Patents by Inventor Michael C. Vander Zwan

Michael C. Vander Zwan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of 9-(2,6-dihalobenzyl)adenines
    Patent number: 4100159
    Abstract: 9-(2,6-Dihalobenzyl)adenines are prepared by allowing 2,6-dihalobenzyl halides to react with a salt of adenine in a solid-liquid or liquid-liquid two phase system in the presence of an onium salt phase transfer catalyst. The resulting compounds have anticoccidial activity and are useful in controlling cecal and/or intestinal coccidiosis when administered in minor quantities to animals, in particular to poultry usually in admixture with animal sustenance.
    Type: Grant
    Filed: February 7, 1977
    Date of Patent: July 11, 1978
    Assignee: Merck & Co., Inc.
    Inventor: Michael C. Vander Zwan
  • Preparation of 4,6-diamino-5-arylazopyrimidines and adenine compounds
    Patent number: 4092314
    Abstract: The present invention relates to a novel and useful process for preparing 4,6-diamino-5-arylazopyrimidine from an arylazomalononitrile in the presence of ammonium chloride and formamide. If desired, the 4,6-diamino-5-arylazopyrimidine may then be hydrogenated to form 4,5,6-triaminopyrimidine which, when the hydrogenation is carried out in the presence of formic acid or its derivative, gives adenine.
    Type: Grant
    Filed: October 18, 1976
    Date of Patent: May 30, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Michael C. Vander Zwan, Donald F. Reinhold