Patents by Inventor Michael Brigham

Michael Brigham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LINER-FREE THROUGH-SILICON-VIAS FORMED BY SELECTIVE METAL DEPOSITION
    Publication number: 20230307321
    Abstract: Structures for a through-silicon via and methods of forming a structure for a through-silicon via. The structure includes a substrate having a trench and surfaces that border the trench. The structure further includes a through-silicon via having a layer inside the trench. The layer is in direct contact with the surfaces of the substrate.
    Type: Application
    Filed: March 28, 2022
    Publication date: September 28, 2023
    Inventors: David Thomas, Cody Soule, John G. Twombly, Michael Brigham, Bruce Porth, Vivekanand Kalaparthi
  • Hemerocallis plant named 'Striped Fantastic'
    Publication number: 20110252529
    Abstract: A new and distinct cultivar of Hemorocallis plant characterized by striking variegated leaves combined with the beautiful and large flowers of Hemorocallis ‘Kate Carpenter’.
    Type: Application
    Filed: April 12, 2010
    Publication date: October 13, 2011
    Inventors: Steven Michael Brigham, Donna Gunderson Brigham
  • Method to Assess Stability of Proteins
    Publication number: 20090298186
    Abstract: A method for determining conformational stability of proteins detects the change in free sulfhydryls accessible to reaction with a fluorescent probe after combined chemical and thermal denaturation. The method is useful in any application where the stability and integrity of a protein preparation is useful information. The method can be used to screen protein variants for desirable stability profile.
    Type: Application
    Filed: February 27, 2009
    Publication date: December 3, 2009
    Inventors: Michael Brigham-Burke, Eilyn R. Lacy
  • Surface plasmon resonance detector having collector for eluted ligate
    Patent number: 5561069
    Abstract: An improved surface plasmon resonance detector, capable of recovering a desired eluted ligate, permits the isolation and characterization of novel ligates and ligands.
    Type: Grant
    Filed: November 21, 1994
    Date of Patent: October 1, 1996
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Brigham-Burke, Daniel J. O'Shannessy
  • Surface plasmon resonance detector having collector for eluted ligate
    Patent number: 5395587
    Abstract: An improved surface plasmon resonance detector, capable of recovering a desired eluted ligate allows for the collection and subsequent analysis of ligate solutions following interaction of the ligate with an immobilized ligand on a surface of a sensor chip of the surface plasmon resonance detector, permits the isolation and characterization of novel ligates and ligands.
    Type: Grant
    Filed: July 6, 1993
    Date of Patent: March 7, 1995
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Brigham-Burke, Daniel J. O'Shannessy
  • plant named ‘Striped Fantastic’
    Patent number: PP23154
    Abstract: A new and distinct cultivar of Hemerocallis plant characterized by striking variegated leaves combined with the beautiful and large flowers of Hemerocallis ‘Kate Carpenter’.
    Type: Grant
    Filed: April 12, 2010
    Date of Patent: October 30, 2012
    Inventors: Steven Michael Brigham, Donna Gunderson Brigham