Patents by Inventor Michael C. Carroll

Michael C. Carroll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR DETECTING AND TREATING SCHIZOPHRENIA
    Publication number: 20190033329
    Abstract: The invention provides methods of treating schizophrenia in a subject, including for example, administering to the subject an agent that inhibits expression or activity of a C4A polynucleotide or polypeptide. The invention also provides methods of identifying a subject having or at risk of developing schizophrenia involving measuring or detecting an alteration in the level, copy number, and/or sequence of complement component C4A or complement component C4B relative to a reference.
    Type: Application
    Filed: January 24, 2017
    Publication date: January 31, 2019
    Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: STEVEN A. MCCARROLL, ASWIN SEKAR, MICHAEL C. CARROLL, BETH STEVENS
  • Natural IGM antibodies and inhibitors thereof
    Patent number: 9914751
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: March 13, 2018
    Assignees: Children's Medical Center Corporation, President and Fellows of Harvard College, The Brigham and Women's Hospital, Inc.
    Inventors: Michael C. Carroll, Francis D. Moore, Jr., Herbert B. Hechtman
  • Natural IGM Antibodies and Inhibitors Thereof
    Publication number: 20170342109
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Application
    Filed: May 8, 2017
    Publication date: November 30, 2017
    Inventors: Michael C. Carroll, Francis D. Moore, JR., Herbert B. Hechtman
  • Natural IgM antibodies and inhibitors thereof
    Patent number: 9657060
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Grant
    Filed: April 9, 2013
    Date of Patent: May 23, 2017
    Assignees: Children's Medical Center Corporation, President and Fellows of Harvard College, The Brigham and Women's Hospital, Inc.
    Inventors: Michael C. Carroll, Francis D. Moore, Herbert B. Hechtman
  • NATURAL IGM ANTIBODIES AND INHIBITORS THEREOF
    Publication number: 20160280740
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Application
    Filed: July 23, 2015
    Publication date: September 29, 2016
    Inventors: Michael C. Carroll, Francis D. Moore, JR., Herbert B. Hechtman
  • Natural IgM Antibodies
    Publication number: 20100136684
    Abstract: The invention provides natural IgM antibodies that may be used to induce inflammatory diseases or disorders such as ischemia-reperfusion injury to create animal models of such inflammatory diseases or disorders.
    Type: Application
    Filed: August 28, 2009
    Publication date: June 3, 2010
    Inventors: Michael C. Carroll, Francis D. Moore, JR., Herbert B. Hechtman
  • Natural IGM Antibodies and Inhibitors Thereof
    Publication number: 20090176966
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Application
    Filed: October 28, 2008
    Publication date: July 9, 2009
    Inventors: Michael C. Carroll, Francis D. Moore, JR., Herbert B. Hechtman
  • Natural IgM antibodies and inhibitors thereof
    Patent number: 7442783
    Abstract: The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
    Type: Grant
    Filed: March 1, 2005
    Date of Patent: October 28, 2008
    Assignees: The CBR Institute for Biomedical Research, Inc., President and Fellows of Harvard College, The Brigham and Women's Hospital, Inc.
    Inventors: Michael C. Carroll, Francis D. Moore, Jr., Herbert B. Hechtman
  • Methods and compositions for inhibiting immunoglobulin-mediated reperfusion injury
    Publication number: 20040131607
    Abstract: Methods and compositions for treating or preventing immunoglobulin-mediated reperfusion or ischemic injury, in a subject, are provided. Methods for identifying inhibitors of an interaction between a pathogenic immunoglobulin and ischemic antigen or a component of the complement pathway are provided.
    Type: Application
    Filed: October 6, 2003
    Publication date: July 8, 2004
    Inventors: Michael C. Carroll, Francis D Moore Jr, Herbert B. Hechtman