Abstract: The present invention provides compounds of Formula I, or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof for treating cellular proliferative disorders (e.g., cancer).

Abstract: Systems and methods for managing airflow across a transport system are provided. The transport system includes a main transport pipe connected to a collection area configured to collect objects and materials transported through the transport system. The systems and methods also include a branch transport pipe connected to the main transport pipe and a loading station and a loop riser pipe connecting between the main transport pipe and the branch transport pipe. The systems and methods also include a redirector configured to regulate airflow to at least one of the loop riser pipe or the main transport pipe.

Abstract: The present invention provides compounds of Formula I?, or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof for treating cellular proliferative disorders (e.g., cancer).

Abstract: An energy efficient heating, ventilation, and air conditioning (HVAC) system includes a variable capacity compressor configured to operate at a plurality to operating capacities and a control system communicatively coupled to the variable capacity compressor. The control system is configured to receive data indicative of a temperature within a conditioned space, receive data indicative of a set point temperature of the conditioned space, initialize operation of the variable capacity compressor, and ramp up operation of the variable capacity compressor to an intermediate operating capacity of the plurality of operating capacities during initial operation of the variable capacity compressor, where the intermediate operating capacity is less than a full operating capacity of the plurality of operating capacities.

Abstract: In an aspect, an HVAC system includes an inducer motor to provide combustion airflow, and a pressure sensor to measure an output airflow pressure of the inducer motor. The HVAC system may initiate the inducer motor, and receive a pulse width modulation (PWM) signal from the inducer motor, wherein the PWM signal indicates a PWM signal of the inducer motor corresponding to a predetermined airflow pressure of the inducer motor and measured by the pressure sensor. The HVAC system may compare the PWM signal to a baseline value, and control the inducer motor based on the comparing of the PWM signal to the baseline value. The HVAC system may also generate a status notification of the combustion airflow of the HVAC system in response to the comparing the PWM signal to the baseline value.

Abstract: A system faults to a return air sensor integrated within a heating, ventilation, and air conditioning (HVAC) unit. The system transmits a signal to a remote sensor. The system determines that a return signal is not received from the remote sensor. The system obtains a temperature reading from the return air sensor. The system determines whether the temperature reading satisfies a temperature setting stored in the memory. In response to determining that the temperature reading does not satisfy the temperature setting, the system enables heating or cooling of the HVAC unit until the temperature setting is satisfied. In response to determining that the temperature reading satisfies the temperature setting, the system disables heating or cooling of the HVAC unit.

Abstract: The present disclosure relates to a content distribution system enables user devices to access digital content through a variety of access elements, such as QR codes, URLs, App Clips, Data Matrix codes, and NFC tags, allowing flexible distribution of digital media without requiring a dedicated content access device. The system includes a content distribution server configured to receive check-out requests from user devices, provide metadata, and process open content commands containing identifiers of the digital content and the user. The server verifies user authorization and provides a license response to authorized devices, enabling content consumption based on licensing terms. The system can integrate with library systems to facilitate user registration and library membership applications remotely, and provides analytics for tracking user engagement and content utilization.

Abstract: The present invention provides compounds of Formula I?, or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof for treating cellular proliferative disorders (e.g., cancer).

Abstract: A heating, ventilation, and/or air conditioning (HVAC) system includes a conditioning system configured to condition a return air flow directed through the HVAC system and a control system configured to determine a difference value between an operating parameter value of the return air flow and a sensed operating parameter value of a space serviced by the HVAC system, retrieve a stored target operating parameter value of the space, and operate the HVAC system based on the difference value, the stored target operating parameter value, or both.

Abstract: A portable electronic device (PED) holder for being mounted to a structure such as a passenger seat backrest. In embodiments, the PED holder includes a socket, a hollow partial-cylinder rotatably disposed in the socket, and an adjustable clamp mounted in the hollow partial-cylinder. The hollow partial-cylinder and the socket interact via a guide mechanism configured to control rotation of the hollow partial-cylinder relative to the socket. In embodiments, the adjustable clamp is mounted to a base and includes first and second arms, at least one of which is spring-loaded. In some embodiments, an electromagnetic induction coil may be disposed in the base.

Abstract: A heating, ventilation, and/or air conditioning (HVAC) system includes secondary control circuitry configured to communicatively couple to primary control circuitry of the HVAC system that is configured to operate the HVAC system in a variable operating mode. The secondary control circuitry is configured to cause operation of the HVAC system in a calibration mode to determine a calibrated target temperature and transmit the calibrated target temperature to the primary control circuitry to enable operation of the HVAC system in the variable operating mode via the primary control circuitry based on the calibrated target temperature.

Abstract: Digital content distribution methods, systems and devices are provided. The digital content distribution utilizes a content distribution server for providing a user device access to digital content. In certain embodiments, the content distribution server: (a) receives a check-out request from a user device via a content access device; (b) provides metainfo to the user device via the content access device; (c) receives an open content command comprising an identifier of the digital content and an identifier for a user from the user device; (d) determines from the open content command whether the user device is authorized to view the digital content; and (e) provides a license response to the user device based on the user device being authorized to view the digital content, the license response comprising a license and the digital content.

Abstract: A trailer towable compact telehandler having an operator cab with an internal width greater than 700 mm and a curbside weight less than 2950 kg. Also included is a telehandler having a side-mounted engine which extends through a side wall of the chassis and under a lifting arm of the telehandler. Also included is a compact tool carrier having a reduced fore-aft dimension between an attachment plane and a principal pivot member.

Abstract: An energy efficient heating, ventilation, and air conditioning (HVAC) system includes a variable capacity compressor configured to operate at a plurality to operating capacities and a control system communicatively coupled to the variable capacity compressor. The control system is configured to receive data indicative of a temperature within a conditioned space, receive data indicative of a set point temperature of the conditioned space, initialize operation of the variable capacity compressor, and ramp up operation of the variable capacity compressor to an intermediate operating capacity of the plurality of operating capacities during initial operation of the variable capacity compressor, where the intermediate operating capacity is less than a full operating capacity of the plurality of operating capacities.

Abstract: An energy efficient heat pump includes a working fluid circuit configured to circulate a working fluid, where the working fluid circuit includes a compressor, a first heat exchanger, a second heat exchanger, a first expansion device, an economizer, and a reversing valve, where the reversing valve is configured to adjust a flow direction of the working fluid through the working fluid circuit. The energy efficient heat pump also includes a first conduit of the working fluid circuit, where the first conduit extends between the first heat exchanger and the second heat exchanger, the economizer is disposed along the first conduit, and the first conduit is configured to direct the working fluid between the first heat exchanger and the second heat exchanger and through the economizer.

Abstract: A trailer towable compact telehandler having an operator cab with an internal width greater than 700 mm and a curbside weight less than 2950 kg. Also included is a telehandler having a side-mounted engine which extends through a side wall of the chassis and under a lifting arm of the telehandler. Also included is a compact tool carrier having a reduced fore-aft dimension between an attachment plane and a principal pivot member.

Abstract: The present disclosure provides systems, apparatuses, and methods for monitoring building efficiency by a heating, ventilation, and air conditioning (HVAC) system. In an aspect, an HVAC unit including a memory and a processor coupled with the memory is disclosed. The processor may be configured to establish a current building efficiency state value of a current run cycle of the HVAC system. The processor may also be configured to determine an building efficiency state deviation value based on a difference between an average building efficiency state value of a set of previous building efficiency state values and the current building efficiency state value. The processor may further be configured to determine whether the building efficiency state deviation value satisfies a building inefficiency threshold.

Abstract: A furnace system for a heating, ventilation, and air conditioning (HVAC) system includes a furnace controller configured to determine a rolling average furnace run time of the furnace system based on a plurality of previous run cycles of the furnace system. The furnace controller is configured to segment the rolling average furnace run time into a plurality of operational time periods, wherein each operational time period is associated with a distinct fire rate of a plurality of distinct fire rates the furnace system. The furnace controller is also configured to operate the furnace system to sequentially implement the plurality of distinct fire rates associated with the plurality of operational time periods.

Abstract: In an aspect, an HVAC system includes an inducer motor to provide combustion airflow, and a pressure sensor to measure an output airflow pressure of the inducer motor. The HVAC system may initiate the inducer motor, and receive a pulse width modulation (PWM) signal from the inducer motor, wherein the PWM signal indicates a PWM signal of the inducer motor corresponding to a predetermined airflow pressure of the inducer motor and measured by the pressure sensor. The HVAC system may compare the PWM signal to a baseline value, and control the inducer motor based on the comparing of the PWM signal to the baseline value. The HVAC system may also generate a status notification of the combustion airflow of the HVAC system in response to the comparing the PWM signal to the baseline value.

Abstract: A heating, ventilation, and/or air conditioning (HVAC) system includes a conditioning system configured to condition a return air flow directed through the HVAC system and a control system configured to determine a difference value between an operating parameter value of the return air flow and a sensed operating parameter value of a space serviced by the HVAC system, retrieve a stored target operating parameter value of the space, and operate the HVAC system based on the difference value, the stored target operating parameter value, or both.