Patents by Inventor Michael Binkley

Michael Binkley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132245
    Abstract: A plastic container includes a base, an opening, and a plurality of panels. In embodiments, the plurality of panels are configured for digital printing. Systems and methods for digital printing on plastic containers with a plurality of panels are also disclosed.
    Type: Application
    Filed: October 18, 2023
    Publication date: April 25, 2024
    Inventors: Kyle Fleischhacker, Andrew Fischer, Michael Sainato, Griffin Binkley
  • Publication number: 20210239591
    Abstract: Disclosed herein is are methods for isolating mammalian cells under continuous flow conditions, enriching mammalian cells under continuous flow conditions, and enriching microorganisms under continuous flow conditions. The methods include providing and loading a plurality of mammalian cells or microorganisms into an acoustic separation device. The acoustic separation device includes: an inlet; an outlet; a channel coupled to the inlet and the outlet, wherein the channel defines a flow path between the inlet and the outlet; a standing acoustic wave generating device; and at least one pillar array comprising a plurality of pillars, wherein the at least one pillar array is situated within the flow path defined by the channel, wherein the at least one pillar array includes a first pillar array and a second pillar array, wherein the first pillar array is substantially parallel to the second pillar array, wherein the first pillar array and the second pillar array form an enrichment structure.
    Type: Application
    Filed: April 5, 2021
    Publication date: August 5, 2021
    Applicant: WASHINGTON UNIVERSITY
    Inventors: Mikhail Y. Berezin, John Mark Meacham, Michael Binkley
  • Patent number: 10969324
    Abstract: An acoustic separation device for reagent manipulation a standing acoustic including a wave generating device and pairs of perforated pseudo walls comprising a longitudinal standing bulk acoustic wave (LSBAW) channel. The LSBAW channel provides local pressure field amplification to overcome drag forces arising from reagent flow. Further, method for manipulating a reagent under continuous flow conditions microcarrier particles locally confined in an acoustic separation device comprising an inlet and an outlet, a fluid routing layer coupled to a channel, a plurality of loading wells configured to hold a plurality of substances required for a desired synthesis, and a controller configured to distribute the plurality of substances held by the loading wells in a desired sequence. The device for antibody manipulation further comprises an ultrasound actuator, and a channel wherein the channel is separated from the ultrasound actuator.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: April 6, 2021
    Assignee: Washington University
    Inventors: Mikhail Berezin, John Mark Meacham, Michael Binkley
  • Patent number: 10807029
    Abstract: Disclosed herein are devices and methods of high throughput separation. A device comprises a reservoir for receiving a fluid in a flow direction and a transducer for generating a pressure field that is not perpendicular to the flow direction of the fluid through the reservoir. A method comprises receiving a fluid in a flow direction into a reservoir comprising an array of openings on at least one side of the channel or reservoir, generating a pressure field that is not perpendicular to the flow of the fluid through the reservoir, wherein at least one node and at least one antinode of the pressure field are within the reservoir, and separating the plurality of objects within the fluid, wherein at least a first object is retained within the reservoir and at least a second object is passed from the reservoir through the array of openings.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: October 20, 2020
    Assignee: WASHINGTON UNIVERSITY
    Inventors: John Mark Meacham, Michael Binkley, Andrei G. Fedorov, Fahrettin Levent Degertekin, Courtney Swadley
  • Publication number: 20190076769
    Abstract: Disclosed herein are devices and methods of high throughput separation. A device comprises a reservoir for receiving a fluid in a flow direction and a transducer for generating a pressure field that is not perpendicular to the flow direction of the fluid through the reservoir. A method comprises receiving a fluid in a flow direction into a reservoir comprising an array of openings on at least one side of the channel or reservoir, generating a pressure field that is not perpendicular to the flow of the fluid through the reservoir, wherein at least one node and at least one antinode of the pressure field are within the reservoir, and separating the plurality of objects within the fluid, wherein at least a first object is retained within the reservoir and at least a second object is passed from the reservoir through the array of openings.
    Type: Application
    Filed: March 15, 2017
    Publication date: March 14, 2019
    Inventors: John Mark Meacham, Michael Binkley, Andrei G. Fedorov, Fahrettin Levent Degertekin, Courtney Swadley
  • Publication number: 20190056302
    Abstract: An acoustic separation device for reagent manipulation a standing acoustic including a wave generating device and pairs of perforated pseudo walls comprising a longitudinal standing bulk acoustic wave (LSBAW) channel. The LSBAW channel provides local pressure field amplification to overcome drag forces arising from reagent flow. Further, method for manipulating a reagent under continuous flow conditions microcarrier particles locally confined in an acoustic separation device comprising an inlet and an outlet, a fluid routing layer coupled to a channel, a plurality of loading wells configured to hold a plurality of substances required for a desired synthesis, and a controller configured to distribute the plurality of substances held by the loading wells in a desired sequence. The device for antibody manipulation further comprises an ultrasound actuator, and a channel wherein the channel is separated from the ultrasound actuator.
    Type: Application
    Filed: August 16, 2018
    Publication date: February 21, 2019
    Applicant: WASHINGTON UNIVERSITY
    Inventors: Mikhail Berezin, John Mark Meacham, Michael Binkley