Abstract: A method for generating instruction sequences for testing a processor design model. The method includes receiving, by an instruction sequence generator (ISG), an initial test template. The initial test template includes an initial set of instruction constraints and a save resumable state command. The ISG generates a first set of executable test instructions based on the initial test template. The ISG initiates the save resumable state command. The ISG creates and saves a snapshot that includes information on a resume state of the ISG and the first set of executable test instructions at the time the save resumable state command is initiated.

Abstract: Disclosed is a selective chemical sensor, methods of production, and methods of use, where the sensor utilizes an electrochemical sensor element protected by a semi-selective polymeric matrix in conjunction with a selecting compound doped into the matrix along with an acid or base. The polymeric matrix serves as an analyte capture matrix, while the selecting compound reacts with the analyte, further improving the selectivity of the sensor.

Abstract: Systems and methods for continuous real-time sweat sampling and analysis are disclosed. A sweat collection article and method of collecting sweat from a person's skin using the sweat collection article are provided. The sweat collection article includes: a sweat collecting tube placed adjacent to the person's skin, and at least one piece of flexible material that has an adhesive that adheres the article to the person's skin and is positioned to overlie one end of the tube. The second end of the sweat collecting tube is in fluid communication with an instrument such as a mass spectrometer that analyzes the sweat on a real-time basis. The systems and methods may further include a device for removing salt from the sweat that is arranged so that the sweat is transported to the device prior to being transported to the instrument for analyzing the sweat.

Abstract: Systems and methods for continuous real-time sweat sampling and analysis are disclosed. A sweat collection article and method of collecting sweat from a person's skin using the sweat collection article are provided. The sweat collection article includes: a sweat collecting tube placed adjacent to the person's skin, and at least one piece of flexible material that has an adhesive that adheres the article to the person's skin and is positioned to overlie one end of the tube. The second end of the sweat collecting tube is in fluid communication with an instrument such as a mass spectrometer that analyzes the sweat on a real-time basis. The systems and methods may further include a device for removing salt from the sweat that is arranged so that the sweat is transported to the device prior to being transported to the instrument for analyzing the sweat.

Abstract: Systems and methods for continuous real-time sweat sampling and analysis are disclosed. In one case, a sweat collection device and method of using the same are provided. The sweat collecting device has a main body with a sweat-collecting surface that is placed adjacent the person's skin. A sweat collecting tube is provided. The first end of the sweat collecting tube is joined to a bore in the main body of the device and the second end extends outward therefrom. In another case, a sweat collection article and method of collecting sweat from a person's skin using the sweat collection article are provided. The sweat collection article includes: a sweat collecting tube placed adjacent to the person's skin, and at least one piece of flexible material that has an adhesive that adheres the article to the person's skin and is positioned to overlie one end of the tube.

Abstract: A system, apparatus, and method include a pump to deliver vapor including airborne contaminants including organic compounds including a target analyte; a collector to transfer the airborne contaminants by autonomous liquid extraction into a mobile organic liquid phase; a micro-fluidic chamber including immobilized biorecognition elements that bind to analytes delivered from the mobile organic liquid phase; a mechanism to introduce the mobile organic liquid phase to a buffer containing a plurality of substrates causing a series of biochemical reactions that create a change corresponding to a concentration of the target analyte; and a detector to perform real-time analysis that correlates to a concentration of the organic compounds to determine a presence of the target analyte.

Abstract: A method for generating instruction sequences for testing a processor design model. The method includes receiving, by an instruction sequence generator (ISG), an initial test template. The initial test template includes an initial set of instruction constraints and a save resumable state command. The ISG generates a first set of executable test instructions based on the initial test template. The ISG initiates the save resumable state command. The ISG creates and saves a snapshot that includes information on a resume state of the ISG and the first set of executable test instructions at the time the save resumable state command is initiated.

Abstract: Implementations are directed to methods, systems, and computer-readable media for data hazard generation for instruction sequence generation. In one aspect, a computer-implemented method includes: obtaining data hazard information defining a data hazard to be generated during computer instruction generation, the data hazard specifying a data dependency between a first instruction and a second instruction occurring after the first instruction, and generating, based on the data hazard information and register usage data of a plurality of registers, an instruction for execution in a current processing cycle that satisfies the data dependency specified by the data hazard. The register usage data specifies, for each register of the plurality of registers, whether data was read from or written into the register in a plurality of processing cycles preceding the current processing cycle.

Abstract: A system, apparatus, and method include a pump to deliver vapor including airborne contaminants including organic compounds including a target analyte; a collector to transfer the airborne contaminants by autonomous liquid extraction into a mobile organic liquid phase; a micro-fluidic chamber including immobilized biorecognition elements that bind to analytes delivered from the mobile organic liquid phase; a mechanism to introduce the mobile organic liquid phase to a buffer containing a plurality of substrates causing a series of biochemical reactions that create a change corresponding to a concentration of the target analyte; and a detector to perform real-time analysis that correlates to a concentration of the organic compounds to determine a presence of the target analyte.

Abstract: Systems and methods for continuous real-time sweat sampling and analysis are disclosed. In one case, a sweat collection device and method of using the same are provided. The sweat collecting device has a main body with a sweat-collecting surface that is placed adjacent the person's skin. A sweat collecting tube is provided. The first end of the sweat collecting tube is joined to a bore in the main body of the device and the second end extends outward therefrom. In another case, a sweat collection article and method of collecting sweat from a person's skin using the sweat collection article are provided. The sweat collection article includes: a sweat collecting tube placed adjacent to the person's skin, and at least one piece of flexible material that has an adhesive that adheres the article to the person's skin and is positioned to overlie one end of the tube.

Abstract: The disclosed invention provides a sensing device capable of concentrating a fluid sample with respect to a target analyte and a reference analyte, and measuring the target analyte and reference analyte in the concentrated sample. The invention includes a concentrator that may include a selectively permeable membrane, or a gel having an increasing density gradient. In another embodiment, the invention includes an air or gas gap between a fluid transport channel and the concentrator. In another embodiment, the sensing device includes a driver for electronically moving a fluid sample through the channel and membrane to cause concentration. In some embodiments, the invention may also determine the change in molarity of the fluid sample with respect to the target analyte, as the sample is concentrated by the device.

Abstract: An electrochemical sensor is provided for use in a wearable device for measuring analytes in a pH-variable biofluid. The sensor includes a plurality of aptamer sensing elements which have biorecognition elements, such as aptamers, that experience a conformational change on interaction with a target analyte in the biofluid. Each aptamer sensing element forms a first configuration before target analyte capture and a second configuration after target analyte capture. A redox moiety is paired with each aptamer sensing element. The redox moiety has a reaction potential that is at least partially independent of a pH value of the biofluid. The EAB sensor further includes an electrode operative in conjunction with the plurality of aptamer sensing elements to produce a variable signal depending upon the configuration of the aptamer sensing elements.

Abstract: The present invention provides self-assembled monolayers (SAM) configured for use with electrochemical aptamer-based biosensors, which allow sensing devices to detect very low concentrations of target analytes in a biofluid sample. Embodiments of the disclosed invention include SAMs with improved long-term stability in sweat through persistent thiolate bonds between the sensor electrode and disclosed blocker groups, or between the sensor electrode and aptamer sensing elements via disclosed binder molecules. Embodiments of the invention also include blocker groups configured to form densely packed and persistent SAMs on sensor electrodes.

Abstract: The disclosed invention provides a fluid sensing device and method capable of collecting a fluid sample, concentrating the sample with respect to one or more target analytes, and measuring the target analyte(s) in the concentrated sample. The invention is also capable of determining the change in molarity of the fluid sample with respect to the target analyte(s), as the sample is concentrated by the device. The invention further includes a method for using a fluid sensing device to concentrate a fluid sample with respect to one or more target analytes. The disclosed method further includes the ability to correlate the measured target analyte concentration to a physiological condition of a device wearer, or of a fluid source.

Abstract: The disclosed invention provides a fluid sensing device and method capable of collecting a fluid sample, concentrating the sample with respect to one or more target analytes, and measuring the target analyte(s) in the concentrated sample. The invention is also capable of determining the change in molarity of the fluid sample with respect to the target analyte(s), as the sample is concentrated by the device. The invention further includes a method for using a fluid sensing device to concentrate a fluid sample with respect to one or more target analytes. The disclosed method further includes the ability to correlate the measured target analyte concentration to a physiological condition of a device wearer, or of a fluid source.

Abstract: The disclosed invention provides a fluid sensing device and method capable of collecting a fluid sample, concentrating the sample with respect to one or more target analytes, and measuring the target analyte(s) in the concentrated sample. The invention is also capable of determining the change in molarity of the fluid sample with respect to the target analyte(s), as the sample is concentrated by the device. The invention further includes a method for using a fluid sensing device to concentrate a fluid sample with respect to one or more target analytes. The disclosed method further includes the ability to correlate the measured target analyte concentration to a physiological condition of a device wearer, or of a fluid source.

Abstract: Systems and methods for supporting E911 for VoIP mobile communications are provided. A mobile station formats a call setup message by including particular information in a header portion of the call setup message that is used by the wireless network to select an appropriate PSAP and route the call to the appropriate PSAP.

Abstract: Systems and methods for supporting E911 for VoIP mobile communications are provided. A mobile station formats a call setup message by including particular information in a header portion of the call setup message that is used by the wireless network to select an appropriate PSAP and route the call to the appropriate PSAP.