Patents by Inventor Michael Christopher Giano

Michael Christopher Giano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide hydrogels generating chemical exchange saturation transfer MRI contrast and uses thereof
    Patent number: 11235075
    Abstract: The present invention provides novel hydrogels through peptides, which are designed to self-assemble and produce magnetic resonance (MR) contrast through chemical exchange saturation transfer (CEST). The location and integrity of these gels could consequently be tracked using MR imaging. The self-assembly of the peptides into hydrogels can be brought about by a change in pH, ionic strength, temperature, and concentration of ions.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: February 1, 2022
    Assignees: THE JOHNS HOPKINS UNIVERSITY, KENNEDY KRIEGER INSTITUTE, INC., NATIONAL INSTITUTES OF HEALTH
    Inventors: Michael T. McMahon, Kannie Wai-Yan Chan, Michael Christopher Giano, Nikita Oskolkov, Joel Patrick Schneider, Xiaolei Song
  • NOVEL PEPTIDE HYDROGELS GENERATING CHEMICAL EXCHANGE SATURATION TRANSFER MRI CONTRAST AND USES THEREOF
    Publication number: 20160106871
    Abstract: The present invention provides novel hydrogels through peptides, which are designed to self-assemble and produce magnetic resonance (MR) contrast through chemical exchange saturation transfer (CEST). The location and integrity of these gels could consequently be tracked using MR imaging. The self-assembly of the peptides into hydrogels can be brought about by a change in pH, ionic strength, temperature, and concentration of ions.
    Type: Application
    Filed: April 28, 2014
    Publication date: April 21, 2016
    Applicants: The Johns Hopkins University, Kennedy Krieger Institute, Inc., National Institute of Health
    Inventors: Michael T. McMahon, Kannie Wai-Yan Chan, Michael Christopher Giano, Nikita Oskolkov, Joel Patrick Schneider, Xiaolei Song