Patents by Inventor Michael Brucato

Michael Brucato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Degradation-resistant glucocorticosteroid formulations
    Publication number: 20030113268
    Abstract: The present invention thus provides chemically and physically stable formulations of glucocorticosteroids obtained by formulating the glucocorticosteroid with a cosolvent, a propellant and a radical quencher where the glucocorticosteroid remains chemically and physically stable under standard conditions.
    Type: Application
    Filed: January 24, 2002
    Publication date: June 19, 2003
    Inventors: Mina Buenafae, Michael Brucato, Kai Zhang
  • Pressurized metered dose inhalers and pharmaceutical aerosol fomulations
    Publication number: 20030077230
    Abstract: Provided are pressurized metered dose inhalers containing stable formulations of a &bgr;-agonist drug in suspension or solution. Also provided are aerosol formulations suitable for inhalation therapy containing a &bgr;-agonist drug in suspension or solution.
    Type: Application
    Filed: July 2, 2002
    Publication date: April 24, 2003
    Inventors: Frank E. Blondino, Michael Brucato, Maria W. Buenafe
  • Degradation-resistant glucocorticosteroid formulations
    Publication number: 20030053957
    Abstract: The present invention thus provides chemically and physically stable formulations of glucocorticosteroids (such as, for example, budesonide) obtained by formulating the glucocorticosteroid with a cosolvent (such as ethanol), a propellant (such as HFA-134a, HFA-227ea, or both), and a radical quencher such as ascorbyl palmitate) where the glucocorticosteroid remains chemically and physically stable under standard conditions.
    Type: Application
    Filed: June 20, 2002
    Publication date: March 20, 2003
    Inventors: Mina Buenafae, Michael Brucato, Kai Zhang
  • Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
    Patent number: 6451285
    Abstract: Provided are pressurized metered dose inhalers containing stable formulations of a &bgr;-agonist drug in suspension or solution. Also provided are aerosol formulations suitable for inhalation therapy containing a &bgr;-agonist drug in suspension or solution.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: September 17, 2002
    Assignee: Baker Norton Pharmaceuticals, Inc.
    Inventors: Frank E. Blondino, Michael Brucato, Maria W. Buenafe
  • Pharmaceutical aerosol formulations containing fluoroalkanes and budesonide
    Publication number: 20020127185
    Abstract: Provided is a solution aerosol formulation adapted for use in a pressurized aerosol container. The aerosol formulation is formulated from a composition containing Budesonide, at least one fluoroalkane propellant, and a cosolvent present in an amount that dissolves or solubilizes the Budesonide in the mixture of cosolvent and propellant.
    Type: Application
    Filed: July 24, 2001
    Publication date: September 12, 2002
    Inventors: Frank E. Blondino, Michael Brucato, Maria W. Buenafe, Kelly A. Cavanaugh, Raul A. Medina
  • Degradation-resistant glucocorticosteroid formulations
    Publication number: 20020085978
    Abstract: The present invention thus provides chemically and physically stable formulations of glucocorticosteroids (such as, for example, budesonide) obtained by formulating the glucocorticosteroid with a cosolvent (such as ethanol), a propellant (such as HFA-134a, HFA-227ea, or both), and a radical quencher (such as ascorbyl palmitate), where the glucocorticosteroid remains chemically and physically stable under standard conditions
    Type: Application
    Filed: January 24, 2001
    Publication date: July 4, 2002
    Inventors: Mina Buenafe, Michael Brucato, Kai Zhang
  • PRESSURIZED METERED DOSE INHALERS AND PHARMACEUTICAL AEROSOL FORMULATIONS
    Publication number: 20020018753
    Abstract: Provided are pressurized metered dose inhalers containing stable formulations of a &bgr;-agonist drug in suspension or solution. Also provided are aerosol formulations suitable for inhalation therapy containing a &bgr;-agonist drug in suspension or solution.
    Type: Application
    Filed: June 19, 1998
    Publication date: February 14, 2002
    Inventors: FRANK E. BLONDINO, MICHAEL BRUCATO, MARIA BUENAFE
  • Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide
    Patent number: 6290930
    Abstract: Provided is a solution aerosol formulation adapted for use in a pressurized aerosol container. The aerosol formulation is formulated from a composition containing Budesonide, at least one fluoroalkane propellant, and a cosolvent present in an amount that dissolves or solubilizes the Budesonide in the mixture of cosolvent and propellant.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: September 18, 2001
    Assignee: Baker Norton Pharmaceuticals, Inc.
    Inventors: Frank E. Blondino, Michael Brucato, Maria Buenafe, Kelly A. Cavanaugh, Raul A. Medina
  • Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol
    Patent number: 6004537
    Abstract: Provided is a solution aerosol formulation adapted for use in a pressurized aerosol container. The aerosol formulation is formulated from a composition containing Budesonide, Formoterol at least one fluoroalkane propellant, and a cosolvent present in an amount that dissolves or solubilizes the Budesonide and Formoterol in the mixture of cosolvent and propellant.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: December 21, 1999
    Assignee: Baker Norton Pharmaceuticals, Inc.
    Inventors: Frank E. Blondino, Michael Brucato, Maria W. Buenafe, Kelly A. Cavanaugh