Abstract: A power tool system includes a portable power tool having a housing, a motor with an output shaft in the housing, a tool holder secured on the output, and a data reader. The system also includes a power tool accessory configured to be retained by the tool holder that has a data storage device having data stored thereon. The data reader is configured to access the data stored on the data storage device when the power tool accessory is retained by the tool holder.

Abstract: An in-vehicle control system for communicating data between at least one of an office control system and a residential control system including a transceiver configured to be in communication with the office control system and the residential control system. The in-vehicle control system further including a memory device in communication with the transceiver. The memory device is configured to store a data file transmitted and/or received from the office control system and the residential control system.

Abstract: The present invention relates to processes and intermediates useful for the manufacture of spiroindolone compounds such as (1?R,3?S)-5,7?-dichloro-6?-fluoro-3?-methyl-2?,3?,4?,9?-tetrahydrospiro[indoline-3,1?-pyrido[3,4-b]indol]-2-one and salts and hydrates and solvates thereof.

Abstract: The present disclosure provides engineered transaminase polypeptides for the production of amines, polynucleotides encoding the engineered transaminases, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases to prepare compounds useful in the production of active pharmaceutical agents.

Abstract: The present disclosure provides engineered transaminase polypeptides for the production of amines, polynucleotides encoding the engineered transaminases, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases to prepare compounds useful in the production of active pharmaceutical agents.

Abstract: The present disclosure provides engineered transaminase polypeptides for the production of amines, polynucleotides encoding the engineered transaminases, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases to prepare compounds useful in the production of active pharmaceutical agents. The present disclosure provides engineered polypeptides having transaminase activity, polynucleotides encoding the polypeptides, methods of the making the polypeptides, and methods of using the polypeptides for the biocatalytic conversion of ketone substrates to amine products. The present enzymes have been engineered to have one or more residue differences as compared to the amino acid sequence of the naturally occurring transaminase of Vibrio fluvialis. In particular, the transaminases of the present disclosure have been engineered for efficient formation of chiral tryptamine derivatives from its corresponding prochiral ketone substrates.

Abstract: A mobile electronic communications device includes a housing, a memory, a data entry mechanism, a display for visual data, at least one wireless transceiver configured to transmit and receive electromagnetic signals conforming to a plurality of wireless signaling protocols, and a controller. The controller is communicatively connected to the memory, data entry mechanism, and display; and is configured to send and receive data using the at least one wireless transceiver.

Abstract: The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods of using the polypeptides.

Abstract: The present disclosure provides engineered transaminase polypeptides for the production of amines, polynucleotides encoding the engineered transaminases, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases to prepare compounds useful in the production of active pharmaceutical agents. The present disclosure provides engineered polypeptides having transaminase activity, polynucleotides encoding the polypeptides, methods of the making the polypeptides, and methods of using the polypeptides for the biocatalytic conversion of ketone substrates to amine products. The present enzymes have been engineered to have one or more residue differences as compared to the amino acid sequence of the naturally occurring transaminase of Vibrio fluvialis. In particular, the transaminases of the present disclosure have been engineered for efficient formation of chiral tryptamine derivatives from its corresponding prochiral ketone substrates.

Abstract: The present invention relates to processes and intermediates useful for the manufacture of spiroindolone compounds such as (1?R,3?S)-5,7?-dichloro-6?-fluoro-3?-methyl-2?,3?,4?,9?-tetrahydrospiro[indoline-3,1?-pyrido[3,4-b]indol]-2-one and salts and hydrates and solvates thereof.

Abstract: A mobile electronic communications device includes a housing, a memory, a data entry mechanism, a display for visual data, at least one wireless transceiver configured to transmit and receive electromagnetic signals conforming to a plurality of wireless signaling protocols, and a controller. The controller is communicatively connected to the memory, data entry mechanism, and display; and is configured to send and receive data using the at least one wireless transceiver.

Abstract: The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods of using the polypeptides.

Abstract: An in-vehicle control system for communicating data between at least one of an office control system and a residential control system including a transceiver configured to be in communication with the office control system and the residential control system. The in-vehicle control system further including a memory device in communication with the transceiver. The memory device is configured to store a data file transmitted and/or received from the office control system and the residential control system.

Abstract: A dynamic braking load analyzer that determines the proper resistance value for a dynamic braking load resistor to be used in combination with a variable frequency drive or servo-drive to accommodate the power dissipated from an induction motor when it is being reduced in speed. The analyzer includes a resistor bank having a plurality of resistors electrically coupled in parallel. Switches are provided between the resistors, and a resistor selector switch determines which resistors are switched into the resistor bank circuit. A heat sensing resistor in the resistor bank measures the heat generated by the resistors and provides a signal that is read by a heat meter. The combination of the temperature measurement and the resistance of the resistors in the circuit gives the proper braking resistance value for the deceleration of the induction motor.

Abstract: A tool for temporarily lifting and supporting reinforcing mesh above an underlying surface includes an elongate rod that can be held at a first end and which has a portion at a second end opposing the first end. The elongate rod, which can engage under an element of mesh, is mounted on a base member for turning on the underlying surface with a rotary movement of the elongate rod, so that movement of the elongate rod acts to lift the element of mesh.

Abstract: A dynamic braking load analyzer that determines the proper resistance value for a dynamic braking load resistor to be used in combination with a variable frequency drive or servo-drive to accommodate the power dissipated from an induction motor when it is being reduced in speed. The analyzer includes a resistor bank having a plurality of resistors electrically coupled in parallel. Switches are provided between the resistors, and a resistor selector switch determines which resistors are switched into the resistor bank circuit. A heat sensing resistor in the resistor bank measures the heat generated by the resistors and provides a signal that is read by a heat meter. The combination of the temperature measurement and the resistance of the resistors in the circuit gives the proper braking resistance value for the deceleration of the induction motor.

Abstract: A device for attaching at least three electrodes to a subject for stimulating abdominal muscles of the subject, comprising an attachment mechanism for extending around the torso of the subject and a main locating element provided on the attachment mechanism for locating a central electrode of the at least three electrodes adjacent the umbilicus of the subject. Two secondary locating elements are also provided on the attachment mechanism disposed on respective opposite sides of the main locating element for locating two corresponding side electrodes of the at least three electrodes spaced apart from the central electrode. Application of at least one pulsed signal to the subject through the respective central and side electrodes stimulates the abdominal muscles of the subject.

Abstract: A ranging and data taking system, useful as an acoustic sediment classification system. The system launches acoustic pulses into a water column above a sediment bed of interest (seafloor, riverbed, etc.) and records echoes from the pulses. The recorded echoes are transmitted to a processor, which uses the echoes to classify the sediment. Disposed between the hardware for data acquisition, and the processor, is S-RAM (static read only memory). This decouples data acquisition and data processing, which increases the speed of the system sufficiently that the system can display processed data, such as sediment contour plots, in virtual real time.