Patents by Inventor Michael Cucolo

Michael Cucolo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Complex of ras-farnesyltransferase inhibitor, a cyclodextrin, and ethanol
    Patent number: 7157446
    Abstract: A ras-farnesyltransferase inhibitor complex formed from a ras-farnesyltransferase inhibitor or a pharmaceutically acceptable salt thereof, a substituted cyclodextrin, and ethanol is provided. The complex has unexpectedly high aqueous solubility of the ras-farnesyltransferase inhibitor, improved dissolution, enhanced stability and is essentially free of particulate matter.
    Type: Grant
    Filed: April 20, 2004
    Date of Patent: January 2, 2007
    Assignee: Bristol Myers Squibb Company
    Inventors: Anne Marie Smith, Michael Cucolo, Munir N. Nassar
  • Complex of ras-farnesyltransferase inhibitor, a cyclodextrin, and ethanol
    Publication number: 20040235790
    Abstract: A ras-farnesyltransferase inhibitor complex formed from a ras-farnesyltransferase inhibitor or a pharmaceutically acceptable salt thereof, a substituted cyclodextrin, and ethanol is provided. The complex has unexpectedly high aqueous solubility of the ras-farnesyltransferase inhibitor, improved dissolution, enhanced stability and is essentially free of particulate matter.
    Type: Application
    Filed: April 20, 2004
    Publication date: November 25, 2004
    Inventors: Anne Marie Smith, Michael Cucolo, Munir N. Nassar