Patents by Inventor Michael Bukin

Michael Bukin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220370198
    Abstract: An assembly and associated method for a commissure of a prosthetic heart valve is disclosed. As one example, a method includes forming a plurality of commissures with a plurality of leaflets of a prosthetic heart valve, wherein each commissure is formed by: folding each commissure tab of each leaflet into a series of overlapping layers, each folded commissure tab arranged outward of, in a lateral direction, a portion of a body of the leaflet that is directly connected to the commissure tab; pairing each folded commissure tab of each leaflet with a folded commissure tab of another leaflet; and securing at least a portion of the series of overlapping layers of each folded commissure tab in its folded configuration.
    Type: Application
    Filed: August 4, 2022
    Publication date: November 24, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Noam Nir, Elena Sherman, Michael Bukin, Tamir S. Levi, Ziv Yohanan, David Maimon
  • Publication number: 20220346949
    Abstract: A prosthetic valve assembly includes a radially expandable and compressible annular frame. The frame includes a plurality of interconnected struts, which include a plurality of inner struts and a plurality of outer struts. The inner struts overlap adjacent outer struts at a plurality of pivot joints. Radial expansion or compression of the annular frame causes the inner struts to pivot relative to the outer struts at the pivot joints. The assembly also includes a valvular structure having a plurality of leaflets, each leaflet having a cusp edge portion. The assembly further includes one or more leaflet-supporting cords, each having a plurality of anchoring portions and a plurality of suspended portions, each suspended portion extending between two adjacent anchoring portions. The anchoring portions are affixed to respective anchoring features of the frame adjacent the pivot joints. The cusp edge portions of the leaflets are connected to the suspended portions.
    Type: Application
    Filed: July 12, 2022
    Publication date: November 3, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Dikla Kersh, Michael Bukin, Tamir S. Levi, Noam Nir
  • Publication number: 20220331096
    Abstract: A method of implanting a prosthetic heart valve within a patient can comprise inserting a distal end portion of a delivery apparatus and a prosthetic heart valve into the patient and advancing the prosthetic heart valve to a deployment location within the heart of the patient and inflating one or more of a plurality of differently-sized balloons in a balloon-assembly on the distal end portion of the delivery apparatus. The prosthetic heart valve can be mounted on the balloon assembly in a crimped state and the inflating of the one or more of the plurality of differently-sized balloons can expand the prosthetic heart valve from the crimped state to a radially expanded state having a non-cylindrical shape.
    Type: Application
    Filed: April 22, 2022
    Publication date: October 20, 2022
    Inventors: Ziv Yohanan, Tamir S. Levi, Netanel Benichou, Michael Bukin, Nikolay Gurovich, Elena Sherman
  • Publication number: 20220323209
    Abstract: An assembly and associated method for a commissure of a prosthetic heart valve is disclosed. As one example, a method includes forming each of a plurality of commissures with a plurality of leaflets by pairing a first commissure tab of a first leaflet with an adjacent, second commissure tab of a second leaflet, folding a support strip over an inner reinforcing element, positioning the folded support strip between the first and second commissure tabs, and attaching first and second outer reinforcing elements to the first and second commissure tabs, respectively, via stitching, the stitching extending over at least a portion of the first reinforcing element opposite a fold region of the support strip, and, for each commissure, securing end portions of the support strip to a respective support portion of a frame of the prosthetic heart valve.
    Type: Application
    Filed: June 28, 2022
    Publication date: October 13, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Noam Nir, Michael Bukin, Elena Sherman
  • Publication number: 20220323210
    Abstract: Assembly methods for installing a leaflet assembly to an expandable frame of a prosthetic heart valve are described. The leaflet assembly comprises a plurality of leaflets coupled together at adjacent tabs, which form respective commissure tab assemblies. The commissure tab assemblies are inserted into corresponding windows of support members of the expandable frame. One or more wedge members are inserted into the commissure tab assembly, e.g., between the adjacent tabs or with the adjacent tabs therebetween, to restrain radial motion of the commissure tab assembly with respect to the window. The window can be a closed window, and the wedge member insertion can be after the commissure tab assembly is inserted into the window. Alternatively, the window can be an open window or channel, and the wedge member insertion can be before the commissure tab assembly is installed in the window.
    Type: Application
    Filed: June 28, 2022
    Publication date: October 13, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Noam Nir, Elena Sherman, Tamir S. Levi, Michael Bukin
  • Publication number: 20220287834
    Abstract: A belt for an implantable prosthetic device can include an annular body including a plurality of alternating peaks and valleys and a plurality of frangible members extending between at least one of adjacent peaks and adjacent valleys. The annular body can be radially expandable from a radially compressed configuration to a first diameter upon application of a radially outwardly directed force via an expandable implantable prosthetic device. A first frangible member of the plurality of frangible members can be configured to break when the radially outwardly directed force exceeds a first predetermined threshold to allow radial expansion of the annular body to a second diameter.
    Type: Application
    Filed: May 27, 2022
    Publication date: September 15, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Tal Reich, Noam Nir, Ziv Yohanan, Tamir S. Levi, Michael Bukin
  • Publication number: 20220265445
    Abstract: An implantable prosthetic valve comprises an annular frame that is radially expandable from a radially compressed state to a radially expanded state. The frame has an inflow end, an outflow end, and a longitudinal axis extending from the inflow end to the outflow end. The prosthetic valve also comprises a plurality of leaflets positioned to regulate a flow of blood from the inflow end to the outflow end of the frame, and a skirt assembly. The skirt assembly comprises a laminate having a textile layer sandwiched between a first encapsulation layer and a second encapsulation layer. The first and second encapsulation layers are made of an elastomer and the textile layer comprises a first set of yarns and a second set of yarns interwoven with the first set of yarns, wherein the first and second sets of yarns are non-perpendicular and non-parallel to the longitudinal axis.
    Type: Application
    Filed: May 5, 2022
    Publication date: August 25, 2022
    Inventors: Michael Bukin, Tamir S. Levi
  • Publication number: 20220257367
    Abstract: An implantable prosthetic valve can include a frame movable between a radially compressed and a radially expanded configuration. The frame can include a first strut having a first locking feature disposed on a radially facing inner surface of the strut and a second strut having a second locking feature disposed on a radially facing outer surface of the strut. The first and second locking features can engage each other so as to allow pivoting of the first and second struts relative to one another in a first direction upon radial expansion of the frame and resist pivoting of the first and second struts relative to one another in a second direction to resist radial compression of the frame.
    Type: Application
    Filed: April 29, 2022
    Publication date: August 18, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Yair A. Neumann, Oren Cohen, Khen Perlmutter, Eitan Atias, Noam Miller, Eran Goldberg, Anatoly Dvorsky, Tamir S. Levi, Haim Yushtein, Danny M. Garmahi, Ziv Yohanan, Michael Bukin, Noam Nir, Elena Sherman, Gideon Sagi
  • Publication number: 20220249227
    Abstract: A leaflet assembly for a prosthetic heart valve is disclosed. As one example, a method includes: forming a plurality of leaflet sub-assemblies, each including a leaflet and a skirt and formed by placing the skirt on one side of the leaflet such that the skirt extends along a curved cusp edge portion and two commissure tabs of the leaflet, folding two end portions of the skirt around corresponding commissures tabs, stitching each folded end portion to a corresponding commissure tab to form a respective half commissure portion, and stitching the skirt to the cusp edge portion and forming the leaflet assembly by pairing each half commissure portion of each leaflet sub-assembly with a half commissure portion of another leaflet sub-assembly to form a plurality of pairs of adjacent half commissure portions, and for each pair, stitching the adjacent half commissure portions to each other to form a commissure.
    Type: Application
    Filed: April 27, 2022
    Publication date: August 11, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Noam Nir, Michael Bukin, Elena Sherman
  • Publication number: 20220241070
    Abstract: A system can include a delivery catheter comprising a balloon and an implantable prosthetic heart valve. The prosthetic valve can have a plastically expandable and compressible unitary frame comprising a plurality of circumferentially extending rows of angled struts, including first, second, and third rows of angled struts forming rows of diamond-shaped cells, and a valvular structure comprising a plurality of leaflets. A cusp edge portion of each leaflet is connected to the frame by a skirt that is disposed between the frame and the cusp edge portions, the skirt being sutured to selected struts of the frame along diagonal paths extending from an inflow end portion toward an outflow end portion. Each diagonal path along which the skirt is sutured to the frame extends along the first, second, and third rows of angled struts.
    Type: Application
    Filed: April 13, 2022
    Publication date: August 4, 2022
    Inventors: Nikolay Gurovich, Michael Bukin, Elena Sherman, Tamir S. Levi, Ziv Yohanan, Gil Senesh, Dikla Kersh, Alexey Tsypenyuk, Waina Michelle Chu, Alexander Barash
  • Publication number: 20220241071
    Abstract: A system can include a delivery catheter comprising a balloon and an implantable prosthetic heart valve. The prosthetic valve can have a plastically expandable and compressible unitary frame comprising first, second, and third rows of angled struts that define two circumferentially extending rows of diamond-shaped cells that extend continuously around the frame, and a valvular structure comprising a plurality of leaflets. A cusp edge portion of each leaflet is connected to the frame by a skirt that is connected to and disposed between the frame and the cusp edge portions of the leaflets, the skirt being connected to consecutive struts in the first, second, and third rows of struts with sutures. The compressed prosthetic heart valve can be mounted around the balloon and radially expanded to the expanded configuration with the balloon inside a patient's body.
    Type: Application
    Filed: April 18, 2022
    Publication date: August 4, 2022
    Inventors: Nikolay Gurovich, Michael Bukin, Elena Sherman, Tamir S. Levi, Ziv Yohanan, Gil Senesh, Dikla Kersh, Alexey Tsypenyuk, Waina Michelle Chu, Alexander Barash
  • Patent number: 11399932
    Abstract: A prosthetic valve assembly includes a radially expandable and compressible annular frame. The frame includes a plurality of interconnected struts, which include a plurality of inner struts and a plurality of outer struts. The inner struts overlap adjacent outer struts at a plurality of pivot joints. Radial expansion or compression of the annular frame causes the inner struts to pivot relative to the outer struts at the pivot joints. The assembly also includes a valvular structure having a plurality of leaflets, each leaflet having a cusp edge portion. The assembly further includes one or more leaflet-supporting cords, each having a plurality of anchoring portions and a plurality of suspended portions, each suspended portion extending between two adjacent anchoring portions. The anchoring portions are affixed to respective anchoring features of the frame adjacent the pivot joints. The cusp edge portions of the leaflets are connected to the suspended portions.
    Type: Grant
    Filed: July 29, 2020
    Date of Patent: August 2, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Dikla Kersh, Michael Bukin, Tamir S. Levi, Noam Nir
  • Publication number: 20220233305
    Abstract: A method of implanting a prosthetic heart valve within a patient can comprise inserting a distal end portion of a delivery apparatus and a prosthetic heart valve into the patient and advancing the prosthetic heart valve to a deployment location within the heart of the patient and inflating one or more of a plurality of differently-sized balloons in a balloon-assembly on the distal end portion of the delivery apparatus. The prosthetic heart valve can be mounted on the balloon assembly in a crimped state and the inflating of the one or more of the plurality of differently-sized balloons can expand the prosthetic heart valve from the crimped state to a radially expanded state having a non-cylindrical shape.
    Type: Application
    Filed: April 8, 2022
    Publication date: July 28, 2022
    Inventors: Ziv Yohanan, Tamir S. Levi, Netanel Benichou, Michael Bukin, Nikolay Gurovich, Elena Sherman
  • Publication number: 20220202568
    Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame including a plurality of angled strut members, a plurality of leaflets disposed within the frame and secured to the frame, and a skirt member secured to the frame. The skirt member is disposed about an edge portion of a leaflet of the plurality of leaflets, and the skirt member includes a plurality of extension portions wrapped around at least one strut member. A cord member is threaded through at least a portion of the plurality of extension portions in a direction along an axis of the at least one strut member to secure the skirt member to the at least one strut member.
    Type: Application
    Filed: March 14, 2022
    Publication date: June 30, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Tomer Saar, Michael Bukin, Elena Sherman, Alexander Barash, Yana Mayatskaya
  • Publication number: 20220192831
    Abstract: Devices, systems and methods for situating a device within a variety vasculature morphologies are provided. An expandable device can adapt to the local vasculature morphology and still provide a controlled inner diameter is described. A device for situating within the inferior vena cava and superior vena cava is described. Systems and methods for utilizing devices are described.
    Type: Application
    Filed: March 11, 2022
    Publication date: June 23, 2022
    Inventors: Nikolay Gurovich, Michael Bukin, Boaz Manash, Eason Michael Abbott, John J. Desrosiers, Christine Marie Heyninck-Jantz
  • Publication number: 20220160505
    Abstract: Disclosed are techniques for construction of prosthetic heart valves, particularly techniques for attachment of scalloped edges of valvular leaflets to struts of mechanical frames using sutures and/or other materials as intermediate coupling members. In some embodiments, the scalloped edges of the leaflets are coupled to the segments of the struts of the frame via suture loops that are oriented transverse to the scalloped edges of the leaflets. In some embodiments, central portions of scallop line segments are attached to the scalloped edges of the leaflets and are not attached to the frame. In some embodiments, strut segments are tapered to limit translation of suture loops. In some embodiments, a cloth strip couples the scalloped edges of the leaflets to frame struts. In some embodiments, the scalloped edge is attached to adjacent segments of intersecting struts via sliding suture loops, where the adjacent segments join at a common pivot joint.
    Type: Application
    Filed: February 10, 2022
    Publication date: May 26, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Noam Nir, Michael Bukin, Ziv Yohanan, Tamir S. Levi, Elena Sherman
  • Publication number: 20220160507
    Abstract: A prosthetic heart valve and delivery device for delivering the prosthetic heart valve to a target implantation site, which reduce contact between the prosthetic heart valve and a delivery sheath through which the delivery device is advanced to the target implantation site, is disclosed. As one example, a prosthetic heart valve may comprise a frame including a first end with a plurality of apices spaced apart from one another around a circumference of the first end and a cover element covering the plurality of apices. The cover element may include a cushioning element or a bio-resorbable element.
    Type: Application
    Filed: February 11, 2022
    Publication date: May 26, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Nikolay Gurovich, Michael Bukin, Elena Sherman, Alexey Tsypenyuk
  • Publication number: 20220110742
    Abstract: Various mechanically expandable prosthetic heart valves, as well as deliver apparatus, delivery assemblies, and methods for implanting such prosthetic heart valves. In one example, a prosthetic heart valve includes a mechanically expandable frame, a valve structure, and an actuator. The frame includes a plurality of struts and is movable between a radially compressed state and a radially expanded state. The valve structure includes a plurality of leaflets. The actuator is coupled to the frame and comprises an actuation lumen, a locking member, and a locking element. The actuation lumen is circumferentially spaced and axially parallel to the locking member. The actuation lumen is configured for receiving an axially movable actuation shaft that can move the frame between the radially compressed state and the radially expanded state. The locking element is rotatably coupled to the locking member and is configured to lock the frame at a desired state.
    Type: Application
    Filed: December 20, 2021
    Publication date: April 14, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Tamir S. Levi, Michael Bukin, Noam Nir, Ziv Yohanan, Elazar Levi Schwarcz, Oren Cohen, Ofir Witzman, Eitan Atias, Noam Miller, Khen Perlmutter, Boaz Manash, Eyal Leiba, Eran Goldberg
  • Patent number: 11273031
    Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame including a plurality of angled strut members, and a skirt member secured to the frame. The skirt member includes a plurality of extension portions wrapped around at least one strut member adjacent the extension portions. The prosthetic valve further includes a cord member threaded through at least a portion of the plurality of extension portions to secure the skirt member to the at least one strut member.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: March 15, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Tomer Saar, Michael Bukin, Elena Sherman, Alexander Barash, Yana Mayatskaya
  • Publication number: 20220023038
    Abstract: A prosthetic valve has an annular frame including a plurality of strut members that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. A leaflet structure is situated at least partially within the frame. The leaflet structure includes a plurality of leaflets, each leaflet having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form a commissure. The commissure tab portions of each leaflet are folded to form a plurality of layers positioned on the inside of the frame. A reinforcement member is positioned between the layers of each commissure tab portion.
    Type: Application
    Filed: October 1, 2021
    Publication date: January 27, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Nikolay Gurovich, Michael Bukin, Alexey Tsypenyuk, Elena Sherman, Dikla Kersh, Boaz Manash, Liron Tayeb, Ziv Yohanan, Alexander Barash, Yair A. Neumann, Tomer Saar