Abstract: A compartmentalized hydraulic fracturing (frac) system may include a mono line configured to carry frac fluid into a well. The system may include a plurality of zones, each zone comprising: a set of one or more frac pumps each configured to pump frac fluid into the mono line, an isolation valve configured to control the flow of frac fluid between the set of frac pumps and the mono line; and a bleed valve configured to release pressurized frac fluid from the set of frac pumps when in an open position. The system may include partition walls between the plurality of zones. The system may include a control system configured to deactivate or reactivate a zone of the plurality of zones by controlling the set of frac pumps, the isolation valve, and the bleed valve of the zone.

Abstract: A compartmentalized hydraulic fracturing (frac) system may include a mono line configured to carry frac fluid into a well. The system may include a plurality of zones, each zone comprising: a set of one or more frac pumps each configured to pump frac fluid into the mono line, an isolation valve configured to control the flow of frac fluid between the set of frac pumps and the mono line; and a bleed valve configured to release pressurized frac fluid from the set of frac pumps when in an open position. The system may include partition walls between the plurality of zones. The system may include a control system configured to deactivate or reactivate a zone of the plurality of zones by controlling the set of frac pumps, the isolation valve, and the bleed valve of the zone.

Abstract: In one aspect, an implant removal device for removal of ruptured silicone breast implants includes a hollow container having a middle portion disposed between a first end and a second end. The device also has a connector port coupled to the second end that is coupled to a suction device during use. The device also includes a nozzle coupled to the first end that is configured for placement against an incision of a patient for removing a ruptured breast implant from the patient. The middle portion of the hollow container defines one or more vent holes extending between an interior and exterior container surface with the one or more vent holes configured to reduce negative pressure within the hollow container when the suction device is activated during the removal process.

Abstract: Stented prosthetic heart valves comprising a stent frame having a compressed arrangement for delivery within a patient's vasculature and an expanded arrangement for deployment within a native heart valve. The stented prosthetic heart valves including a paravalvular leakage prevention or mitigation wrap that encircles a stent frame and is formed of a flexible material having a variable diameter defined by a greatest distance between the wrap and the stent frame. The wrap further includes a first end coupled to the stent frame and an opposing second end that is not coupled to the stent frame, wherein the wrap can selectively enlarge its diameter in situ via movement of the second end. Devices for and methods of selectively deploying the wrap are also disclosed.

Abstract: Aspects of the disclosure relate to devices and methods for preparing an existing, implanted prosthetic aortic valve for subsequent prosthetic aortic valve implantation. To prepare the existing valve, a valve preparation device is delivered to the valve and valve leaflets are severed either via mechanical cutting or electrodes so that the leaflets cannot obstruct a blood flow path once a prosthetic valve is subsequently implanted within the valve. Similarly, in alternate embodiments, devices and methods of the disclosure can be used for preparing a native aortic valve for delivery and implantation of a prosthetic valve.

Abstract: An implant removal device for removal of ruptured silicone breast implants includes a hollow container having a middle portion disposed between a first end and a second end. The device also has a connector port coupled to the second end that is coupled to a suction device during use. The device also includes a nozzle coupled to the first end that is configured for placement against an incision of a patient for removing a ruptured breast implant from the patient. The positioning of the nozzle on said first end is offset from a longitudinal axis that extends in a direction parallel to the length of the middle portion and within the middle portion. The nozzle opening may include gripping portions for aiding in gripping the implant shell during the removal process.

Abstract: Aspects of the disclosure relate to devices and methods for preparing an existing, implanted prosthetic aortic valve for subsequent prosthetic aortic valve implantation. To prepare the existing valve, a valve preparation device is delivered to the valve and valve leaflets are severed either via mechanical cutting or electrodes so that the leaflets cannot obstruct a blood flow path once a prosthetic valve is subsequently implanted within the valve. Similarly, in alternate embodiments, devices and methods of the disclosure can be used for preparing a native aortic valve for delivery and implantation of a prosthetic valve.

Abstract: Transcatheter delivery systems, delivery catheters and associated methods for percutaneous delivery of prosthetic mitral valves using a retrograde approach are disclosed herein. A heart valve delivery system configured in accordance herewith includes a delivery catheter having an elongated tubular component and an articulation assembly at a distal end thereof. The articulation assembly includes an arm portion coupled to the tubular component by an elbow or hinge portion. In a closed, delivery state, the elbow portion positions the arm portion generally parallel to the tubular component for delivery of the delivery catheter through the vasculature. In an open, deployed state, the elbow portion positions the arm portion in a non-axial direction with respect to a longitudinal axis of the tubular component for orienting and positioning a prosthetic valve device carried by the arm portion, e.g., within the native mitral valve region.

Abstract: Delivery systems (100, 200, 300, 400, 500) including a delivery device (130, 230, 330, 430, 530) having a catheter (132, 133, 232, 233, 332, 333, 432, 433, 532) and a stabilization device (150, 250, 350, 450, 550), the delivery device configured for delivering an apparatus to a left atrium (20) of a patient via the patient's vasculature. The stabilization device has a delivery position in which the stabilization device is collapsed against the catheter and a deployed position in which the stabilization device expands to engage and support the catheter within the vasculature, for example, within the vena cava (14) proximate the right atrium (16). In various embodiments, the delivery device functions as an introducer though which a second delivery device carrying the apparatus is inserted. Methods of accessing the left atrium with the delivery systems and devices are also disclosed.

Abstract: Stented prosthetic heart valves comprising a stent frame having a compressed arrangement for delivery within a patient's vasculature and an expanded arrangement for deployment within a native heart valve. The stented prosthetic heart valves including a paravalvular leakage prevention or mitigation wrap that encircles a stent frame and is formed of a flexible material having a variable diameter defined by a greatest distance between the wrap and the stent frame. The wrap further includes a first end coupled to the stent frame and an opposing second end that is not coupled to the stent frame, wherein the wrap can selectively enlarge its diameter in situ via movement of the second end. Devices for and methods of selectively deploying the wrap are also disclosed.

Abstract: Stented prosthetic heart valves comprising a stent frame having a compressed arrangement for delivery within a patient's vasculature and an expanded arrangement for deployment within a native heart valve. The stented prosthetic heart valves including a paravalvular leakage prevention or mitigation wrap that encircles a stent frame and is formed of a flexible material having a variable diameter defined by a greatest distance between the wrap and the stent frame. The wrap further includes a first end coupled to the stent frame and an opposing second end that is not coupled to the stent frame, wherein the wrap can selectively enlarge its diameter in situ via movement of the second end. Devices for and methods of selectively deploying the wrap are also disclosed.

Abstract: Transcatheter delivery systems, delivery catheters and associated methods for percutaneous delivery of prosthetic mitral valves using a retrograde approach are disclosed herein. A heart valve delivery system configured in accordance herewith includes a delivery catheter having an elongated tubular component and an articulation assembly at a distal end thereof. The articulation assembly includes an arm portion coupled to the tubular component by an elbow or hinge portion. In a closed, delivery state, the elbow portion positions the arm portion generally parallel to the tubular component for delivery of the delivery catheter through the vasculature. In an open, deployed state, the elbow portion positions the arm portion in a non-axial direction with respect to a longitudinal axis of the tubular component for orienting and positioning a prosthetic valve device carried by the arm portion, e.g., within the native mitral valve region.

Abstract: An implant removal device for removal of ruptured silicone breast implants includes a hollow container having a middle portion disposed between a first end and a second end. The device also has a connector port coupled to the second end that is coupled to a suction device during use. The device also includes a nozzle coupled to the first end that is configured for placement against an incision of a patient for removing a ruptured breast implant from the patient. The positioning of the nozzle on said first end is offset from a longitudinal axis that extends in a direction parallel to the length of the middle portion and within the middle portion. The nozzle opening may include gripping portions for aiding in gripping the implant shell during the removal process.

Abstract: Transcatheter delivery systems, delivery catheters and associated methods for percutaneous delivery of prosthetic mitral valves using a retrograde approach are disclosed herein. A heart valve delivery system configured in accordance herewith includes a delivery catheter having an elongated tubular component and an articulation assembly at a distal end thereof. The articulation assembly includes an arm portion coupled to the tubular component by an elbow or hinge portion. In a closed, delivery state, the elbow portion positions the arm portion generally parallel to the tubular component for delivery of the delivery catheter through the vasculature. In an open, deployed state, the elbow portion positions the arm portion in a non-axial direction with respect to a longitudinal axis of the tubular component for orienting and positioning a prosthetic valve device carried by the arm portion, e.g., within the native mitral valve region.

Abstract: A system and a method that utilizes wet proppants when creating fracturing fluid by receiving wet fracturing sand at a surge tank, vibrating the wet fracturing sand located within the surge tank, liquefying the wet fracturing sand within the surge tank based on the vibration, and metering the liquefied wet fracturing sand from the surge tank to a blending tub.

Abstract: Aspects of the disclosure relate to devices and methods for preparing an existing, implanted prosthetic aortic valve for subsequent prosthetic aortic valve implantation. To prepare the existing valve, a valve preparation device is delivered to the valve and valve leaflets are severed either via mechanical cutting or electrodes so that the leaflets cannot obstruct a blood flow path once a prosthetic valve is subsequently implanted within the valve. Similarly, in alternate embodiments, devices and methods of the disclosure can be used for preparing a native aortic valve for delivery and implantation of a prosthetic valve.

Abstract: A system and a method for producing fracturing fluid, comprising: receiving source fluid from one or more inlet manifolds of a single transport, driving a first pump mounted on the single transport to route the source fluid from the inlet manifolds into a hydration tank mounted on the single transport, driving a second pump mounted on the single transport to route hydrated fluid produced by the hydration tank to a blending tub mounted on the single transport, and discharging fracturing fluid produced by the blending tub to one or more outlet manifolds of the single transport.

Abstract: A system and a method that utilizes wet proppants when creating fracturing fluid by receiving wet fracturing sand at a surge tank, vibrating the wet fracturing sand located within the surge tank, liquefying the wet fracturing sand within the surge tank based on the vibration, and metering the liquefied wet fracturing sand from the surge tank to a blending tub.