Abstract: The present disclosure relates to a method for the production of an inner surface coating on an enclosed article, such as a capillary. the method comprising vaporizing a first monomer and reacting the vaporized first monomer with the inner surface of an enclosed article to provide a monomer layer on the inner surface of the enclosed article. Also disclosed are coated enclosed articles and apparatus for performing the method.

Abstract: A system for the separation and detection of inorganic anions in a sample, the system comprising: • a separation channel with an inner coating of three or more alternating layers of a cationic polymer (e.g. hexadimethine bromide) and an anionic polymer (e.g. polystyrene sulfonate), wherein the first layer and the final layer are cationic polymer layers; • a detector for detecting inorganic anions that pass through a detection zone of the separation channel; • an injection system for injecting fluids including sample solutions and background electrolyte into an inlet end of the separation channel; wherein the background electrolyte comprises polyethyleneimine. Also described are corresponding methods, separation capillaries and cartridges for use in the system.

Abstract: The present application relates to processes for modifying the distribution of a compound in a solution comprising drawing the solution comprising the compound into an electroseparation syringe comprising a syringe barrel, a plunger and electrodes positioned to apply a voltage across solution contained in the syringe barrel, and applying a voltage across the solution in the syringe barrel to modify the distribution of the compound within the solution contained in the syringe barrel. The process may be performed as a part of an analytical process.

Abstract: The present invention relates to an evaporative membrane concentration device adapted to interface two liquid flow processes, such as two low or high resolution separation techniques or a low or high resolution separation technique and a liquid flow detection technique. For example, the two liquid flow processes may be a liquid chromatography technique and a liquid flow detection technique or a multi-dimensional separation technique, for example, two dimensional liquid chromatography (LC×LC) or solvent extraction, such as liquid-liquid extraction or solid phase extraction, with a liquid chromatography technique (LLE or SPE-LC). Methods of using the device and separation and/or chromatographic methods using the device are also described.

Abstract: A system for the separation and detection of inorganic anions in a sample, the system comprising: a separation channel with an inner coating of three or more alternating layers of a cationic polymer (e.g. hexadimethine bromide) and an anionic polymer (e.g. polystyrene sulfonate), wherein the first layer and the final layer are cationic polymer layers; a detector for detecting inorganic anions that pass through a detection zone of the separation channel; an injection system for injecting fluids including sample solutions and background electrolyte into an inlet end of the separation channel; wherein the background electrolyte comprises polyethyleneimine. Also described are corresponding methods, separation capillaries and cartridges for use in the system.

Abstract: A device for extracting and concentrating a target analyte including a sample channel that receives the sample, a separation channel, a waste channel, a first junction between the sample channel and the separation channel, and, a second junction between the separation channel and the waste channel. The first junction selectively transports a first group of analytes, including target analytes, from the sample channel to the separation channel in accordance with a size of a first free transport region of the first junction. The second junction selectively transports a second group of analytes from the separation channel to the waste channel in accordance with a size of a second free transport region of the second junction, the second group being a subset of the first group, so as to concentrate a number of the target analytes in the separation channel.