Patents by Inventor Michael Brands

Michael Brands has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted tricyclic compounds and methods of use thereof
    Patent number: 8524722
    Abstract: This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
    Type: Grant
    Filed: September 2, 2008
    Date of Patent: September 3, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Hartmut Schirok, Ying Li-Sommer, Michael Brands, Mario Lobell, Adrian Tersteegen, Herbert Himmel, Karl-Heinz Schlemmer, Dieter Lang, Kirstin Petersen, Matthias Renz, Dominik Mumberg, Jens Hoffmann, Gerhard Siemeister, Ulf Bömer
  • Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
    Patent number: 8338595
    Abstract: This invention relates to pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: December 25, 2012
    Assignee: Bayer HealthCare LLC
    Inventors: Julie A. Dixon, Catherine Brennan, Karl Miranda, Brent Chandler, Barton Phillips, Jianmei Fan, Michael Brands, Andrea McClure, Benjamin D. Jones, Wenlang Fu, Donald Bierer, Steven Magnuson, Harold C. E. Kluender
  • Pyrimidine Derivatives for Treatment of Hyperproliferative Disorders
    Publication number: 20110098301
    Abstract: Pyrimidine derivatives of formula pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are disclosed and claimed.
    Type: Application
    Filed: March 9, 2006
    Publication date: April 28, 2011
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Julie A. Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianqing Chen, Brian R. Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu
  • SUBSTITUTED TRICYCLIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20110021493
    Abstract: This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
    Type: Application
    Filed: September 2, 2008
    Publication date: January 27, 2011
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Hartmut Schirok, Ying Li-Sommer, Michael Brands, Mario Lobell, Adrian Tersteegen, Herbert Himmel, Karl-Heinz Schlemmer, Dieter Lang, Kirsten Petersen, Matthias Renz, Dominik Mumberg, Jens Hoffman, Gerhard Siemeister, Ulf Bömer
  • PYRIMIDINE DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE DISORDERS
    Publication number: 20100075967
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Application
    Filed: August 28, 2009
    Publication date: March 25, 2010
    Applicant: BAYER PHARMACEUTICALS CORPORATION
    Inventors: Julie A. Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianging Chen, Brian R. Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin F. Hentemann, Ann-Marie Bullion, Manoj Patel
  • PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS
    Publication number: 20100075958
    Abstract: This invention relates to pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Application
    Filed: July 20, 2009
    Publication date: March 25, 2010
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Julie A. Dixon, Catherine Brennan, Karl Miranda, Brent Chandler, Barton Phillips, Jianmei Fan, Michael Brands, Andrea McClure, Benjamin Jones, Wenlang Fu, Donald Bierer, Steven Magnuson, Harold C.E. Kluender
  • Pyrimidine derivatives for treatment of hyperproliferative disorders
    Patent number: 7678804
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: March 16, 2010
    Assignee: Bayer Healthcare LLC
    Inventors: Julie A. Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianqing Chen, Brian R. Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin F. Hentemann, Ann-Marie Bullion, Manoj Patel
  • Pyrimidine Derivatives
    Publication number: 20090286785
    Abstract: This invention relates to novel compounds (I) and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
    Type: Application
    Filed: April 7, 2006
    Publication date: November 19, 2009
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Dhanapalan Nagarathnam, Yuanwei Chen, Wenlang Fu, Donald Bierer, Ming Wang, Michael Brands, Yamin Wang, Brian R. Bear
  • Pyrimidine Derivatives
    Publication number: 20090258888
    Abstract: This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
    Type: Application
    Filed: April 7, 2006
    Publication date: October 15, 2009
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Dhanapalan Nagarathnam, Yuanwei Chen, Wenlang Fu, Donald Bierer, Ming Wang, Michael Brands, Yamin Wang, Brian R. Bear, Aaron Schmitt, Eric Mull, David Miller, Jin Zhao
  • Pyrimidine derivatives for treatment of hyperproliferative disorders
    Patent number: 7582645
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: September 1, 2009
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Julie A. Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianqing Chen, Brian Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin F. Hentemann, Ann-Marie Bullion
  • Pyrimidine derivatives for treatment of hyperproliferative disorders
    Patent number: 7582646
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: September 1, 2009
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Julie A. Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianqing Chen, Brian R. Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin F. Hentemann, Ann-Marie Bullion, Manoj Patel
  • Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
    Patent number: 7563791
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: July 21, 2009
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Julie A. Dixon, Catherine Brennan, Karl Miranda, Brent Chandler, Barton Phillips, Jianmei Fan, Michael Brands, Andrea McClure, Benjamin Jones, Wenlang Fu, Donald Bierer, Steven Magnuson, Harold C. E. Kluender
  • Pyrrolotriazine Derivatives Useful For Treating Hyper-Proliferative Disorders And Diseases Associated With Angiogenesis
    Publication number: 20070208013
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Application
    Filed: June 3, 2005
    Publication date: September 6, 2007
    Applicant: BAYER PHARMACEUTICALS CORPORATION
    Inventors: Julie Dixon, Catherine Brennan, Karl Miranda, Brent Chandler, Barton Phillips, Jianmei Fan, Michael Brands, Andrea Mcclure, Benjamin Jones, Wenlang Fu, Donald Bierer, Steven Magnuson, Harold Kluender
  • Pyrimidine derivatives for treatment of hyperproliferative disorders
    Publication number: 20070117817
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Application
    Filed: October 8, 2004
    Publication date: May 24, 2007
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Julie Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yin, Yuanwei Chen, Jianqing Chen, Brian Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin Hentemann, Ann-Marie Bullion
  • Use of substituted 2,5-diamidoindoles for the treatment of urological diseases
    Publication number: 20060183753
    Abstract: The present invention relates to the use of 2,5-diamidoindole derivatives for the preparation of medicaments for treating urological disorders in humans and/or animals.
    Type: Application
    Filed: December 6, 2003
    Publication date: August 17, 2006
    Applicant: Bayer HealthCare AG
    Inventors: Jens Erguden, Thomas Krahn, Christian Schroder, Johannes Stasch, Stefan Weigand, Hanno Wild, Michael Brands, Stehan Siegel, Dirk Heimbach, Jorg Keldenich, Masaomi Tajimi, Hiroko Takagi
  • Uracil-thioether
    Publication number: 20060122201
    Abstract: The invention relates to uracil-thioethers, pharmaceutical compositions containing said compounds and to a method for the production thereof. The invention also relates to the use of said substances in the treatment of diseases in humans and animals.
    Type: Application
    Filed: February 14, 2003
    Publication date: June 8, 2006
    Inventors: Niels Svenstrup, Alexander Kuhl, Dietmar Flubacher, Michael Brands, Kerstin Ehlert, Christoph Ladel, Michael Ottneder, Jorg Keldenich, Marcus Bauser
  • Substituted 2,5-diamidoindoles as ECE inhibitors for the treatment of cardiovascular diseases
    Patent number: 7045544
    Abstract: The invention relates to compounds of formula (I), to a method for the production thereof, and to the use of the same as pharmaceuticals for the treatment of diseases in humans and/or animals
    Type: Grant
    Filed: September 16, 2002
    Date of Patent: May 16, 2006
    Assignee: Bayer HealthCare AG
    Inventors: Jens-Kerim Ergüden, Thomas Krahn, Christian Schröder, Johannes-Peter Stasch, Stefan Weigand, Hanno Wild, Michael Brands
  • Piperidine ouracil used as a medicament for treating bacterial infections
    Publication number: 20060100224
    Abstract: The invention relates to piperidine ouracil and a method for the production thereof in addition to the use thereof in the production of medicaments for treating and/or in the prophylaxis of diseases, especially bacterial diseases.
    Type: Application
    Filed: February 13, 2003
    Publication date: May 11, 2006
    Inventors: Niels Svenstrup, Alexander Kuhl, Dietmar Flubacher, Michael Brands, Kerstin Ehlert, Christoph Ladel, Michael Otteneder, Jorg Keldenich
  • Pyrimidine derivatives for treatment of hyperproliferative disorders
    Publication number: 20050277640
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Application
    Filed: March 10, 2005
    Publication date: December 15, 2005
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Julie Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianqing Chen, Brian Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin Hentemann, Ann-Marie Bullion, Manoj Patel
  • Substituted 2 5-diamidoindoles as ece inhibitors for the treatment of cardiovascular diseases
    Publication number: 20050038101
    Abstract: The invention relates to compounds of formula (I), to a method for the production thereof, and to the use of the same as pharmaceuticals for the treatment of diseases in humans and/or animals.
    Type: Application
    Filed: September 16, 2002
    Publication date: February 17, 2005
    Inventors: Jens-Kerim Erguden, Thomas Krahn, Christian Schroder, Johannes-Peter Stasch, Stefan Weigand, Hanno Wild, Michael Brands