Abstract: The present invention in particular relates to a method of producing an immunogenic composition exhibiting reduced virucidal activity, as well as to the immunogenic composition and uses thereof, wherein the method in particular comprises the steps of: (a) providing a mixture with a first liquid and a recombinant protein, (b) concentrating the recombinant protein in the mixture by removing a portion of the first liquid from the mixture, and (c) processing the solution resulting from step (b) by continuous diafiltration.

Abstract: A device for releasing soft tissue includes a distractor and blade assembly. The distractor may include a guide channel positioned along an edge of the distractor and the blade assembly fits into the guide channel and is configured to slide within the channel of the distractor.

Abstract: Instruments, devices and methods for releasing soft tissue are disclosed. A tissue release instrument may include a distractor and blade assembly. The distractor may include a guide channel positioned along an edge of the distractor and wherein the blade assembly fits into the guide channel and is configured to slide within the channel of the distractor. Methods for assembling and using the instrument and devices to release soft tissue are also disclosed.

Abstract: The disclosed subject matter relates to Frequency Diversity Pulse Pair (FDPP) methods and technology implemented by, alternating the order of the pulse pair transmitted or order of the group of multiple pulses transmitted, the pulses differentiated based on the center frequency of each transmitted pulse. For example, where a pair of transmitted pulses have center frequencies f1 and f2, the pulses transmitted in pairs such that the first pair may be f1 followed by f2 and the second pair are a different order, such as f2 followed by f1.

Abstract: Systems, methods, and computer systems are disclosed for establishing a screen share session. One such method comprises a collaboration server receiving a message from an application executing on a mobile communication device. The message identifies that a voice call remote to the collaboration server has been initiated by the mobile communication device and established between a calling party using the mobile communication device and one or more called parties. The collaboration server determines that the calling party and the one or more called parties in the remote voice call have an active collaboration presence with the collaboration server. The collaboration server initiates a display of a screen share user interface control on a first computing device associated with the calling party and one or more second computing devices associated with the one or more called parties.

Abstract: Systems, methods, and computer systems are disclosed for establishing a screen share session. One such method comprises a collaboration server receiving a message from an application executing on a mobile communication device. The message identifies that a voice call remote to the collaboration server has been initiated by the mobile communication device and established between a calling party using the mobile communication device and one or more called parties. The collaboration server determines that the calling party and the one or more called parties in the remote voice call have an active collaboration presence with the collaboration server. The collaboration server initiates a display of a screen share user interface control on a first computing device associated with the calling party and one or more second computing devices associated with the one or more called parties.

Abstract: The disclosed subject matter relates to Frequency Diversity Pulse Pair (FDPP) methods and technology implemented by, alternating the order of the pulse pair transmitted or order of the group of multiple pulses transmitted, the pulses differentiated based on the center frequency of each transmitted pulse. For example, where a pair of transmitted pulses have center frequencies f1 and f2, the pulses transmitted in pairs such that the first pair may be f1 followed by f2 and the second pair are a different order, such as f2 followed by f1.

Abstract: A kit and associated method is for implanting a prosthetic device in a resected bone such as a humerus. The kit includes a trial assembly including a trial body portion having a trial bore defined therein, and a trial head portion having (i) a trail head member which includes a trial offset indicia, and (ii) an eccentrically located trial stem extending from the trial head member, the trial head stem being configured to be received within the trial bore. The kit also includes a final prosthesis assembly including a final body portion having a final bore defined therein, and a final head portion having (i) a final head member which includes a final offset indicia, and (ii) an eccentrically located final head stem extending from the final head portion, the final head stem being configured to be received within the final bore.

Abstract: Novel tricyclic compounds are disclosed having the general structure of Formulas I or II: were R1, R2 and R3 are defined in the written description of the invention. The compounds are useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by intracellular cytokine signaling.

Abstract: Novel pyridopyrimidine-based compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling.

Abstract: Novel pyridopyrimidine-based compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling.

Abstract: A kit and associated method is for implanting a prosthetic device in a resected bone such as a humerus. The kit includes a trial assembly including a trial body portion having a trial bore defined therein, and a trial head portion having (i) a trail head member which includes a trial offset indicia, and (ii) an eccentrically located trial stem extending from the trial head member, the trial head stem being configured to be received within the trial bore. The kit also includes a final prosthesis assembly including a final body portion having a final bore defined therein, and a final head portion having (i) a final head member which includes a final offset indicia, and (ii) an eccentrically located final head stem extending from the final head portion, the final head stem being configured to be received within the final bore.

Abstract: Novel pyridopyrimidine-based compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling.

Abstract: Novel tricyclic compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling.

Abstract: Novel tricyclic compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling. The compounds have the following formulas where R1, R2 and R3 are defined in the written description of the invention.

Abstract: Novel tricyclic compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling.

Abstract: A kit and associated method is disclosed for implanting a prosthetic device in a resected bone such as a humerus. The kit includes a trial assembly including a trial body portion having a trial bore defined therein, and a trial head portion having (i) a trail head member which includes a trial offset indicia, and (ii) an eccentrically located trial stem extending from the trial head member, the trial head stem being configured to be received within the trial bore. The kit also includes a final prosthesis assembly including a final body portion having a final bore defined therein, and a final head portion having (i) a final head member which includes a final offset indicia, and (ii) an eccentrically located final head stem extending from the final head portion, the final head stem being configured to be received within the final bore.

Abstract: A hand saw principally for use on sheet rock or gypsum wall board having a bi-partite handle and a thumb stop. The saw blade is provided with in-line teeth which cut on the forward and backward motion of the saw and which are provided with large cleanouts. The cutting teeth are also in line and the saw blade itself is thicker on the cutting surfaces than on the top. The arrangement permits a higher grade of premium steel to be used and the teeth can be readily sharpened. The saw may also have a blade that is sharpened on the top to a cutting edge resulting in an all purpose cutting instrument.