Abstract: Provided are implantable biomedical devices and related methods for interfacing with a target tissue. The devices comprise a substrate, an electronic device supported by the substrate and a freely positionable injectable needle electronically connected to the electronic device by a deformable interconnect, where the injectable needle has one or more optical sources provided on a distal tip end. The injectable needle may further comprise a photodetector.

Abstract: Provided are implantable biomedical devices and related methods for interfacing with a target tissue. The devices comprise a substrate, an electronic device supported by the substrate and a freely positionable injectable needle electronically connected to the electronic device by a deformable interconnect, where the injectable needle has one or more optical sources provided on a distal tip end. The injectable needle may further comprise a photodetector.

Abstract: Provided are fully implantable soft medical devices and related methods. The devices comprise stretchable electronic devices between on an elastomeric substrate and an elastomeric super-state. Electronic components of the electronic device are configured to interface with tissue. Wireless power and control systems provide wireless power and control of the electronic components, thereby providing the fully implantable functionality. The devices may have a plurality of independently addressable electronic components, such as LEDs. In this manner, wireless control of a single implanted device may still provide multi-functional capabilities, including in a multiplexed configuration.