Abstract: A display system and method for an aircraft simultaneously displays the terrain under the flight plan, or under the current track of the aircraft, as both a two-dimensional lateral situation view image and as a perspective vertical situation view image. This provides improved tactical flight planning, and that does not erroneously show the flight plan passing through the displayed terrain.

Abstract: Methods and systems for displaying a digital terrain to a user of a vehicle are provided. First, second, and third actual terrain data points are received. The third actual terrain data point is between the first and second actual terrain data points. If the third actual terrain data point is above a line interconnecting the first and second actual terrain data points, the first actual terrain data point is modified such that the third actual terrain data point is not above a line interconnecting said modified first actual terrain data point and the second actual terrain data point. A digital terrain is displayed to the user of the vehicle. The digital terrain includes a first digital terrain data point corresponding to the modified first actual terrain data point.

Abstract: A display system for an aircraft includes a processing unit configured to determine a touchdown point for the aircraft and to supply display commands associated with the touchdown point; and a display device coupled the processing unit and configured to receive the display commands and operable to render symbology representing the touchdown point.

Abstract: A display system for an aircraft includes a processing unit configured to determine a touchdown point for the aircraft and to supply display commands associated with the touchdown point; and a display device coupled the processing unit and configured to receive the display commands and operable to render symbology representing the touchdown point.

Abstract: Methods and systems for displaying a digital terrain to a user of a vehicle are provided. First, second, and third actual terrain data points are received. The third actual terrain data point is between the first and second actual terrain data points. If the third actual terrain data point is above a line interconnecting the first and second actual terrain data points, the first actual terrain data point is modified such that the third actual terrain data point is not above a line interconnecting said modified first actual terrain data point and the second actual terrain data point. A digital terrain is displayed to the user of the vehicle. The digital terrain includes a first digital terrain data point corresponding to the modified first actual terrain data point.

Abstract: A display system and method for an aircraft simultaneously displays the terrain under the flight plan, or under the current track of the aircraft, as both a two-dimensional lateral situation view image and as a perspective vertical situation view image. This provides improved tactical flight planning, and that does not erroneously show the flight plan passing through the displayed terrain.

Abstract: A display system and method for an aircraft simultaneously displays the terrain under the flight plan, or under the current track of the aircraft, as both a two-dimensional lateral situation view image and as a perspective vertical situation view image. This provides improved tactical flight planning, and that does not erroneously show the flight plan passing through the displayed terrain.

Abstract: A display system and method for an aircraft simultaneously displays the terrain under the flight plan, or under the current track of the aircraft, as both a two-dimensional lateral situation view image and as a perspective vertical situation view image. This provides improved tactical flight planning, and that does not erroneously show the flight plan passing through the displayed terrain.

Abstract: An avionics system includes a display device that is viewable by a user of an aircraft and a processor in operable communication with the display device. The processor is configured to display a digital terrain having a digital landmark thereon on the display device, the digital terrain being representative of an actual terrain and the digital landmark being representative of an actual landmark on the actual terrain, and display a plurality of position indicators over the digital terrain such that a line extending through the plurality of position indicators intersects the digital landmark, the position indicators being a fixed digital terrain distance apart as measured over the digital terrain.

Abstract: The present invention relates to a method for disrupting cells by subjecting the cells to ultrasonic energy in the absence of beads. The present invention also relates to the enhancement of cell disruption methods using ultrasonic energy by reducing the surface tension of the liquid in which the cells are located.

Abstract: On a data input device having a keypad with small, closely spaced buttons, an anchor is located on a panel section mountable proximate, and in fixed relation to, the keypad so that a user can reach the buttons while stabilizing their hand with the anchor.

Abstract: The present invention relates to a method for reducing the amount of substances inhibitory to nucleic acid hybridization in samples. The method is practiced prior to release of target nucleic acid from cells of interest and involves contacting the sample with an agent which solubilizes the inhibitory substances and does not effectuate release of nucleic acids from cells in the sample, and then the cells from the agent.

Abstract: The present invention relates to kits and methods for conducting fluorescence based detection assays. The kits are configured in a manner to perform the method so as to reduce or eliminate interfering fluorescence signal.

Abstract: Methods employing internal oligonucleotide standards in isothermal nucleic acid amplification reactions to determine the efficacy of the amplification reaction and to quantify pre-amplification target levels.

Abstract: The present invention relates to a method for reducing the amount of substances inhibitory to nucleic acid hybridization in samples. The method is practiced prior to release of target nucleic acid from cells of interest and involves contacting the sample with an agent which solubilizes the inhibitory substances and does not effectuate release of nucleic acids from cells in the sample, and then the cells from the agent.

Abstract: Strand Displacement Amplification methods (thermophilic SDA) which can be performed over a broad temperature range (37.degree. C. to 70.degree. C.). The preferred temperature range for thermophilic SDA is 50.degree. C. to 70.degree. C. It has been found that certain thermophilic restriction endonucleases are capable of nicking the hemimodified restriction endonuclease recognition/cleavage site as required by SDA and dissociating from the site. It has further been found that certain thermophilic polymerases are capable of extending from the nick while displacing the downstream strand. Thermophilic SDA, because of reaction temperatures higher than previously possible with conventional SDA enzyme systems, has improved specificity and efficiency, reduced nonspecific background amplification, and potentially improved yields of amplification products.

Abstract: Methods for using reporter mycobacteriophage (RM) and p-nitro-.alpha.-acetylamino-.beta.-hydroxy-propiophenone (NAP) to identify TB complex mycobacteria and distinguish these species from MOTT. RM-infected MOTT show little or no reduction in signal when treated with NAP. In contrast, TB complex mycobacteria infected with RM are distinguishable from RM-infected MOTT by a reduction in signal with NAP treatment.

Abstract: Strand Displacement Amplification methods (thermophilic SDA) which can be performed over a broad temperature range (37.degree. C. to 70.degree. C.). The preferred temperature range for thermophilic SDA is 50.degree. C. to 70.degree. C. It has been found that certain thermophilic restriction endonucleases are capable of nicking the hemimodified restriction endonuclease recognition/cleavage site as required by SDA and dissociating from the site. It has further been found that certain thermophilic polymerases are capable of extending from the nick while displacing the downstream strand. Thermophilic SDA, because of reaction temperatures higher than previously possible with conventional SDA enzyme systems, has improved specificity and efficiency, reduced nonspecific background amplification, and potentially improved yields of amplification products.

Abstract: Mycobacteriophage DS6A has been characterized and found to specifically infect all species of the TB complex, without any detectable infection of mycobacteria species other than those of the TB complex. DNA sequence analysis revealed several potential open reading frames, including one encoding a protein analogous to gp37 of mycobacteriophage L5 and a second encoding a protein with significant homology to the S. coelicolor DNA polymerase .beta. subunit. Based on the DNA sequence analysis, cloning sites can be identified for insertion of reporter genes, making DS6A useful as a reporter phage for specific detection and identification of species of the TB complex.

Abstract: Methods for multiplex amplification of target nucleic acid sequences using a single pair of primers. Defined sequences are appended to the ends of multiple target sequences as part of the amplification reaction so that no steps in addition to amplification are required. The target sequences with the appended defined sequences need not be isolated prior to amplification. In one embodiment for coamplification of two target sequences, a sequence corresponding to a terminal segment of the first target sequence is appended to one end of the second target sequence and a sequence corresponding to a terminal segment of the second target sequence is appended to one end of the first target sequence. Amplification of the two targets then requires only a single pair of primers. Alternatively, a single defined sequence may be appended to the 5' and 3' ends of any number of selected targets. All such modified target sequences may then be amplified using a single pair of primers which hybridize to the defined end-sequences.