus Beck
  • Patent number: 7936463
    Abstract: A device can include both a photosensing component and an optical cavity structure, with the optical cavity structure including a part that can operate as an optical cavity in response to input light, providing laterally varying output light. For example, the optical cavity can be a graded linearly varying filter (LVF) or other inhomogeneous optical cavity, and the photosensing component can have a photosensitive surface that receives its output light without it passing through another optical component, thus avoiding loss of information. The optical cavity part can include a region that can contain analyte. Presence of the analyte affects the optical cavity part's output light, and the photosensing component can respond to the output light, providing sensing results indicating the analyte's optical characteristics.
    Type: Grant
    Filed: February 5, 2007
    Date of Patent: May 3, 2011
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Peter Kiesel, Oliver Schmidt, Michael Bassler