Abstract: The present invention pertains to novel treatments of neuropathic pain; in particular chemotherapy induced peripheral neuropathic pain (CIPNP). The invention provides antagonists cytochrome P450 epoxygenases (CYP), and more specifically antagonists of CYP2J2, as therapeutics for use in the treatment of neuropathic pain such as CIPNP. CYP2J2 antagonists were identified to alleviate CIPNP in-vivo, and therefore are provided additionally in combination with chemotherapeutics for the treatment of diseases such as cancer or other proliferative disorders. The CYP2J2 antagonists reduce chemotherapeutic induced pain and therefore allow for a higher dosing of the chemotherapeutic during cancer treatment. In addition the invention relates to the use of CYP2J2 agonists, or metabolites of CYP2J2, for sensitizing TRPV1.

Abstract: The invention relates to a bodywork of a motor vehicle comprising side members and a rear axle construction which is connected to the bodywork, the rear axle construction having means for attaching the rear axle construction to the bodywork and having a suspension, and the rear axle construction being configured as a torsion-beam axle or as a multi-link axle. The object to provide a generic bodywork of a motor vehicle with a rear axle construction which allows, in a financially favorable manner, a modular rear axle concept, i.e. the selective use of a torsion-beam axle or of a multi-link axle is achieved in that the bodywork has means for receiving the attachment means of a torsion-beam axle and of a multi-link axle and has means for receiving the attachment means and the suspension of a torsion-beam axle and of a multi-link axle.

Abstract: The invention relates to a bodywork of a motor vehicle comprising side members and a rear axle construction which is connected to the bodywork, the rear axle construction having means for attaching the rear axle construction to the bodywork and having a suspension, and the rear axle construction being configured as a torsion-beam axle or as a multi-link axle. The object to provide a generic bodywork of a motor vehicle with a rear axle construction which allows, in a financially favourable manner, a modular rear axle concept, i.e. the selective use of a torsion-beam axle or of a multi-link axle is achieved in that the bodywork has means for receiving the attachment means of a torsion-beam axle and of a multi-link axle and has means for receiving the attachment means and the suspension of a torsion-beam axle and of a multi-link axle.