Abstract: Aryl piperidine compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, bipolar disorder), cancers and eye conditions: wherein X, R2a, R2b, R3, R4, R5a and R5b are as defined herein.

Abstract: A cleaning apparatus for a meat cutting band saw having a blade with a cutting flight portion and a return flight portion parallel to each other in which a water delivery manifold extends between the two flights and opposite ends are provided with nozzle assemblies having a pair of nozzles acting at an angle downwardly and against opposed sides of the blade to wash away meat and bone fragments while the saw is in its cutting mode. The cleaning apparatus includes flexible tubular hoses which lend themselves to easy fitting of the apparatus to existing saws.