Patents by Inventor Michael BOYNE

Michael BOYNE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tolerizing Immune Modifying Nanoparticles for Overcoming the Immunogenicity of Therapeutic Vectors and Proteins
    Publication number: 20250367274
    Abstract: The present application is directed, in general, to tolerizing immune mediated particles comprising gene therapy vector antigens for use in combination with gene therapy regimens in order to reduce immunogenicity to the gene therapy vector antigens and/or transgene protein products expressed by the vectors.
    Type: Application
    Filed: April 28, 2023
    Publication date: December 4, 2025
    Inventors: John Puisis, Adam Elhofy, Joseph Podojil, Michael Boyne, Tushar Murthy
  • PREPARATION OF TOLERIZING NANOPARTICLES FOR THE TREATMENT OF PEANUT ALLERGY
    Publication number: 20250319155
    Abstract: The present disclosure relates to a process for the preparation of tolerizing immune modifying nanoparticles encapsulating peanut proteins, compositions comprising the particles and use thereof for the treatment of peanut allergy.
    Type: Application
    Filed: November 23, 2022
    Publication date: October 16, 2025
    Inventors: John Puisis, Michael Boyne, Samantha Reilly, Greta Wodarcyk, Qichen Xu, Zhiyi Lin, Timothy Toby
  • TREATMENT OF SOLID TUMORS WITH NEGATIVELY CHARGED PARTICLES
    Publication number: 20250170066
    Abstract: The present disclosure generally relates to the methods of treating solid tumors using negatively charged particles.
    Type: Application
    Filed: February 27, 2023
    Publication date: May 29, 2025
    Inventors: John Puisis, Adam Elhofy, Michael Boyne, Joseph Podojil, Tushar Murthy
  • TREATMENT OF PRIMARY BILIARY CHOLANGITIS (PBC) WITH TOLERIZING NANOPARTICLES
    Publication number: 20240408186
    Abstract: The present disclosure relates to methods of treating Primary Biliary Cholangitis (PBC) using tolerizing immune modifying nanoparticles encapsulating PBC associated antigens.
    Type: Application
    Filed: October 21, 2022
    Publication date: December 12, 2024
    Inventors: John J. Puisis, Michael Boyne, Greta Wodarcyk, Adam Elhofy
  • NEGATIVELY CHARGED PARTICLES FOR THE TREATMENT OF INFLAMMATION-RELATED BURN INJURIES
    Publication number: 20240398852
    Abstract: The present disclosure provides methods of treating burn injuries or inflammation associated with burn injuries by administering negatively charged particles.
    Type: Application
    Filed: September 29, 2022
    Publication date: December 5, 2024
    Inventor: Michael BOYNE
  • TREATMENT OF PEANUT ALLERGY WITH TOLERIZING NANOPARTICLES
    Publication number: 20240197866
    Abstract: The present disclosure relates, in general to methods of treating peanut allergy using nanoparticles encapsulating peanut antigens to induce antigen-specific tolerance.
    Type: Application
    Filed: April 15, 2022
    Publication date: June 20, 2024
    Inventors: John Puisis, James Herrmann, Michael Boyne, Adam Elhofy, Joseph Podojil, Greta Wodarcyk
  • Method of Tracking Maintenance of Immunological Tolerance
    Publication number: 20240201187
    Abstract: The present application relates, in general, to methods for tracking the induction of and long-term maintenance of antigen specific immune tolerance during administration of an antigen specific immune tolerizing therapy, such as a TIMP.
    Type: Application
    Filed: April 15, 2022
    Publication date: June 20, 2024
    Inventors: John Puisis, James Herrmann, Michael Boyne, Adam Elhofy, Joseph Podojil, Greta Wodarcyk
  • TREATMENT OF IMMUNE EVASIVE TUMORS
    Publication number: 20220257768
    Abstract: The present disclosure provides methods of treating immune evasive cancers using surface functionalized particles alone or in combination with cancer therapeutics.
    Type: Application
    Filed: July 31, 2020
    Publication date: August 18, 2022
    Inventors: John PUISIS, Adam ELHOFY, Tushar MURTHY, Michael BOYNE, Joseph PODOJIL