Abstract: This invention relates to methods for selecting a treatment, treating, and predicting survival time in subjects with cancer, such as colorectal cancer, based on tumor expression levels of chemokines, cytotoxic genes, and/or dendritic cell genes.

Abstract: A cam follower assembly includes a ball bearing having an outer ring and an inner assembly which includes two or more segments. The inner assembly is disposed in the outer ring with a full complement of balls disposed therebetween. The outer ring and inner assembly each include a race having a gothic arch cross sectional configuration that causes the balls to roll on two portions of each race.

Abstract: A bearing system for a rotating vertical shaft includes a first ball bearing, having a first pitch diameter and a first axial stiffness and a second ball bearing having a second pitch diameter and a second axial stiffness. The first ball bearing is a deep groove Conrad bearing. The second ball bearing is an angular contact bearing. The first and second ball bearings are coaxial, secured to one another and rotatable together. The first pitch diameter is at least 1.5 times greater than the second pitch diameter. The bearing system has an axial stiffness ratio defined by the first axial stiffness divided by the second axial stiffness. The axial stiffness ratio is based on an axial preload force applied to the second outer ring such that an operating torque of the bearing system is within a predetermined range at temperatures from minus 40 to positive 85 degrees Celsius.

Abstract: A cam follower for a ram of a metal can necker machine is provided. The cam follower has an outer ring and an inner ring coaxially disposed in the outer ring. A plurality of rolling elements is disposed in an annular cavity between the outer ring and the inner ring. The plurality of rolling elements is disposed between a first seal and a second seal. A shaft is received in a bore in the inner ring and is fixed relative thereto about the shaft axis. The outer ring is received in a tire. The tire has a thickness and a crown radius. The composition of the tire includes a metallic material, a plastic material, a non-metallic material, and combinations thereof.

Abstract: This invention relates to methods for treating subjects with breast cancer, based on tumor expression levels of chemokines.

Abstract: An apparatus for forming glass tubing is described. The apparatus for forming glass tubing comprises an endless former with an outer surface and an inner passage defining an inner surface. The apparatus for forming glass tubing further comprises two chambers from which molten glass may flow. One chamber flows molten glass to the outer surface of the endless former and another chamber flows molten glass to the inner surface of the endless former. The two flows of molten glass meet at the bottom of the former to form glass tubing.

Abstract: An apparatus for forming glass tubing is described. The apparatus for forming glass tubing comprises an endless former with an outer surface and an inner passage defining an inner surface. The apparatus for forming glass tubing further comprises two chambers from which molten glass may flow. One chamber flows molten glass to the outer surface of the endless former and another chamber flows molten glass to the inner surface of the endless former. The two flows of molten glass meet at the bottom of the former to form glass tubing.

Abstract: A bearing system for a rotating vertical shaft includes a first ball bearing, having a first pitch diameter and a first axial stiffness and a second ball bearing having a second pitch diameter and a second axial stiffness. The first ball bearing is a deep groove Conrad bearing. The second ball bearing is an angular contact bearing. The first and second ball bearings are coaxial, secured to one another and rotatable together. The first pitch diameter is at least 1.5 times greater than the second pitch diameter. The bearing system has an axial stiffness ratio defined by the first axial stiffness divided by the second axial stiffness. The axial stiffness ratio is based on an axial preload force applied to the second outer ring such that an operating torque of the bearing system is within a predetermined range at temperatures from minus 40 to positive 85 degrees Celsius.

Abstract: The present disclosure relates to atomizers for an aerosol delivery device such as a smoking article. The atomizer may include a liquid transport element and a wire continuously extending along a longitudinal length thereof. The wire may define end portions, contact portions, and a heating portion. The wire may be continuously wound about the liquid transport element such that each of the portions of the wire defines coils. A related input, cartridge, and method of forming atomizers also provided.

Abstract: A cam follower assembly includes a ball bearing having an outer ring and an inner assembly which includes two or more segments. The inner assembly is disposed in the outer ring with a full complement of balls disposed therebetween. The outer ring and inner assembly each include a race having a gothic arch cross sectional configuration that causes the balls to roll on two portions of each race.

Abstract: A switch for selectively coupling light from two input fibers to a selected two of plurality of output optical fibers. The switch was designed to handle standard Fiber optical connectors which have been polished and meet the specifications for the optical performance. The duplex mechanical switch creates a method to physically switch two fibers (Duplex) to another two fibers (Duplex). The performance regarding insertion losses, back reflection, crosstalk, immunity against backscattering of light and insensitivity to the wavelength of the light is consistent with this mechanical switch.

Abstract: A switch for selectively coupling light from two input fibers to a selected two of plurality of output optical fibers. The switch was designed to handle standard Fiber optical connectors which have been polished and meet the specifications for the optical performance. The duplex mechanical switch creates a method to physically switch two fibers (Duplex) to another two fibers (Duplex). The performance regarding insertion losses, back reflection, crosstalk, immunity against backscattering of light and insensitivity to the wavelength of the light is consistent with this mechanical switch.

Abstract: A switch for selectively coupling light from two input fibers to a selected two of plurality of output optical fibers. The switch was designed to handle standard Fiber optical connectors which have been polished and meet the specifications for the optical performance. The duplex mechanical switch creates a method to physically switch two fibers (Duplex) to another two fibers (Duplex). The performance regarding insertion losses, back reflection, crosstalk, immunity against backscattering of light and insensitivity to the wavelength of the light is consistent with this mechanical switch.

Abstract: The present invention relates to the technical field of providing corrosion resistant coatings or anticorrosion coatings on substrates which are susceptible to corrosion, particularly on metallic substrates, especially of providing chromate-free corrosion resistant (anticorrosion) coatings on such substrates.

Abstract: The present invention relates to a family of testis specific kinases (the tssk family), nucleic acid sequences encoding those kinases and antibodies against the kinases. The invention is further directed to the use of the tssk 4 kinase and other members of the tssk kinase family as targets for isolating specific inhibitors or antagonists of tssk kinase activity. Such inhibitors are anticipated to have use as contraceptive agents.

Abstract: A method and apparatus for positioning the terminal end surface of a cleaved optical fiber in a predetermined plane relative to a base fiber adapter which serves to interface the fiber surface with optical test equipment, or the like. The bare fiber adapter includes a pair of gripping members having opposed surfaces of resilient material movable into and out of engagement with an end portion of the fiber. A so-called connector module at the forward end of the adapter has an axial passageway for the fiber and is configured for releasable coupling to a fixture having a polished surface which serves as an abutment or stop for the end of the fiber when it is advanced through the passageway of the adapter connector module. Versatility is provided by releasable coupling of the connector modules to the gripping portion of the adapter, thereby permitting use of a variety of interchangeable connector modules configured for cooperative engagement with various types of test equipment and the like.