Patents by Inventor Michael C. To

Michael C. To has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DRY EYE TREATMENT DEVICE
    Publication number: 20190350750
    Abstract: A dry eye treatment device and method of use are disclosed for applying heat to the exterior surface of an eyelid to treat dry eye symptoms which can be caused by meibomian gland dysfunction (MGD). More specifically, a user operable main unit and hand piece are provided that allow the user to heat his/her or another patient's eyelids to a desired temperature, which can effectively and efficiently raise the temperature at the meibomian glands sufficient to melt, loosen, or soften more serious occlusions or obstructions in the meibomian glands, thereby restoring natural secretory function to obstructed glands.
    Type: Application
    Filed: November 6, 2018
    Publication date: November 21, 2019
    Inventors: Michael C. Whitehurst, Michael Lutz
  • Long-Range Voice and Data Transmission Using LoRa Modulation and Sensitivity-Enhancing Buffering Techniques
    Publication number: 20190357079
    Abstract: Systems and methods are disclosed for extending the communication range of mobile communication devices. A long-range radio device is controlled by a control application on a host smartphone. The long-range radio device provides signal paths for two different radios, one employing a long-range (LoRa) modulation format, and another employing a high data-rate encoding such as FSK. The system provides graceful degradation in data rate as radio link distance increases and received signal strength decreases. In addition to switching between radios, variable compression and buffering are used to adapt usage to supportable data rates. Voice, other audio, video, text, binary, and other data formats are supported, as also a wide range of co-resident host apps. Unidirectional and bidirectional links can be used.
    Type: Application
    Filed: June 3, 2019
    Publication date: November 21, 2019
    Applicant: Beartooth Radio, Inc.
    Inventors: Jefferson M. Jones, Andrew M. Wade, Nicholas G. Evans, Michael C. Monaghan, Justin A. Hogan
  • INVENTORY SYSTEM FOR A REFRIGERATOR APPLIANCE
    Publication number: 20190353421
    Abstract: An inventory system for a refrigerator appliance includes an inventory plate which is operably coupled to a load cell and positioned within a chilled chamber. The inventory plate may be a fixed shelf or a portable coaster on which food items may be placed. A controller is configured for monitoring a weight of the food items over time using the load cell and/or a moisture content using a moisture sensor and providing an indication of food quality based at least in part on the weight and/or moisture content of the food items.
    Type: Application
    Filed: May 18, 2018
    Publication date: November 21, 2019
    Inventors: Brent Alden Junge, John Keith Besore, Michael C. Watanabe
  • B-CELL ENGINEERING
    Publication number: 20190352614
    Abstract: Described herein are constructs used for B-cell genomic engineering and for expression of a transgene and/or for modulation of B cell function.
    Type: Application
    Filed: January 25, 2018
    Publication date: November 21, 2019
    Inventors: Rainier Amora, Michael C. Holmes, Brigit E. Riley
  • METHODS AND COMPOSITIONS FOR NUCLEASE-MEDIATED TARGETED INTEGRATION
    Publication number: 20190352671
    Abstract: Disclosed herein are methods and compositions for targeted, nuclease-mediated insertion of transgene sequences into the genome of a cell.
    Type: Application
    Filed: August 5, 2019
    Publication date: November 21, 2019
    Inventors: Michael C. Holmes, Thomas Wechsler
  • INDOMETHACIN ANALOGS FOR THE TREATMENT OF CASTRATE-RESISTANT PROSTATE CANCER
    Publication number: 20190350903
    Abstract: Provided are compositions for inhibiting a biological activity of an aldo-keto reductase family 1, member C3 (AKR1C3) polypeptide. In some embodiments, the compositions are indomethacin derivatives that are AKR1C3-specific inhibitors. Also provided are methods for producing disclosed indomethacin derivatives that substantially lack cyclooxygenase inhibitory activity but that have AKR1C3 inhibitory activity, methods for inhibiting AKR1C3 polypeptide biological activities, and methods for treating prostate tumors in subjects.
    Type: Application
    Filed: August 2, 2019
    Publication date: November 21, 2019
    Applicants: Vanderbilt University, The Trustees of the University of Pennsylvania
    Inventors: Lawrence J. Marnett, Andy J. Liedtke, Trevor M. Penning, Adegoke O. Adeniji, Michael C. Byrns
  • Low-profile monopulse tracker
    Patent number: 10481253
    Abstract: A monopulse tracker includes multiple dual-axis monopulse antenna systems that are angled with respect to one another. The orientations of the monopulse antenna systems create a much larger field of view for the monopulse tracker to eliminate the need to steer the monopulse tracker. The monopulse tracker can be configured to estimate a position of an object based on tracking information received from more than one monopulse antenna system therefore increasing the accuracy of the estimated position. The multiple monopulse antenna systems can be arranged in a low-profile housing to facilitate use of the monopulse tracker on aircraft.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: November 19, 2019
    Assignee: L-3 Communications Corp.
    Inventors: Michael C Hollenbeck, Sy Prestwich, Jeffrey B Bench
  • Nested bellows pump and hybrid downhole pumping system employing same
    Patent number: 10480501
    Abstract: A nested bellows pump including a housing having a first end and a second end, the housing having a cylindrical body, the cylindrical body having an inner wall; a traveling bulkhead, the traveling bulkhead sealingly positionable along the inner wall of the cylindrical body; a first inner bellows, the first inner bellows connected to the housing, and the second bellows is connected to the traveling bulkhead; a second inner bellows connected to the traveling bulkhead, and the second end of the second inner bellows is connected to the housing; a first outer bellows connected to the housing, and the second end of the first outer bellows is connected to the traveling bulkhead; and a second outer bellows connected to the traveling bulkhead, and the second end of the second outer bellows is connected to the second end of the housing.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: November 19, 2019
    Assignee: ExxonMobil Upstream Research Company
    Inventors: Randy C Tolman, Michael C. Romer
  • Hydrocarbon wells and methods cooperatively utilizing a gas lift assembly and an electric submersible pump
    Patent number: 10480297
    Abstract: Hydrocarbon wells and methods cooperatively utilizing a gas lift assembly and an electric submersible pump, the hydrocarbon wells including a wellbore extending between a surface region and a subterranean formation, a downhole tubular defining a tubular conduit and extending within the wellbore, an electric pumping assembly, an electric power source, and a gas lift assembly. The methods include generating a pumped reservoir fluid stream, generating a gas lifted reservoir fluid stream, conveying the pumped reservoir fluid stream to a surface region via an ESP conduit, and conveying the gas lifted reservoir fluid stream to the surface region via an annular space that is distinct from the ESP conduit.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: November 19, 2019
    Assignee: ExxonMobil Upstream Research Company
    Inventors: Jessica I. Chidi, Michael C. Romer
  • System and method for arranging an order
    Patent number: 10482401
    Abstract: A method includes obtaining, by a management module, an inventory unpacking sequence for a remote facility. The inventory unpacking sequence indicates a sequence for unpacking a shipment at the remote facility. An order associated with the remote facility is received that includes inventory items. The management module determines an order packing arrangement for the inventory items based on the inventory unpacking sequence. Mobile drive units are instructed to transport one or more inventory holders storing the inventory items to an inventory station, where the inventory items are packed into a shipment according to the order packing arrangement. The shipment is arranged to be unpacked at the remote facility according to the inventory unpacking sequence.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: November 19, 2019
    Assignee: Amazon Technologies, Inc.
    Inventors: Peter R. Wurman, Michael C. Mountz, Daniel T. Brunner, Victoria M. Eddy, Zhouzhou Peng
  • Methods to store transition metal organophosphorous ligand based catalysts
    Patent number: 10478812
    Abstract: The catalyst solution used in a hydroformylation process is prepared for storage by first reducing its acid concentration and/or water content, and then storing the solution under a blanket of syngas and/or an inert gas. Alternatively, or in addition to, the catalyst solution can be stored with an aqueous buffer comprising materials that will neutralize and/or absorb the acid species within the catalyst solution.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: November 19, 2019
    Assignees: Dow Technology Investments LLC, BASF SE
    Inventors: Thomas C. Eisenschmid, Michael C. Becker, Donald L. Campbell, Jr., Michael A. Brammer, Glenn A. Miller, Edward Adrian Lord, Jens Rudolph, Hans-Rüdiger Reeh
  • Dynamic lacing system
    Patent number: 10477912
    Abstract: An article of footwear includes an upper defining an interior void and a first cable movable in a tightening direction to move the upper into a tightened state and movable in a loosening direction to move the upper into a loosened state. The article of footwear also includes a tightening grip operable to be moved away from the upper in a first direction to move the first cable in the tightening direction and a cable lock operable in a locked state to restrict movement of the first cable in the loosening direction and operable in an unlocked state to permit movement of the first cable in the loosening direction. A release grip is operable to be moved away from the upper in a second direction to move the cable lock from the locked state to the unlocked state, whereby the release grip is separate from the tightening grip.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: November 19, 2019
    Assignee: NIKE, Inc.
    Inventors: Caleb W. Dyer, Peter Lam, Austin Orand, Andrea M. Vinet, Peter P. Williams, II, Samantha Young, Michael C. Makay
  • Phase aligning phase locked loop (PLL) circuit
    Patent number: 10483986
    Abstract: A signal phase aligning system includes a signal generator configured to generate a signal. The system further includes a phase locked loop circuit configured to generate a phase locked loop signal based on the signal generated by the signal generator. The system includes a phase aligning circuit configured to align a phase of the phase locked loop signal with a phase of the signal generated by the signal generator.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: November 19, 2019
    Assignee: ROCKWELL COLLINS, INC.
    Inventors: Michael C. Meholensky, Robert D. Pond
  • Environmental control for medium-voltage drive
    Patent number: 10485146
    Abstract: In accordance with presently disclosed embodiments, a system and method for controlling the temperature of medium-voltage power electronics assemblies (i.e., medium-voltage drives) is provided. The disclosed system generally includes a medium-voltage drive having one or more cabinets with power electronics devices disposed therein, one or more fans for circulating air through the cabinet to cool the devices, and one or more space heaters disposed in the cabinet. The drive also features temperature sensors used to measure various temperatures of the drive, a controller communicatively coupled to the sensors, and one or more variable frequency drives (VFD) for the fans. The controller may receive measurements regarding the ambient and power device temperatures and apply controls to vary the space heater power and fan speed in response to environmental changes.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: November 19, 2019
    Assignee: Toshiba International Corporation
    Inventors: Michael C. Daskalos, John D. Kleinecke
  • Configurable vehicle seat and method therefor
    Patent number: 10481588
    Abstract: A conformal seat insert for an adjustable vehicle seat, the conformal seat insert comprising an insert frame, the insert frame having one or more insert reference features for locating the insert frame on a seat frame of the vehicle seat in a predetermined position relative to the seat frame, and a contoured support surface formed in the insert frame, the contoured support surface having a crew reference point corresponding to an acromial point of a shoulder of a seat occupant of the adjustable vehicle seat, the crew reference point being a datum from which an eye position of the seat occupant is established relative to instrumentation of an aerospace vehicle in which the adjustable vehicle seat is located.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: November 19, 2019
    Assignee: The Boeing Company
    Inventors: Michael C. McCarley, Christopher Ferguson
  • Multilayer articles comprising a release surface and methods thereof
    Patent number: 10479067
    Abstract: Described herein is multilayer article made by the process comprising: delivering particles comprising a silicon compound from at least one fluid jet to a metal surface to embed the metal surface with the silicon compound to form a silicon compound layer; coating the silicon compound layer with an aqueous fluoropolymer dispersion to form a fluoropolymer layer and thereby forming a multilayered article, wherein the aqueous fluoropolymer dispersion comprises (i) a modifying agent; and (ii) a fluorinated polymer, wherein the fluorinated polymer comprises at least one of (a) a partially fluorinated polymer capable of forming a carbon-carbon double bond, (b) a functionalized fluorinated polymer, and (c) combinations thereof; and sintering the multilayered article to form the release surface coated substrate.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: November 19, 2019
    Assignee: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Peter Bissinger, Michael C. Dadalas, Philipp Doebert, Rainer A. Guggenberger, Klaus Hintzer, Tilman C. Zipplies
  • Materials for near field transducers and near field transducers containing same
    Patent number: 10482914
    Abstract: A device including a near field transducer, the near field transducer including gold (Au) and at least one other secondary atom, the at least one other secondary atom selected from: boron (B), bismuth (Bi), indium (In), sulfur (S), silicon (Si), tin (Sn), hafnium (Hf), niobium (Nb), manganese (Mn), antimony (Sb), tellurium (Te), carbon (C), nitrogen (N), and oxygen (O), and combinations thereof; erbium (Er), holmium (Ho), lutetium (Lu), praseodymium (Pr), scandium (Sc), uranium (U), zinc (Zn), and combinations thereof; and barium (Ba), chlorine (Cl), cesium (Cs), dysprosium (Dy), europium (Eu), fluorine (F), gadolinium (Gd), germanium (Ge), hydrogen (H), iodine (I), osmium (Os), phosphorus (P), rubidium (Rb), rhenium (Re), selenium (Se), samarium (Sm), terbium (Tb), thallium (Th), and combinations thereof.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: November 19, 2019
    Assignee: Seagate Technology LLC
    Inventors: Yuhang Cheng, Tong Zhao, Michael C. Kautzky, Ed F. Rejda, Kurt W. Wierman, Scott Franzen, Sethuraman Jayashankar, Sarbeswar Sahoo, Jie Gong, Michael Allen Seigler
  • QUANTUM DOTS WITH STABILZING FLUOROCHEMICAL COPOLYMERS
    Publication number: 20190345378
    Abstract: Disclosed are quantum dots and quantum dot articles stabilized by a fluorochemical copolymer having pendent arsine, stibine or phosphine stabilizing groups; and pendent fluorochemical groups
    Type: Application
    Filed: February 9, 2017
    Publication date: November 14, 2019
    Inventors: Paul B. ARMSTRONG, Saswata CHAKRABORTY, Michael C. PALAZZOTTO
  • SUBLINGUAL OR BUCCAL ADMINISTRATION OF DIM FOR TREATMENT OF SKIN DISEASES
    Publication number: 20190343798
    Abstract: Described herein are methods for treating one or more skin conditions by administering, via the sublingual or buccal route, a composition comprising substituted or unsubstituted diindolylmethane. In particular, methods are provided for improving the bioavailability and pharmacokinetic parameters of substituted or unsubstituted diindolylmethane following a sublingual or buccal administration, relative to an oral administration.
    Type: Application
    Filed: September 15, 2017
    Publication date: November 14, 2019
    Inventor: Michael C. SCAIFE
  • DOPAMINE D2 RECEPTOR LIGANDS
    Publication number: 20190345105
    Abstract: The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity.
    Type: Application
    Filed: December 18, 2015
    Publication date: November 14, 2019
    Applicants: The Broad Institute, Inc., Massachusetts Institute of Technology
    Inventors: Edward Holson, Florence Fevrier Wagner, Michel Weiwer, Edward Scolnick, Michelle Palmer, Michael C. Lewis, Jennifer Q. Pan, Yan-Ling Zhang, Qihong Xu