Patents by Inventor Michael Blume

Michael Blume has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12222349
    Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: February 11, 2025
    Assignee: Seer, Inc.
    Inventors: Hongwei Xia, Lyndal Hesterberg, Michael Figa, Xiaoyan Zhao, Gregory Troiano, William Manning, John Blume, Omid Farokhzad, Matthew McLean, Craig Stolarczyk, Marwin Ko, Theodore Platt
  • Publication number: 20200057887
    Abstract: Methods and systems by which an identifier of a social event, attendee recognition data, and an image of an attendee are obtained. In some variants a portion of image data associated with the attendee recognition data is sent to a mobile client device in response both to a recipient authorization and to an image data selection identifying the portion of the image data.
    Type: Application
    Filed: November 7, 2017
    Publication date: February 20, 2020
    Applicant: LEYEFE, INC.
    Inventor: Michael BLUME
  • Patent number: 6774375
    Abstract: In a method for forming, with the aid of an electron beam (6), a polyline on a substrate (4) coated with a radiation-sensitive resist, the electron beam (6) is directed onto a surface of the substrate (4) in the direction of a Z coordinate, and the substrate (4) is displaced relative to the electron beam (6) in an X-Y plane in individual steps. After each individual step of the displacement, the electron beam (6) acts with a predefined energy input on the substrate (4) during a halt in the displacement motion. The energy input for each individual step is determined as a function of the shape of the polyline ascertained from several preceding individual steps. Also described is a corresponding apparatus with which, using electron beam lithography, it is possible to form polylines with a very uniform line width. The method and apparatus are particularly suitable for writing curved polylines.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: August 10, 2004
    Assignee: Leica Microsystems Lithography GmbH
    Inventors: Rainer Plontke, Andreas Schubert, Michael Blume, Ines Stolberg
  • Patent number: 6635884
    Abstract: The invention refers to the field of electron beam lithography, in particular to a method for directing an electron beam (6) onto a target position (Z) on the surface of a substrate, the substrate first being placed onto a movable stage (2) and the stage (2) then being displaced stepwise, in the X and/or Y coordinates of a Cartesian grid, until the target position (Z) is located at a spacing from the impact point (P) of the undeflected electron beam (6) which is smaller than the smallest step distance of the stage displacement system, and then the electron beam (6) is directed onto the target position (Z) by deflection. This results in a considerable increase in positioning accuracy in electron beam lithography. Positioning accuracies on the order of 0.1 nm to 0.05 are achievable. The method is suitable in particular for writing grating patterns in which the spacing between the individual grating lines must be maintained with high accuracy.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: October 21, 2003
    Assignee: Leica Microsystems Lithography GmbH
    Inventors: Rainer Plontke, Ines Stolberg, Michael Blume, Rainer Kaebsch, Matthias Zierbock
  • Publication number: 20010040221
    Abstract: In a method for forming, with the aid of an electron beam (6), a polyline on a substrate (4) coated with a radiation-sensitive resist, the electron beam (6) is directed onto a surface of the substrate (4) in the direction of a Z coordinate, and the substrate (4) is displaced relative to the electron beam (6) in an X-Y plane in individual steps. After each individual step of the displacement, the electron beam (6) acts with a predefined energy input on the substrate (4) during a halt in the displacement motion.
    Type: Application
    Filed: March 5, 2001
    Publication date: November 15, 2001
    Inventors: Rainer Plontke, Andreas Schubert, Michael Blume, Ines Stolberg
  • Publication number: 20010028039
    Abstract: The invention refers to the field of electron beam lithography, in particular to a method for directing an electron beam (6) onto a target position (Z) on the surface of a substrate, the substrate first being placed onto a movable stage (2) and the stage (2) then being displaced stepwise, in the X and/or Y coordinates of a Cartesian grid, until the target position (Z) is located at a spacing from the impact point (P) of the undeflected electron beam (6) which is smaller than the smallest step distance of the stage displacement system, and then the electron beam (6) is directed onto the target position (Z) by deflection.
    Type: Application
    Filed: March 5, 2001
    Publication date: October 11, 2001
    Inventors: Rainer Plontke, Ines Stolberg, Michael Blume, Rainer Kabsch, Matthias Zierbock
  • Patent number: 5219233
    Abstract: A process for controlling the operation of a printing head detects defects in the transport of the printing head along a printed line and if necessary corrects them. A control unit (24) controls a current source (16) which supplies current to a transport motor (12) which moves the printing head (10). The printing elements (14) of the printing head (10) are supplied with pulsed drive current (ID) by a driver component (18). A position indicator (20) records the distance travelled by the printing head (10) along a printed line. According to the invention, the transport time between two printing positions is monitored to detect whether a limit value (G) is exceeded. If the limit value (G) is exceeded, the drive of the printing head (10) is stopped and if necessary the printing head is moved in the opposite direction and/or at least one printing element (14, 15) is operated with less energy that that required for printing.
    Type: Grant
    Filed: September 11, 1991
    Date of Patent: June 15, 1993
    Assignee: Siemens Nixdorf Informationssysteme AG
    Inventors: Ralph Bauerle, Dietmar Kottwitz, Michael Blume, Joachim Schwarzkopf