Abstract: A control system for a double-acting air cylinder of an agricultural implement includes a valve assembly configured to control a base end air pressure and a rod end air pressure of the double-acting air cylinder. The control system also includes a controller communicatively coupled to the valve assembly. The controller is configured to determine a target base end air pressure and a target rod end air pressure based on a target force of the double-acting air cylinder and a target damping factor of the double-acting air cylinder. The controller is also configured to control the valve assembly such that a first difference between the base end air pressure and the target base end air pressure is less than a first threshold value and a second difference between the rod end air pressure and the target rod end air pressure is less than a second threshold value.

Abstract: The invention provides compositions and methods for engineering self-attenuating circuitry in a cell that provides an optimal homeostasis between TGF-?/pSmad and Notch signaling to produce the long-term restoration of tissue regenerative potential and repair.

Abstract: The regenerative potential of aged stem cells is enhanced by activation of the Notch signaling pathway and/or inhibition of TGF-? signaling pathway. Stem cells in aged tissues are capable of proliferation and tissue regeneration, but in their native setting are not provided with the appropriate signals to do so. By administering tissue regenerating agents, organ stem/progenitor cells are provided with the appropriate signals to regenerate the corresponding differentiated tissues.