Patents by Inventor Michael Charles Lloyd

Michael Charles Lloyd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF
    Publication number: 20190276470
    Abstract: The present application relate to process for preparation of tetrahydrofuran compound of formula II, 4-Methylene tetrahydrofuran compound of formula V and tetrahydropyran compound of formula IX which are useful as intermediates for the preparation of halichondrin B analogues such as Eribulin or its pharmaceutically acceptable salts.
    Type: Application
    Filed: November 23, 2017
    Publication date: September 12, 2019
    Inventors: Michael Charles LLOYD, Pallavi RAO, Vishnu Vardhana Vema Reddy EDA, Srinivas ORUGANTI, Kumar SARVESH, Debjit BASU, Raja gopal PENUMANDLA, Prapulla Kumar PALVAI, Amit Kumar MANDAL, Vilas Hareshwar DAHANUKAR, Graham Andrew MEEK, Sarah Ann WARREN, Martin Edward FOX, Robert Wen Ming DAVIDSON
  • Preparation of (3aS,7aR)-hexahydroisobenzofuran-1(3H)-one by catalyzed biological resolution of dimethyl cyclohexane-1,2-dicarboxylate
    Patent number: 9080193
    Abstract: Processes for the synthesis of (3aS,7aR)-hexahydroisobenzofuran-1-(3H)-one, comprising comprising enzymatic hydrolysis of dimethyl cyclohexane-1,2-dicarboxylate to form (1S,2R)-2-(methoxycarbonyl) cyclohexanecarboxylic acid. The enzyme can be from a non-mammalian source.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: July 14, 2015
    Assignee: AbbVie Inc.
    Inventor: Michael Charles Lloyd
  • PREPARATION OF (3aS,7aR)-HEXAHYDROISOBENZOFURAN-1(3H)-ONE BY CATALYZED BIOLOGICAL RESOLUTION OF DIMETHYL CYCLOHEXANE-1,2-DICARBOXYLATE
    Publication number: 20130273618
    Abstract: Processes for the synthesis of (3aS,7aR)-hexahydroisobenzofuran-1-(3H)-one, comprising comprising enzymatic hydrolysis of dimethyl cyclohexane-1,2-dicarboxylate to form (1S,2R)-2-(methoxycarbonyl) cyclohexanecarboxylic acid. The enzyme can be from a non-mammalian source.
    Type: Application
    Filed: May 24, 2011
    Publication date: October 17, 2013
    Applicant: Abbott Products Operations AG
    Inventor: Michael Charles Lloyd