Abstract: An optical system for responding to distortions in incident light in a free space optical communication system includes a machine learning output storing at least an indication of multiple images and corresponding positioning or orientation attributes for one or more optical elements; a sensor configured to generate an image; and a component configured to adjust the one or more optical elements based on the generated image. Various other methods, systems, and apparatuses are also disclosed.

Abstract: A control system for an industrial automation facility and a method for programming and operating the control system use a program for the control system which is developed with a development tool. Data from a web server built into the control system is transmitted to a computer which is connected to the control system via a network. The data includes a web-based development environment. A representation of the development environment in a web browser is embodied on the computer. A program for the control system is developed or processed by a user. The program developed and/or processed by the user is converted into a high-level language program by a conversion module embodied in the web browser. The high-level language program is transmitted to the control system and converted into a binary program inside the control system. The binary program is implemented by the control system.

Abstract: An optical transceiver for controlling a steering angle between a receive light beam and a transmit light beam includes an optical beam coupling device. The optical beam coupling device comprises a plurality of optical elements configured to control a steering angle between the receive light beam received by the optical beam coupling device along a first line of sight (LOS) and the transmit light beam that is output from the optical beam coupling device along a second LOS different from the first LOS, wherein both the receive light beam and the transmit light beam pass through the plurality of optical elements. The plurality of optical elements have a set of combinations for different positions of each of the optical elements, wherein each position in the set of combinations induces a different steering angle between the transmit light beam and the receive light beam.

Abstract: Disclosed herein are compositions of retroviruses and methods of using the same for gene delivery, wherein the retroviruses comprise a viral envelope protein comprising at least one mutation that diminishes its native function, a non-viral membrane-bound protein comprising a membrane-bound domain and an extracellular targeting domain.

Abstract: Provided herein are chimeric antigen receptor (CAR) viral libraries and methods of making the same. In some embodiments, the CAR comprises an intracellular domain (ICD) with at least one immune activation signaling domain, one co-stimulatory domain, and one or more inhibitory signaling domain or signaling domain from non-T cell lineages. In some embodiments, the signaling domains of the ICD are joined by distinct linkers of 10 amino acids. In some embodiments, the CARs contain a 18-nucleotide barcode in the 3? untranslated region. Also provided herein, are CAR cell libraries and methods of making the same.

Abstract: A system for active co-boresight measurement includes a detector, first and second steering mirrors, and a controller. The detector detects a portion of a transmission beam emitted by a transmitter and a portion of a received beam received from a remote terminal. The controller instructs the first steering mirror to scan the detected portion of the received beam to determine an alignment position. The controller controls a position of the first steering mirror to align the portion of the received beam with the alignment position on the detector, and controls a position of the second steering mirror to align the detected portion of the transmission beam with a defined position on the detector. The detected portion of the received beam at the alignment position and the detected portion of the transmission beam at the defined position correspond to the received beam and the transmission beam being aligned.

Abstract: Method and Apparatus for Triggering the Automatic Generation of Narratives Artificial intelligence methods and systems for triggering the generation of narratives are disclosed. Specific embodiments relate to real-time evaluation and automated generation of narrative stories based on received data. For example, data can be tested against data representative of a plurality of story angles to determine whether a narrative story incorporating one or more such story angles is to be automatically generated.

Abstract: An optical system for responding to distortions in incident light in a free space optical communication system includes a machine learning output storing at least an indication of multiple images and corresponding positioning or orientation attributes for one or more optical elements; a sensor configured to generate an image; and a component configured to adjust the one or more optical elements based on the generated image. Various other methods, systems, and apparatuses are also disclosed.

Abstract: Artificial intelligence methods and systems for triggering the generation of narratives are disclosed. Specific embodiments relate to real-time evaluation and automated generation of narrative stories based on received data. For example, data can be tested against data representative of a plurality of story angles to determine whether a narrative story incorporating one or more such story angles is to be automatically generated.

Abstract: A control system for an industrial automation facility and a method for programming and operating the control system use a program for the control system which is developed with a development tool. Data from a web server built into the control system is transmitted to a computer which is connected to the control system via a network. The data includes a web-based development environment. A representation of the development environment in a web browser is embodied on the computer. A program for the control system is developed or processed by a user. The program developed and/or processed by the user is converted into a high-level language program by a conversion module embodied in the web browser. The high-level language program is transmitted to the control system and converted into a binary program inside the control system. The binary program is implemented by the control system.

Abstract: Selective chelation of bismuth radionuclide ions from a mixture including actinium radionuclide ions involves exposing a ligand to an aqueous solution that includes bismuth radionuclide ions and actinium radionuclide ions under conditions whereby the bismuth radionuclide ions selectively chelate to the ligand for form cationic complexes of the bismuth radionuclide ions. and separating the cationic complexes of the bismuth radionuclide ions from the actinium radionuclide ions. The ligands have a structure based on a 12-membered cyclen ring and may include pendant functional groups that can be derivatized with biological targeting vectors for targeted alpha therapy.

Abstract: A compact system for active co-boresight measurement includes a detector, a steering mirror, and a controller. The detector detects a portion of a transmission beam emitted by a transceiver and a portion of a received beam that is received from a remote terminal. The controller measures an offset between the detected portion of the received beam and the detected portion of the transmission beam. The controller controls a position of the steering mirror to align the portion of the received beam with a defined position on the detector, the defined position based in part on the offset.

Abstract: Systems and methods for optical communication through air or space are disclosed. A method includes encoding one or more data frames with a data-link layer forward error correction (FEC) code to produce a plurality of encoded data frames and transmitting the plurality of encoded data frames from a transmitter (TX) to a receiver (RX) at least partially through air or space using a plurality of optical beams. The RX identifies a corrupted encoded data frame and reconstructs the corrupted encoded data frame using a data-link layer FEC decoder operating over a plurality of non-corrupted encoded data frames.

Abstract: Optical systems and methods for transmission of multiple beams and direct detection of those beams are described. One transmitter for use in a free space optical communication system includes a broad spectrum light source and an optical component including a plurality of sections positioned to receive an optical beam produced by the broad spectrum light source. The sections of the optical component are formed to introduce optical path differences into portions of the optical beam that impinge on the optical component such that each section introduces a delay into a corresponding portion of the optical beam. The introduced delays cause each portion of the optical beam to lack coherence with other portions of the optical beam. A direct detection receiver detects the intensity of the aggregate beams and produces a signal with improved signal-to-noise ratio. The disclosed technology can be used with modulated optical beams such as intensity modulated beams.

Abstract: An optical system for responding to distortions in incident light in a free space optical communication system comprises a machine learning output storing at least an indication of multiple images and corresponding positioning or orientation attributes for one or more optical elements; a sensor configured to generate an image; and a component configured to adjust the one or more optical elements based on the generated image.

Abstract: An optical transceiver for controlling a steering angle between a receive light beam and a transmit light beam includes an optical beam coupling device. The optical beam coupling device comprises a plurality of optical elements configured to control a steering angle between the receive light beam received by the optical beam coupling device along a first line of sight (LOS) and the transmit light beam that is output from the optical beam coupling device along a second LOS different from the first LOS, wherein both the receive light beam and the transmit light beam pass through the plurality of optical elements. The plurality of optical elements have a set of combinations for different positions of each of the optical elements, wherein each position in the set of combinations induces a different steering angle between the transmit light beam and the receive light beam.

Abstract: A system for active co-boresight measurement includes a detector, first and second steering mirrors, and a controller. The detector detects a portion of a transmission beam emitted by a transmitter and a portion of a received beam received from a remote terminal. The controller instructs the first steering mirror to scan the detected portion of the received beam to determine an alignment position. The controller controls a position of the first steering mirror to align the portion of the received beam with the alignment position on the detector, and controls a position of the second steering mirror to align the detected portion of the transmission beam with a defined position on the detector. The detected portion of the received beam at the alignment position and the detected portion of the transmission beam at the defined position correspond to the received beam and the transmission beam being aligned.

Abstract: A compact system for active co-boresight measurement includes a detector, a steering mirror, and a controller. The detector detects a portion of a transmission beam emitted by a transceiver and a portion of a received beam that is received from a remote terminal. The controller measures an offset between the detected portion of the received beam and the detected portion of the transmission beam. The controller controls a position of the steering mirror to align the portion of the received beam with a defined position on the detector, the defined position based in part on the offset.

Abstract: Optical communication systems and methods using coherently combined optical beams are disclosed. A representative system includes a first mirror having a first actuator for adjusting a position of the first mirror in a path of a first optical beam and a first optical detector for receiving light reflected from the first mirror. The system also includes a second mirror having a second actuator for adjusting a position of the second mirror in a path of a second optical beam and a second optical detector for receiving light reflected from the second mirror. The system includes an interferometer for measuring an interference between the first and second optical beams and a third optical detector for receiving light from the second interfered optical beam. Intensity of the first interfered optical beam is increased by the interference, and intensity of the second interfered optical beam is decreased by the interference.

Abstract: Optical systems and methods for transmission of multiple beams and direct detection of those beams are described. One transmitter for use in a free space optical communication system includes a broad spectrum light source and an optical component including a plurality of sections positioned to receive an optical beam produced by the broad spectrum light source. The sections of the optical component are formed to introduce optical path differences into portions of the optical beam that impinge on the optical component such that each section introduces a delay into a corresponding portion of the optical beam. The introduced delays cause each portion of the optical beam to lack coherence with other portions of the optical beam. A direct detection receiver detects the intensity of the aggregate beams and produces a signal with improved signal-to-noise ratio. The disclosed technology can be used with modulated optical beams such as intensity modulated beams.