Patents by Inventor Michael Carleton

Michael Carleton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11893109
    Abstract: A method, a system, and a computer program product for protection and recovery of backup storage systems from ransomware attacks. A request to modify data stored in a storage system is received. The storage system includes at least one component configured to store the deduplicated data. An acknowledgement of the received request is generated. The acknowledgement indicates that the data stored in the at least one component and identified in the received request was modified. Modification of the data stored in the at least one component and identified in the received request for a predetermined period of time is prevented.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: February 6, 2024
    Assignee: Exagrid Systems, Inc.
    Inventors: Alex Pientka, Michael Carleton, Adrian T. VanderSpek, Stephen Smith, Luke Makosky, Peter Watkins, Nathaniel W. Turner, Sandra C. Scott, Yee-Ching Chao, Thomas J. Gillispie, William Andrews, David G. Therrien, Jamey C. Poirier, Mark B. Hecker, Andrew H. French
  • Publication number: 20230416802
    Abstract: Provided are HSD17B13 substrates, reaction products, kits, and methods that include the HSD17B13 substrates or reaction products of the HSD17B13 substrates. Some embodiments include methods of treatment. Some such embodiments include determining an amount of an HSD17B13 substrate or of a reaction product of the HSD17B13 substrate in a sample from the subject to whom the HSD17B13 substrate has been administered.
    Type: Application
    Filed: November 3, 2021
    Publication date: December 28, 2023
    Inventors: Heather Kay Webb HSU, Vincent FLORIO, Michael CARLETON, Joshua ODINGO
  • Publication number: 20230279096
    Abstract: Provided herein are methods for the clinical treatment of tumors (e.g., advanced solid tumors) in patients having certain levels of serum IL-8 using an anti-IL-8 antibody in combination with an anti-PD-1 antibody.
    Type: Application
    Filed: December 29, 2022
    Publication date: September 7, 2023
    Inventors: Michael CARLETON, David FELTQUATE, Olivier DE HENAU, Timothy Patrick REILLY, Tian CHEN, Ye FENG, Shu-Pang Ben HUANG, Ming ZHOU, Ramachandran SURESH
  • Publication number: 20230192870
    Abstract: The present invention relates to methods of treating pancreatic cancer with particular dosage regimes of antibodies that bind colony stimulating factor 1 receptor (CSF1R) (e.g. cabiralizumab) in combination with antibodies that bind programmed cell death 1 (PD-1) (e.g. nivolumab).
    Type: Application
    Filed: July 14, 2022
    Publication date: June 22, 2023
    Applicants: Five Prime Therapeutics, Inc., Bristol-Myers Squibb Company
    Inventors: Katherine E. Lewis, Serena Kimi Perna, Michael Carleton, Ke Xu, Penny Phillips, Dimple Pandya, Brian Wong, Julie Hambleton, Robert Sikorski, Emma Masteller, Kevin Hestir, David Bellovin, Janine Powers, Ernestine Lee
  • Patent number: 11572405
    Abstract: Provided herein are methods for the clinical treatment of tumors (e.g., advanced solid tumors) in patients having certain levels of serum IL-8 using an anti-IL-8 antibody in combination with an anti-PD-1 antibody.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: February 7, 2023
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael Carleton, David Feltquate, Olivier De Henau, Timothy Patrick Reilly, Tian Chen, Ye Feng, Shu-Pang Ben Huang, Ming Zhou, Ramachandran Suresh
  • Patent number: 11517831
    Abstract: An abatement system for pyrophoric chemicals where the materials are captured or controlled by a hazard volume and fed to a vaporizer in an oxygen deprived environment. Materials are heated until vaporized while mixed with nitrogen. The mixture exits the system through a reaction column. The system is monitored by oxygen sensors, smoke detectors and temperature sensors.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: December 6, 2022
    Inventors: George Andrew Rabroker, Michael Carleton Murphey
  • Patent number: 11421034
    Abstract: The present invention relates to methods of treating pancreatic cancer with particular dosage regimes of antibodies that bind colony stimulating factor 1 receptor (CSF1R) (e.g. cabiralizumab) in combination with antibodies that bind programmed cell death 1 (PD-1) (e.g. nivolumab).
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: August 23, 2022
    Assignees: Five Prime Therapeutics, Inc., Bristol-Myers Squibb Company
    Inventors: Katherine E. Lewis, Serena Kimi Perna, Michael Carleton, Ke Xu, Penny Phillips, Dimple Pandya, Brian Wong, Julie Hambleton, Robert Sikorski, Emma Masteller, Kevin Hestir, David Bellovin, Janine Powers, Ernestine Lee
  • Patent number: 11279912
    Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria, that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: March 22, 2022
    Assignee: LUMEN BIOSCIENCE, INC.
    Inventors: James Roberts, Michael Carleton, Damian Carrieri, Jason W. Hickman
  • Publication number: 20210224379
    Abstract: A method, a system, and a computer program product for protection and recovery of backup storage systems from ransomware attacks. A request to modify data stored in a storage system is received. The storage system includes at least one component configured to store the deduplicated data. An acknowledgement of the received request is generated. The acknowledgement indicates that the data stored in the at least one component and identified in the received request was modified. Modification of the data stored in the at least one component and identified in the received request for a predetermined period of time is prevented.
    Type: Application
    Filed: January 15, 2021
    Publication date: July 22, 2021
    Inventors: Alex Pientka, Michael Carleton, Adrian T. VanderSpek, Stephen Smith, Luke Makosky, Peter Watkins, Nathaniel W. Turner, Sandra C. Scott, Yee-ching Chao, Thomas J. Gillispie, William Andrews, David G. Therrien, Jamey C. Poirier, Mark B. Hecker, Andrew H. French
  • Publication number: 20210054063
    Abstract: Provided herein are methods for the clinical treatment of tumors (e.g., advanced solid tumors) in patients having certain levels of serum IL-8 using an anti-IL-8 antibody in combination with an anti-PD-1 antibody.
    Type: Application
    Filed: January 11, 2019
    Publication date: February 25, 2021
    Inventors: Michael CARLETON, David FELTQUATE, Olivier DE HENAU, Timothy Patrick REILLY, Tian CHEN, Ye FENG, Shu-Pang Ben HUANG, Ming ZHOU, Ramachandran SURESH
  • Publication number: 20210047610
    Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria, that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
    Type: Application
    Filed: August 21, 2020
    Publication date: February 18, 2021
    Inventors: James ROBERTS, Michael CARLETON, Damian CARRIERI, Jason W. HICKMAN
  • Publication number: 20210009697
    Abstract: The present invention relates to methods of treating pancreatic cancer with particular dosage regimes of antibodies that bind colony stimulating factor 1 receptor (CSF1R) (e.g. cabiralizumab) in combination with antibodies that bind programmed cell death 1 (PD-1) (e.g. nivolumab).
    Type: Application
    Filed: September 12, 2018
    Publication date: January 14, 2021
    Applicants: Five Prime Therapeutics, Inc., Bristol-Myers Squibb Company
    Inventors: Katherine E. Lewis, Serena Kimi Perna, Michael Carleton, Ke Xu, Penny Phillips, Dimple Pandya, Brian Wong, Julie Hambleton, Robert Sikorski, Emma Masteller, Kevin Hestir, David Bellovin, Janine Powers, Ernestine Lee
  • Publication number: 20200406162
    Abstract: An abatement system for pyrophoric chemicals where the materials are captured or controlled by a hazard volume and fed to a vaporizer in an oxygen deprived environment. Materials are heated until vaporized while mixed with nitrogen. The mixture exits the system through a reaction column. The system is monitored by oxygen sensors, smoke detectors and temperature sensors.
    Type: Application
    Filed: June 25, 2019
    Publication date: December 31, 2020
    Applicant: Basis-Solutions, LLC
    Inventors: George Andrew Rabroker, Michael Carleton Murphey
  • Patent number: 10760045
    Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria, that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: September 1, 2020
    Assignee: LUMEN BIOSCIENCE, INC.
    Inventors: James Roberts, Michael Carleton, Damian Carrieri, Jason W. Hickman
  • Publication number: 20200246275
    Abstract: Provided are methods of treating a cancer (such as lung cancer, breast cancer, pancreatic cancer, etc.) in an individual in need thereof, comprising administering to the individual a) an effective amount of a composition comprising nanoparticles comprising a taxane (such as paclitaxel) and an albumin (such as human serum albumin), and b) an effective amount of ABT-263.
    Type: Application
    Filed: November 8, 2019
    Publication date: August 6, 2020
    Inventors: Daniel PIERCE, Michael CARLETON
  • Publication number: 20200172859
    Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria, that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
    Type: Application
    Filed: February 14, 2020
    Publication date: June 4, 2020
    Inventors: James ROBERTS, Michael CARLETON, Damian CARRIERI, Jason W. HICKMAN
  • Patent number: 10563168
    Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: February 18, 2020
    Assignee: LUMEN BIOSCIENCE, INC.
    Inventors: James Roberts, Michael Carleton, Damian Carrieri, Jason W. Hickman
  • Publication number: 20190093066
    Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
    Type: Application
    Filed: January 25, 2018
    Publication date: March 28, 2019
    Inventors: James ROBERTS, Michael CARLETON, Damian CARRIERI, Jason W. HICKMAN
  • Patent number: 9914907
    Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria, that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: March 13, 2018
    Assignee: LUMEN BIOSCIENCE, INC.
    Inventors: James Roberts, Michael Carleton, Damian Carrieri, Jason W. Hickman
  • Publication number: 20180051057
    Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria, that have a reduced amount of a light harvesting protein (LHP) polypeptide and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
    Type: Application
    Filed: September 15, 2015
    Publication date: February 22, 2018
    Inventors: James Roberts, Michael Carleton, Jason W. Hickman, Damian Carrieri, Mark Heinnickel