Abstract: A cardiac assembly (1520, 1620, 1920) includes a cardiac treatment device (1532, 2132), which is configured to replace or improve function of a native atrioventricular valve, and a ventricular anchor (1530), which is configured to be positioned in a ventricle of the heart so as to support the cardiac treatment device (1532, 2132). The ventricular anchor (1530) includes (a) a proximal subannular anchor (1554), which is configured to be positioned at least partially in a target subannular space; (b) a distal anchor (1558), which is configured to be positioned partially against the ventricular wall outside the target subannular space, so as to push on the proximal subannular anchor (1554) to help anchor it in place within the target subannular space; and (c) a springy linking section (1537), which connects the proximal subannular anchor (1554) to the distal anchor (1558) such that they can articulate with respect to each other with at least one degree of freedom. Other embodiments are also described.

Abstract: A coaptation-assist device is provided for treating a native atrioventricular valve. The coaptation-assist device includes a ventricular anchor and a neo-leaflet. The ventricular anchor includes a subannular anchor and a ventricular wall anchor. The subannular anchor is configured to be anchored in position in a subannular space of a target native leaflet of the native atrioventricular valve. The ventricular wall anchor includes one or more anchor-loop wire loops, which are configured to be anchored in position against a ventricular wall outside the subannular space. The neo-leaflet is supported by the ventricular anchor and is configured to at least partially replace function of the target native leaflet by providing a surface of coaptation for one or more opposing native leaflets that oppose the target native leaflet, when the ventricular anchor is positioned in the ventricle. Other embodiments are also described.

Abstract: Coaptation-assist devices (20) are provided for treating a native atrioventricular valve. The coaptation-assist devices (20) include a ventricular anchor (30), which includes one or more wires (35), and which is configured to be positioned in a ventricle; and a neo-leaflet (32), which is supported by the ventricular anchor (30) and is configured to at least partially replace function of a target native leaflet of the native atrioventricular valve by providing a surface of coaptation (34) for one or more opposing native leaflets. In some configurations, the ventricular anchor (30) includes a proximal subannular anchor (54), which includes a digitate anchor (56) that is shaped so as to define a plurality of fingers (60) having a plurality of curved superior peaks (66) that point in a superior direction and engage a subannular surface of the target native leaflet. Other embodiments are also described.

Abstract: Coaptation-assist devices (20) are provided for treating a native atrioventricular valve. The coaptation-assist devices (20) include a ventricular anchor (30), which includes one or more wires (35), and which is configured to be positioned in a ventricle; and a neo-leaflet (32), which is supported by the ventricular anchor (30) and is configured to at least partially replace function of a target native leaflet of the native atrioventricular valve by providing a surface of coaptation (34) for one or more opposing native leaflets. In some configurations, the ventricular anchor (30) includes a proximal subannular anchor (54), which includes a digitate anchor (56) that is shaped so as to define a plurality of fingers (60) having a plurality of curved superior peaks (66) that point in a superior direction and engage a subannular surface of the target native leaflet. Other embodiments are also described.

Abstract: A coaptation-assist device (20, 120A, 120B, 120C, 320A, 320B, 420, 720) is provided for treating a native atrioventricular valve, including a loop-shaped ventricular anchor (30, 130, 330, 430, 730) which includes an anchor-loop wire loop (50, 150, 350, 450, 750), which defines at least a portion of a border of the loop-shaped ventricular anchor, and is configured to be positioned in a ventricle, extending between a ventricular apical area and a subannular surface of a target native leaflet, and to remain anchored in position against surrounding anatomy, including the subannular surface, a ventricular wall, and the ventricular apical area. A neo-leaflet (32, 132A, 132B, 132C, 332A, 332B, 332A, 332B, 432, 732) is supported by the loop-shaped ventricular anchor and is configured to at least partially replace function of the target native leaflet by providing a surface of coaptation (34, 434, 734) for one or more opposing native leaflets that oppose the target native leaflet. Other embodiments are also described.