Abstract: An organ model comprises a polymer body formed from one or more selectively deposited substructures of a printable polymer-based ink composition, wherein the one or more selectively deposited substructures form a printed geometrical structure that corresponds to at least a portion of an anatomical structure of an organ, wherein a formulation of the printable polymer-based ink is selected such that the printed geometrical body has one or more material properties that match or substantially match one or more corresponding tissue material properties of an organ tissue, and an electronic device integrated onto a surface or into a structure of the printed geometrical structure.

Abstract: A system and method is provided for imaging and monitoring a tissue, such as a cerebral cortex, of a subject. Access to imaging a tissue, such as cerebral cortex, may be provided by removing a portion of a bone, such as a portion of a skull of the subject. A prosthesis, such as an optically transparent prosthesis, may be used to replace the portion of the skull removed and may be conformed to the same 3D contour of the bone that was removed. A data acquisition system, such as an imaging system, may then be affixed to the skull prosthesis and may be used to acquire image data of the tissue of the subject at high spatial and temporal resolution and without interference from intervening bone material.

Abstract: An organ model comprises a polymer body formed from one or more selectively deposited substructures of a printable polymer-based ink composition, wherein the one or more selectively deposited substructures form a printed geometrical structure that corresponds to at least a portion of an anatomical structure of an organ, wherein a formulation of the printable polymer-based ink is selected such that the printed geometrical body has one or more material properties that match or substantially match one or more corresponding tissue material properties of an organ tissue, and an electronic device integrated onto a surface or into a structure of the printed geometrical structure.