Patents by Inventor Michael CHARLTON

Michael CHARLTON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11802110
    Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 2-amino-N-(arylsulfinyl)-acetamide compounds that, inter alia, inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase (aaRS) (e.g., bacterial leucyl-t RNA synthetase, LeuRS). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase; to treat disorders that are ameliorated by the inhibition (e.g., selective inhibition) of bacterial aminoacyl-tRNA synthetase; to treat bacterial infections; etc.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: October 31, 2023
    Assignee: Oxford Drug Design Limited
    Inventors: Paul William Finn, Michael Charlton, Grace Edmund, Aigars Jirgensons, Einars Loza
  • Patent number: 11072581
    Abstract: The present invention relates to novel N-acyl-diarysulfonamides acting as inhibitors of bacterial aminoacyl-tRNA synthetase. These can be used as medicines or as constituent of medicines for the treatment of bacterial infections.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: July 27, 2021
    Assignee: Oxford Drug Design Limited
    Inventors: Aigars Jirgensons, Einars Loza, Michael Charlton, Paul William Finn, Lluis Ribas De Pouplana, Adelaide Saint-Léger
  • Publication number: 20200039929
    Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 2-amino-N-(arylsulfinyl)-acetamide compounds that, inter alia, inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase (aaRS) (e.g., bacterial leucyl-t RNA synthetase, LeuRS). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase; to treat disorders that are ameliorated by the inhibition (e.g., selective inhibition) of bacterial aminoacyl-tRNA synthetase; to treat bacterial infections; etc.
    Type: Application
    Filed: October 6, 2017
    Publication date: February 6, 2020
    Inventors: Paul William FINN, Michael CHARLTON, Grace EDMUND, Aigars JIRGENSONS, Einars LOZA
  • Publication number: 20180022696
    Abstract: The present invention relates to novel N-acyl-diarysulfonamides acting as inhibitors of bacterial aminoacyl-tRNA synthetase. These can be used as medicines or as constituent of medicines for the treatment of bacterial infections.
    Type: Application
    Filed: February 11, 2016
    Publication date: January 25, 2018
    Inventors: Aigars JIRGENSONS, Einars LOZA, Michael CHARLTON, Paul William FINN, Lluis RIBAS DE POUPLANA, Adelaide SAINT-LÉGER
  • Publication number: 20150333973
    Abstract: Method, system and application for controlling a program executing within a server from a mobile device. Capturing information describing a user interaction with a user interface of the mobile device. Determining a next user interaction based on the captured information and data describing the user interface. Triggering an event corresponding to the determined next user interaction.
    Type: Application
    Filed: May 15, 2015
    Publication date: November 19, 2015
    Inventors: Federico BOCCARDI, Ralf IRMER, Michael CHARLTON
  • Patent number: 9131821
    Abstract: A hand utility interface (1) as illustrated in figure (1) has a medially symmetric body providing two lateral finger channels (2a) and two medial finger channels (2b) extending from a palm part (8) whereby it can be used by either left or right hand. The interface (1) is fabricated from a thin self supporting resilient membrane so that when the fingers of a hand “H” are pressed down into the finger channels (2a, 2b) the interface gently grips the fingers thereby attaching itself to the hand for use. The interface is sufficiently flexible to reflect the flexure of the fingers of the hand “H”. The structure of the interface is such that extension and spreading of the fingers effects single handed discarding of the interface.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: September 15, 2015
    Inventors: Michael Charlton Powell, Leslie James Stokes, Rudolf Kautz
  • Publication number: 20120071070
    Abstract: The present invention provides, inter alia, a hand utility interface comprising a body having a plurality of finger members or channels each sized and shaped to receive one finger of the user's hand, wherein the user's hand is releasably gripped by the hand utility interface when the fingers of the hand are inserted into the members or channels, the interface having a finger tip-receiving recess formed therein in the upper surface thereof at a location that is proximate a front edge/distal end of the hand utility interface substantially forward of at least one of the finger members or channels whereby the user may insert a finger tip into the recess to press the hand utility interface down firmly against a target surface at the front/distal end of the hand utility interface. This arrangement enhances control when the device is used to sand or otherwise treat surfaces of target objects in corners/regions that are otherwise enclosed and awkward to access.
    Type: Application
    Filed: February 19, 2010
    Publication date: March 22, 2012
    Inventors: Michael Charlton Powell, Leslie James Stokes
  • Publication number: 20120000001
    Abstract: The present invention provides a hand-utility interface for use in protecting a user's hand during utility tasks and comprising a body having a plurality of finger-receiving channels defined therein, wherein the finger-receiving channels snugly receive the fingers of said user's hand such that in use, the finger-receiving channels secure the interface to the user's hand. Additional palm supports may be provided too if desired.
    Type: Application
    Filed: February 14, 2011
    Publication date: January 5, 2012
    Inventors: Michael Charlton Powell, Leslie James Stokes
  • Publication number: 20090207052
    Abstract: A hand utility interface (1) as illustrated in figure (1) has a medially symmetric body providing two lateral finger channels (2a) and two medial finger channels (2b) extending from a palm part (8) whereby it can be used by either left or right hand. The interface (1) is fabricated from a thin self supporting resilient membrane so that when the fingers of a hand “H” are pressed down into the finger channels (2a, 2b) the interface gently grips the fingers thereby attaching itself to the hand for use. The interface is sufficiently flexible to reflect the flexure of the fingers of the hand “H”. The structure of the interface is such that extension and spreading of the fingers effects single handed discarding of the interface.
    Type: Application
    Filed: July 6, 2007
    Publication date: August 20, 2009
    Inventors: Michael Charlton Powell, Leslie James Stokes, Rudolf Kautz
  • Publication number: 20080276395
    Abstract: There is provided a hand-utility interface for use in protecting a user's hand during utility tasks. The interface comprises a foamed block body having a plurality of finger-receiving channels defined therein, wherein each finger-receiving channel snugly receives a finger of said user's hand such that in use, the finger-receiving channels secure the interface to the user's hand. The foamed block body comprises at least two finger-channels of equal length for receipt of the second and third fingers of the user's hand respectively, thereby enabling its ready alternate use by either the left or right hand of the user.
    Type: Application
    Filed: June 22, 2005
    Publication date: November 13, 2008
    Applicant: Switchkey Intellectual Property Limited
    Inventors: Michael Charlton Powell, Leslie James Stokes
  • Publication number: 20040148675
    Abstract: There is provided a glove-like interface for use in protecting a user's hand during utility tasks comprising a body having a plurality of finger members extending therefrom; and resilient hand support means for securing the glove to a user's hand, wherein the resilient hand support means comprises both finger support means and palm support means for respectively securing the glove to the fingers and palm of the user's hand.
    Type: Application
    Filed: March 31, 2004
    Publication date: August 5, 2004
    Inventor: Michael Charlton Powell