Patents by Inventor Michael Berbaum

Michael Berbaum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF PRODUCING COLLAGENASE
    Publication number: 20240110171
    Abstract: The present invention relates to the fields of collagenase production and collagenase products, and particularly to improving the reproducibility, purity, and stability of collagenase I and collagenase II compositions, where the compositions are pure to at least 95% by area as measured by reverse phase high pressure liquid chromatography (RP-HPLC) and essentially free of neutral protease.
    Type: Application
    Filed: February 15, 2023
    Publication date: April 4, 2024
    Inventors: Christine A. Sheaffer, Michael Berbaum, John Hanna, Jason Dziadosz, Daniel Shanafelt
  • Method of producing collagenase
    Patent number: 11473074
    Abstract: The present invention relates to the fields of collagenase production and collagenase products, and particularly to improving the reproducibility, purity, and stability of collagenase I and collagenase II compositions, where the compositions are pure to at least 95% by area as measured by reverse phase high pressure liquid chromatography (RP-HPLC) and essentially free of neutral protease.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: October 18, 2022
    Assignee: Endo Global Aesthetics Limited
    Inventors: Christine A. Sheaffer, Michael Berbaum, John Hanna, Jason Dziadosz, Daniel Shanafelt
  • METHOD OF PRODUCING COLLAGENASE
    Publication number: 20220119791
    Abstract: The present invention relates to the fields of collagenase production and collagenase products, and particularly to improving the reproducibility, purity, and stability of collagenase I and collagenase II compositions, where the compositions are pure to at least 95% by area as measured by reverse phase high pressure liquid chromatography (RP-HPLC) and essentially free of neutral protease.
    Type: Application
    Filed: December 22, 2021
    Publication date: April 21, 2022
    Inventors: Christine A. Sheaffer, Michael Berbaum, John Hanna, Jason Dziadosz, Daniel Shanafelt
  • METHOD OF PRODUCING COLLAGENASE
    Publication number: 20180327731
    Abstract: The present invention relates to the fields of collagenase production and collagenase products, and particularly to improving the reproducibility, purity, and stability of collagenase I and collagenase II compositions, where the compositions are pure to at least 95% by area as measured by reverse phase high pressure liquid chromatography (RP-HPLC) and essentially free of neutral protease.
    Type: Application
    Filed: March 28, 2018
    Publication date: November 15, 2018
    Inventors: Christine A. Sheaffer, Michael Berbaum, John Hanna, Jason Dziadosz, Daniel Shanafelt
  • Production of high molecular weight hyaluronates
    Patent number: 7002007
    Abstract: Methods of making high molecular weight hyaluronates are disclosed. The methods include contacting a hyaluronate-containing source with an acid to make an acidic hyaluronate suspension, contacting that suspension with an anionic ion exchange medium in the presence of an acidic buffer, and thereafter contacting the medium with an acidic buffer having a higher salt content to desorb the hyaluronate from the medium. The methods are amenable for isolating hyaluronate from such sources as avian (e.g., chicken, duck, turkey, or goose) eggshells and connective tissues of animals.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: February 21, 2006
    Assignee: Calcigen Corporation
    Inventor: Michael Berbaum
  • PRODUCTION OF HIGH MOLECULAR WEIGHT HYALURONATES
    Publication number: 20050267301
    Abstract: Methods of making high molecular weight hyaluronates are disclosed. The methods include contacting a hyaluronate-containing source with an acid to make an acidic hyaluronate suspension, contacting that suspension with an anionic ion exchange medium in the presence of an acidic buffer, and thereafter contacting the medium with an acidic buffer having a higher salt content to desorb the hyaluronate from the medium. The methods are amenable for isolating hyaluronate from such sources as avian (e.g., chicken, duck, turkey, or goose) eggshells and connective tissues of animals.
    Type: Application
    Filed: May 28, 2004
    Publication date: December 1, 2005
    Applicant: Calcigen Corporation
    Inventor: Michael Berbaum