Patents by Inventor Michael Christoph

Michael Christoph has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240123418
    Abstract: The invention relates to an apparatus for analyzing reaction systems with a liquid phase (13) and a gas phase (15), the apparatus (1) comprising at least two tank reactors (3), a common feed line (5), a common drain line (25) for the liquid phase and a common drain line (21) for the gas phase, each tank reactor (3) being connected to the common feed line (5) by a supply line (7), to the common drain line (25) for the liquid phase by a liquid withdrawal line (27) and to the common drain line (21) for the gas phase by a gas withdrawal line (23), wherein the pressure in each tank reactor (3) is controlled by one of: (a) a pressure control (31) in the common feed line (5); (b) a pressure line (29) which is connected to the gas space of each tank reactor (3); (c) a pressure control (31) in the common drain line (21) for the gas phase and a flow restrictor (33) in the common drain line (25) for the liquid phase or a pressure control (31) in the common drain line (25) for the liquid phase and a flow restrictor (3
    Type: Application
    Filed: March 4, 2022
    Publication date: April 18, 2024
    Inventors: Andreas Mueller, Peter Kolb, Michael Dejmek, Max Christoph Schmid
  • Patent number: 11958810
    Abstract: Preparation of optionally substituted dihydroisoquinolines. The present invention relates to a process for the preparation of optionally substituted dihydroi-soquinolines of the formula I.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: April 16, 2024
    Assignee: BASF SE
    Inventors: Bernd Mueller, Michael Rack, Michael Seet, Ana Escribano Cuesta, Jan Klaas Lohmann, Georg Christoph Rudolf, Markus Nett, Rainer Hoffmann
  • Patent number: 9297806
    Abstract: The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions useful for diagnosing or predicting cancer in a patient. In one embodiment, a method for identifying a patient as having cancer comprises the steps of (a) providing a formalin-fixed, paraffin-embedded or fresh frozen sample of patient tissue; (b) steaming the sample in antigen retrieval buffer; (c) incubating the sample in hydrochloric acid (HCl); (d) incubating the sample with an affinity reagent specific for 5hmC under conditions to form a complex between the affinity reagent and 5-hydroxymethylcytosine (5hmC) present in the sample; (e) detecting the complexes formed between 5hmC and the affinity reagent with secondary detection reagents; (f) quantifying 5hmC levels; and (g) identifying the patient as having cancer if the 5hmC levels in the sample are reduced as compared to a control.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: March 29, 2016
    Assignee: The Johns Hopkins University
    Inventors: Srinivasan Yegnasubramanian, Michael Christoph Haffner, Alcides Chaux, William G. Nelson, Angelo M. DeMarzo
  • Patent number: 9213466
    Abstract: A computer implemented method displays an object. The method includes causing the display of a context specific shortcut menu in response to a user command. The menu can include a set of functions relating to the context of the displayed object and a set of a predetermined number of the most recently used functions relating to the context of the displayed object. The most recently used functions can be displayed above the other functions.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: December 15, 2015
    Assignee: APPLE INC.
    Inventors: Clemens Homburg, Michael Christoph Haydn
  • Publication number: 20140038183
    Abstract: The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions useful for diagnosing or predicting cancer in a patient. In one embodiment, a method for identifying a patient as having cancer comprises the steps of (a) providing a formalin-fixed, paraffin-embedded or fresh frozen sample of patient tissue; (b) steaming the sample in antigen retrieval buffer; (c) incubating the sample in hydrochloric acid (HCl); (d) incubating the sample with an affinity reagent specific for 5hmC under conditions to form a complex between the affinity reagent and 5-hydroxymethylcytosine (5hmC) present in the sample; (e) detecting the complexes formed between 5hmC and the affinity reagent with secondary detection reagents; (f) quantifying 5hmC levels; and (g) identifying the patient as having cancer if the 5hmC levels in the sample are reduced as compared to a control.
    Type: Application
    Filed: August 1, 2013
    Publication date: February 6, 2014
    Applicant: The Johns Hopkins University
    Inventors: Srinivasan Yegnasubramanian, Michael Christoph Haffner, Alcides Chaux, William G. Nelson, Angelo M. DeMarzo
  • Publication number: 20110016425
    Abstract: A computer implemented method displays an object. The method includes causing the display of a context specific shortcut menu in response to a user command. The menu can include a set of functions relating to the context of the displayed object and a set of a predetermined number of the most recently used functions relating to the context of the displayed object. The most recently used functions can be displayed above the other functions.
    Type: Application
    Filed: July 20, 2009
    Publication date: January 20, 2011
    Applicant: Apple Inc.
    Inventors: Clemens Homburg, Michael Christoph Haydn
  • Patent number: 5479855
    Abstract: A belt-type printing machine, especially for a plurality of colors, comprising at least one printing station (2) containing a frame (1), idler rolls (7) arranged in bearings therein, an impression cylinder (6) for guiding a continuous web (8) to be printed arranged in preferably fixed bearings on the frame (1), a plate cylinder (3), two sprocket wheels (4, 5) coaxially mounted to but not commonly driven with the plate cylinder (3) and at least one tensioning cylinder (10), around which an endless belt (11) extends having at least one flexible printing plate and being provided with perforations for the sprocket wheels (4, 5), wherein an inking assembly (13) allocated to the flexible printing plate of the belt (11), a drive acting upon the sprocket wheels (4, 5) to the belt (11) and an additional single drive (32) acting upon the plate cylinder (3) to the belt (11) for the purpose of avoiding the jump movement between the perforations of the belt and the pins of the sprocket wheels are provided.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: January 2, 1996
    Assignee: Thimm Verpackung GmbH & Co.
    Inventors: Michael Christoph, Udo Welschlau, Wolfgang Becker