Patents by Inventor Michael Bosch

Michael Bosch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-[(ARYLMETHYL)AMINOMETHYL]PIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
    Publication number: 20100240670
    Abstract: The invention relates to 4-[(arylmethyl)aminomethyl]piperidine derivatives of general formula (I) in the form of a base or an addition salt with an acid, and also in the form of a hydrate or solvate, and their preparation process and therapeutic application.
    Type: Application
    Filed: January 26, 2010
    Publication date: September 23, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Michael BOSCH, Jean WAGNON
  • NEW 2,4-DIANILINOPYRIMIDINES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF ESSENTIALLY AS IKK INHIBITORS
    Publication number: 20100035907
    Abstract: The disclosure relates to a compound of formula (I): wherein R1, R2, R3, R4, R5, A and Y are as defined in the specification, to compositions containing them, to processes for preparing them, and to their use in the treatment or prevention of conditions capable of being modulated by the inhibition of the activity of protein kinases.
    Type: Application
    Filed: July 1, 2009
    Publication date: February 11, 2010
    Applicant: Sanofi-aventis
    Inventors: Monsif BOUABOULA, Michael BOSCH, Pierre CASELLAS, Jean-Flaubert Nguefack, Bernard Tonnerre, Jean Wagnon
  • 4-[(arylmethyl)aminomethyl]piperidine derivatives, their preparation and their therapeutic application
    Patent number: 7652011
    Abstract: The invention relates to 4-[(arylmethyl)aminomethyl]piperidine derivatives of general formula (I) in the form of a base or an addition salt with an acid, and also in the form of a hydrate or solvate, and their preparation process and therapeutic application.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: January 26, 2010
    Assignee: sanofi-aventis
    Inventors: Michael Bosch, Jean Wagnon
  • Novel 2,4-Dianilinopyrimidine Derivatives, the Preparation Thereof, Their Use as Medicaments, Pharmaceutical Compositions and, in Particular, as IKK Inhibitors
    Publication number: 20080269170
    Abstract: The disclosure relates to compounds of formula (I): wherein R1-R5, A and Y are as defined in the disclosure, to compositions comprising said compounds, and to processes for making and methods of using the same.
    Type: Application
    Filed: January 9, 2008
    Publication date: October 30, 2008
    Applicant: sanofi-aventis
    Inventors: Michael Bosch, Monsif Bouaboula, Pierre Casellas, Samir Jegham, Serge Mignani, Jean-Flaubert Nguefack, Jacob-Alsboek Olsen, Bernard Tonnerre, Jean Wagnon
  • 4-[(ARYLMETHYL)AMINOMETHYL]PIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
    Publication number: 20070037819
    Abstract: The invention relates to 4-[(arylmethyl)aminomethyl]piperidine derivatives of general formula (I) in the form of a base or an addition salt with an acid, and also in the form of a hydrate or solvate, and their preparation process and therapeutic application.
    Type: Application
    Filed: May 26, 2006
    Publication date: February 15, 2007
    Applicant: sanofi-aventis
    Inventors: Michael Bosch, Jean Wagnon
  • Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof
    Publication number: 20060167007
    Abstract: The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; R1 represents a halogen atom; a trifluoromethyl radical; a (C1-C4) alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical; R2 represents a hydrogen atom or a halogen atom; R3 represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17; or else R3 constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring; R4 represents the aromatic group 1,3-thiazol-2-yl of formula: Preparation process and therapeutic application.
    Type: Application
    Filed: June 5, 2003
    Publication date: July 27, 2006
    Applicant: sanofi-aventis
    Inventors: Francoise Bono, Michael Bosch, Victor Dos Santos, Jean-Marc Herbert, Dino Nisato, Bernard Tonnerre, Jean Wagnon
  • Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof
    Publication number: 20050176722
    Abstract: The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; p is 1 or 2; R1 represents a halogen atom; a trifluoromethyl radical; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical; R2 represents a hydrogen atom or a halogen atom; R3 represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17; or else R3 constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring; R4 represents an aromatic group selected from: the said aromatic groups being unsubstituted or being mono- or disubstituted by a substituent selected independently from a halogen atom; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethyl radical; Preparation process and therapeutic application.
    Type: Application
    Filed: June 5, 2003
    Publication date: August 11, 2005
    Applicant: sanofi-aventis
    Inventors: Francoise Bono, Michael Bosch, Victor Dos Santos, Jean-Marc Herbert, Dino Nisato, Bernard Tonnerre, Jean Wagnon