Abstract: A method includes converting, by a generative network, an input into a latent vector representation of a sample chemical compound, wherein the input is one of an order-dependent representation of the sample chemical compound and a molecular graph representation of the sample chemical compound; determining, by an output neural network, one or more properties of the sample chemical compound based on the latent vector representation of the sample chemical compound; performing, by the output neural network, an optimization routine to select a candidate latent vector representation from among a plurality of latent vector representations based on the latent vector representation of the sample chemical compound, wherein the plurality of latent vector representations includes the latent vector representation of the sample chemical compound; and identifying, by the output neural network, a candidate chemical compound based on the candidate latent vector representation.

Abstract: Systems and methods use deep, convolutional neural networks over exponentially long history windows to learn alphabets for context tree weighting (CTW) for prediction. Known issues of depth and breadth in conventional context tree weighting predictions are addressed by the systems and methods. To deal with depth, the history can be broken into time windows, permitting the ability to look exponentially far back while having less information the further one looks back. To deal with breadth, a deep neural network classifier can be used to learn to map arbitrary length histories to a small output symbol alphabet. The sequence of symbols produced by such a classifier over the history windows would then become the input sequence to CTW.

Abstract: The invention disclosed herewith is a computer-implemented method for evaluating the toxicity of chemical compounds. In particular, some embodiments of the invention comprise importing microarray data representing measurements of the RNA transcription from hepatocytes, and running at least one algorithm (such as a coefficient penalized linear regression algorithm) on the imported data to assess potential adverse drug effects. After the evaluation has been carried out, the results are exported to reports or databases. In some embodiments of the invention, the algorithm has been trained on reference data using machine learning techniques. In some embodiments of the invention, the evaluation of toxicity is carried out concurrently with the evaluation of efficacy, where it can be used to assess the clinical value of the compounds evaluated. In some embodiments of the invention, the evaluation of toxicity is inserted into a pharmaceutical evaluation process prior to expensive testing of toxicity in animals.

Abstract: A method of treating wastewater sources such as sewer systems or those from pulp and paper mills which contain biomass waste involves adding white rot fungi in the presence of glucose. While glucose may be directly added to the wastewater source, it has been found to be more economical to reduce or substantially remove color from the wastewater by additionally adding brown rot fungi in the presence of cellulose and hemi-cellulose. The addition of bacteria has also been found helpful to improve the reduction in color, biological oxygen demand, as well as chemical oxygen demand in wastewater sludge reduction.

Abstract: A method of treating wastewater sources such as those from pulp and paper mills which contain lignin involves adding white rot fungi in the presence of glucose. While glucose may be directly added to the wastewater source, it has been found to be more economical to reduce or substantially remove color from the wastewater by additionally adding brown rot fungi in the presence of cellulose and hemi-cellulose. The addition of bacteria has also been found helpful to improve the reduction in color, biological oxygen demand, as well as chemical oxygen demand in wastewater.

Abstract: A coating system (66, 68), winding system (158), finishing system (274, 276) and manufacturing system (FIGS. 6, 7, 22-29) is provided for spiral-wound fluted filter media (74, 130).

Abstract: A container arrangement including a box, a removable lid, a hinge connecting the lid and the box, and a latch mechanism. The hinge construction can be spring-biased. There can be a removable tubular sleeve around the box and lid. The sleeve can include a tab in extension therefrom defining a hanghole for display purposes. Methods for storage and use include using arrangements of this type. The container arrangement can hold a variety of items, for example, gaming items, in particular, dice.

Abstract: A coating system (66, 68), winding system (158), finishing system (274, 276) and manufacturing system (FIGS. 6,7, 22-29) is provided for spiral-wound fluted filter media (74, 130).

Abstract: A portable, self-contained identification system comprises a base, a removable lid operatively and sealingly engageable with the base, whereby the removable lid and the base cooperate to form a sealed enclosure when the removable lid is engaged with the base. A recording device has a record microphone and a record switch and the playback device has a speaker and a playback switch. The recording switch is manually actuated to record the message and a playback switch is actuated by the depression and the release of the playback button, such that the playback switch is automatically actuated by removal of the removable lid to playback the message.

Abstract: A portable, self-contained identification system comprises a base, a removable lid operatively and sealingly engageable with the base, whereby the removable lid and the base cooperate to form a sealed enclosure when the removable lid is engaged with the base. A recording device has a record microphone and a record switch and the playback device has a speaker and a playback switch. The recording switch is manually actuated to record the message and a playback switch is actuated by the depression and the release of the playback button, such that the playback switch is automatically actuated by removal of the removable lid to playback the message.

Abstract: A vessel such as a dairy pasteuriser having a path B for product and a separate path A for coolant in intimate relationship is tested for leaks by circulating a donor fluid under pressure in path A whilst a recipient fluid such as clean tap water is circulated in path B. If the donor fluid is an electrolyte, a probe 12 is placed in path B to measure the conductivity of the recipient fluid. A rise in conductivity over a period indicates leakage between the two paths, the rate of change indicating the size of the leak. Alternatively, the donor fluid can be a gas, and leakage detected using an untrasound probe.

Abstract: A vessel such as a dairy pasteuriser having a path B for product and a separate path A for coolant in intimate relationship is tested for leaks by circulating a donor fluid under pressure in path A whilst a recipient fluid such as clean tap water is circulated in path B. The donor fluid is a gas, and leakage is detected using an ultrasound probe.

Abstract: A vessel such as a dairy pasteuriser having a path B for product and a separate path A for coolant in intimate relationship is tested for leaks by circulating a donor fluid under pressure in path A whilst a recipient fluid such as clean tap water is circulated in path B. If the donor fluid is an electrolyte, a probe (12) is placed in path B to measure the conductivity of the recipient fluid. A rise in conductivity over a period indicates leakage between the two paths, the rate of change indicating the size of the leak. Alternatively, the donor fluid can be a gas, and leakage detected using an untrasound probe.

Abstract: A pet animal toy has a body covered by a removable coat of long fur which can be cut and "groomed" to give a stylized appearance, then removed and replaced with another fur coat for cutting to give a different appearance. The coat covers substantially all the trunk of the body and the legs and appears to be fur grown on the animal. It may be secured by a concealed attachment under the body.

Abstract: An attitude sensing system which incorporates the precision in attitude sensing of a satellite navigation system with the dynamic tracking capabilities of an inertial measurement unit. Optimally estimated attitude and system error signals are combined with the outputs of an inertial measurement unit to control the phase differences of signals received on an interferometer array from a navigation satellite. The outputs from the inertial measurement unit and the phase differences are processed in an optimal estimator filter to produce periodically updated attitude and system error signals. This permits inertial attitude sensing to benefit from the long term accuracy of attitude estimation based upon signals from the satellite navigation system.