Abstract: A wristband assembly according to the present disclosure includes a body including one or more chambers formed therein and a cap retainer disposed adjacent to the chamber opening. The assembly further includes a cap including a cap seat and a protrusion extending from the cap opposite the cap seat, where the cap seat interfaces with the cap retainer, and the cap seals the chamber from the environment. In at least one embodiment, a body is a flexible material. In at least one embodiment, the assembly includes multiple caps. In at least one embodiment, a cap includes a tab. In at least one embodiment, a cap includes a protrusion that is round. In at least one embodiment, a hinge attaches the cap to the body. In at least one embodiment, a cap protrusion may substantially conform or enclose a pill, tablet, blister packet, or other form of medication.

Abstract: A computer system (11, 12, 13) and method for managing data used in conducting clinical studies concerning subjects at a plurality of participating, geographically distributed clinical sites, each participating clinical site having a computer (17, 18, 19) for inputting, transmitting and receiving data over the Internet (15). An Internet network server computer (13) is interfaced to a database host computer (11) through a private network (12). The system (11, 12, 17, 18, 19) communicates data over the Internet (15, 16) to determine patient eligibility, randomization and initial prescriptions, which can then be adjusted by the physician online. The final prescription is printed out for signature and sent electronically to a distribution center (55). Study data is maintained in a database in the host computer (11) behind a firewall provided in the Internet server computer (13).

Abstract: A guidewire is provided for use with medical devices such as catheters. The guidewire has a structure which is particularly suitable for use as a micro-guidewire which is small enough for use even within the cerebral vascular system. The guidewire includes a unitary core wire of nickel and titanium alloy, which unitary core wire has a distal tip portion including a ribbon tip. A coil is positioned generally along the outside surface of the distal tip portion, including the ribbon tip. The distal tip portion of the device exhibits super-elasticity properties by which the tip is easily bent and rebent without kinking.