Abstract: The present disclosure is directed to systems and methods of multiphase pseudo-continuous arterial spin labeling.

Abstract: Described herein are methods and systems for partial volume estimation (PVE) and correction of PVE of imaging data acquired or provided of a subject, The imaging data can include functional imaging data, in particular functional imaging data acquired using magnetic resonance (MR), arterial spin labeling (ASL), blood-oxygen level dependent (BOLD) magnetic resonance imaging (MRI), or positron emission tomography (PET) of the subject.

Abstract: A method comprises: scanning a patient with a PET scanner; computing a patient myocardial blood flow (MBF) parameter value and a patient MBF variation value of the patient based on the scanning; comparing the patient MBF variation value to an MBF variation threshold; and determining that the patient MBF parameter value is unreliable in response to determining that the patient MBF variation value is greater than the MBF variation threshold.

Abstract: The present disclosure is directed to systems and methods of multiphase pseudo-continuous arterial spin labeling.

Abstract: Disclosed are systems, compositions, and methods for three-dimensional (3D) printing. An example system includes a plurality dispensers configured to deposit materials from their tips and a printing surface for receiving the materials. The system includes a position sensing detector configured to detect positions of the tips of the dispensers and the location and dimensions of the printing surface. The system includes a robotic positioning device configured to drive the dispensers. The system also includes a control unit configured to receive and map in a 3D space the positions of the tips of the dispensers and the position and dimensions of the printing surface. The control unit is further configured to control the robotic positioning device to drive the dispensers relative to the printing surface in the 3D space, and to independently deposit materials on the printing surface, or on material deposited on the printing surface.

Abstract: Arterial spin labelling (ASL) MRI offers a non-invasive means to create blood-borne contrast in vivo for dynamic angiographic imaging. By spatial modulation of the ASL process it is possible to uniquely label individual arteries over a series of measurements, allowing each to be separately identified in the resulting images. This separation requires appropriate analysis for which a general framework has previously been proposed. Here the general framework is modified for fast analysis of non-invasive imaging of blood flow using vessel encoded arterial spin labelling (VE-ASL). This specifically addresses the issues of computational speed of the analysis and the robustness required to deal with real patient data. The modification applies various approaches for estimation of one or more parameters that change the way a vessel, for example an artery, is encoded to provide the fast analysis.

Abstract: A grow light system for producing a deep penetrating light source including a hood light fixture with an outer wall structure and an inner reflective panel configured to reflective light toward a light opening, the inner reflective panel having a first inner light reflecting panel and a second inner light reflecting panel and the first and second inner light reflective panels being on either side of a light fixture axis, the fixture including a first light source fixed relative to the first inner light reflecting panel and a second light source fixed relative to the second inner light reflecting panel, the first and second light inner light reflecting panels and the light opening having a generally triangular cross-section configuration transverse to the fixture axis wherein the first and second light reflective panels are oriented at a grow light angle from one another between 40 and 80 degrees.

Abstract: In an aspect, first intrinsic information relating to an event can be received in advance of a beginning of the event. First extrinsic information relating to the event can be received in advance of the beginning of the event. Second intrinsic information relating to the event can be received subsequent to the beginning of the event. Optionally, second extrinsic information relating to the event can be received subsequent to the beginning of the event. Impact metrics can be generated from the received first intrinsic information, the received first extrinsic information, the received second intrinsic information, and the received second extrinsic information. The generated impact metrics can be outputted.

Abstract: Systems and methods are disclosed for quantifying absolute blood volume flow rates by fitting a kinetic model incorporating blood volume, bolus dispersion and signal attenuation to dynamic angiographic data. A self-calibration method is described for both 2D and 3D data sets to convert the relative blood volume parameter into absolute units. The parameter values are then used to simulate the signal arising from a very short bolus, in the absence of signal attenuation, which can be readily encompassed within a vessel mask of interest. The volume flow rate can then be determined by calculating the blood volume within the vessel mask and dividing by the simulated bolus duration. This method is exemplified using non-contrast magnetic resonance imaging data from a flow phantom and the cerebral arteries of healthy volunteers and a patient with Moya-Moya disease acquired using a 2D vessel-encoded pseudo-continuous arterial spin labeling pulse sequence.

Abstract: Disclosed are systems, compositions, and methods for three-dimensional (3D) printing. An example system includes a plurality dispensers configured to deposit materials from their tips and a printing surface for receiving the materials. The system includes a position sensing detector configured to detect positions of the tips of the dispensers and the location and dimensions of the printing surface. The system includes a robotic positioning device configured to drive the dispensers. The system also includes a control unit configured to receive and map in a 3D space the positions of the tips of the dispensers and the position and dimensions of the printing surface. The control unit is further configured to control the robotic positioning device to drive the dispensers relative to the printing surface in the 3D space, and to independently deposit materials on the printing surface, or on material deposited on the printing surface.

Abstract: The invention provides a method of estimating free light chain production (FLC) in a subject comprising (i) determining an amount of FLC in a sample from the subject; and (ii) correcting the amount of FLC in the sample for FLC cleared from the source of the sample by glomerular filtration and by reticuloendothelial (RE) clearance.

Abstract: Economic conversion of lignocellulose requires both the maximization of conversion of available carbohydrates, as well as minimization of process capital cost. Process intensification minimizes capital cost while preserving conversion yield by combining into a single step those unit operations that are conducted at similar conditions. Flowsheet variations are proposed that minimize process capital while maintaining overall conversion yield.

Abstract: Arterial spin labelling (ASL) MRI offers a non-invasive means to create blood-borne contrast in vivo for dynamic angiographic imaging. By spatial modulation of the ASL process it is possible to uniquely label individual arteries over a series of measurements, allowing each to be separately identified in the resulting images. This separation requires appropriate analysis for which a general framework has previously been proposed. Here the general framework is modified for fast analysis of non-invasive imaging of blood flow using vessel encoded arterial spin labelling (VE-ASL). This specifically addresses the issues of computational speed of the analysis and the robustness required to deal with real patient data. The modification applies various approaches for estimation of one or more parameters that change the way a vessel, for example an artery, is encoded to provide the fast analysis.

Abstract: Systems and methods are disclosed for quantifying absolute blood volume flow rates by fitting a kinetic model incorporating blood volume, bolus dispersion and signal attenuation to dynamic angiographic data. A self-calibration method is described for both 2D and 3D data sets to convert the relative blood volume parameter into absolute units. The parameter values are then used to simulate the signal arising from a very short bolus, in the absence of signal attenuation, which can be readily encompassed within a vessel mask of interest. The volume flow rate can then be determined by calculating the blood volume within the vessel mask and dividing by the simulated bolus duration. This method is exemplified using non-contrast magnetic resonance imaging data from a flow phantom and the cerebral arteries of healthy volunteers and a patient with Moya-Moya disease acquired using a 2D vessel-encoded pseudo-continuous arterial spin labeling pulse sequence.

Abstract: Disclosed are personal cleansing compositions for rinse-off application to the hair, nails or skin. These compositions comprise a silicone-resin based adhesive including a silicone resin copolymer as a condensation product of an organosiloxane fluid and a silicone resin; a cleansing surfactant; and a carrier liquid. The personal cleansing compositions can also comprise as the silicone-resin based adhesive, in addition to or in place of the silicone resin copolymer, a combination of an organosiloxane resin and a diorganosiloxane fluid at a weight ratio of said resin to said fluid of from about 1:9 to about 10:1. The personal cleansing compositions provide hair styling benefits when applied to the hair, and when applied to the skin, barrier protection from surfactants or other materials having skin irritation potential.