Patents by Inventor Michael Croft

Michael Croft has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating OX40 mediated recall immune responses and agents useful for identifying same
    Patent number: 7531170
    Abstract: T cell memory can persist in the absence of antigen. However, some memory cells by default are subject to signals accompanying periodic antigen exposure. OX40 is essential to the extent and persistence of Th2 memory when antigen is re-encountered. In an animal model of allergic asthma, inhibiting OX40/OX40L signaling during the secondary response to inhaled antigen suppressed lung inflammation. Inhibiting OX40 at the time of memory cell reactivation reduced the longevity of memory with further inflammation prevented upon tertiary encounter with antigen.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: May 12, 2009
    Assignee: La Jolla Institute for Allergy and Immunology
    Inventors: Michael Croft, Shahram Salek-Ardakani
  • Methods of treating OX40 medicated recall immune responses
    Patent number: 7291331
    Abstract: T cell memory can persist in the absence of antigen. However, some memory cells by default are subject to signals accompanying periodic antigen exposure. OX40 is essential to the extent and persistence of Th2 memory when antigen is re-encountered. In an animal model of allergic asthma, inhibiting OX40/OX40L signaling during the secondary response to inhaled antigen suppressed lung inflammation. Inhibiting OX40 at the time of memory cell reactivation reduced the longevity of memory with further inflammation prevented upon tertiary encounter with antigen.
    Type: Grant
    Filed: September 11, 2003
    Date of Patent: November 6, 2007
    Assignee: La Jolla Institute for Allergy and Immunology
    Inventors: Michael Croft, Shahram Salek-Ardakani
  • Galectins -1 and -4 in tumor development
    Publication number: 20070167405
    Abstract: Methods of prognosis and of prophylactic and therapeutic treatment of tumors based on the involvement of galectin-1 and galectin-4 in tumor development are described.
    Type: Application
    Filed: July 5, 2006
    Publication date: July 19, 2007
    Inventors: Margaret Huflejt, Valeri Mossine, Michael Croft
  • Method and system for minimizing the risk of leasing trucks
    Publication number: 20050171798
    Abstract: A method for reducing the risk of leasing class 8 trucks to individuals by making the truck seller guarantee a lessee for a particular truck for a predetermined period. The buyer then buys the truck from the seller and leases the truck to the lessee.
    Type: Application
    Filed: February 4, 2004
    Publication date: August 4, 2005
    Inventors: Michael Croft, Phillip Hofmann
  • Galectins -1 and -4 in tumor development
    Publication number: 20030109464
    Abstract: Methods of prognosis and of prophylactic and therapeutic treatment of tumors based on the involvement of galectin-1 and galectin-4 in tumor development are described.
    Type: Application
    Filed: September 30, 2002
    Publication date: June 12, 2003
    Inventors: Margaret E. Huflejt, Valeri V. Mossine, Michael Croft