Patents by Inventor Michael Culler

Michael Culler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PARATHYROID HORMONE COMPOUNDS IN THE TREATMENT OF HYPOPARATHYROIDISM
    Publication number: 20250032590
    Abstract: The present technology generally relates to a method for management and/or treatment of hypoparathyroidism (HP) in a subject. The method comprises administering a dose of a PTH compound to the subject, wherein the PTH compound has an amino acid sequence as set forth in SEQ ID NO: 10; and wherein administration of the PTH compound maintains or improves bone integrity.
    Type: Application
    Filed: July 25, 2024
    Publication date: January 30, 2025
    Inventors: Michael Culler, Soraya Allas, Mark Sumeray, Thierry Abribat
  • Method of modulating the proliferation of medullary thyroid carcinoma cells
    Publication number: 20070259811
    Abstract: The present invention is directed to a method of decreasing the rate of proliferation of medullary thyroid carcinoma cells which comprises contacting medullary thyroid carcinoma cells with one or more SSTR2 agonist. A somatostatin receptor antagonist having the formula Cpa-cyclo(D-Cys-4-Pal-D-Trp-Lys-Thr-Cys)-Nal-NH2 is also disclosed.
    Type: Application
    Filed: May 2, 2007
    Publication date: November 8, 2007
    Inventors: Ettore Degli Uberti, Maria Zatelli, Michael Culler, David Coy
  • Somatostatin-dopamine chimeric analogs
    Publication number: 20060211607
    Abstract: Disclosed is a series of somatostatin-dopamine chimeric analogs which retain both somatostatin and dopamine activity in vivo.
    Type: Application
    Filed: May 15, 2006
    Publication date: September 21, 2006
    Inventors: Michael Culler, Zheng Dong, Sun Kim, Jacques-Pierre Moreau
  • Somatostatin analog and uses thereof
    Publication number: 20060069017
    Abstract: Claimed is a somatostatin agonist according to formula (I), D-Phe-c(Cys-Tyr(I)-D-Trp-Lys-Val-Cys)-Thr-NH2,??(I) or a pharmaceutically acceptable salt thereof, and uses thereof.
    Type: Application
    Filed: November 8, 2005
    Publication date: March 30, 2006
    Inventors: Thomas Gordon, Barry Morgan, Michael Culler
  • Somatostatin-dopamine chimeric analogs
    Publication number: 20060063704
    Abstract: The invention features somatostatin-dopamine chimeric analogs and methods relating to their therapeutic use for the treatment of neoplasia, acromegaly, and other conditions.
    Type: Application
    Filed: October 28, 2005
    Publication date: March 23, 2006
    Inventors: Zheng Dong, Michael Culler, Yeelena Shen
  • Method of inhibiting fibrosis with a somatostatin agonist
    Publication number: 20050222025
    Abstract: The present invention relates to a method of inhibiting fibrosis in a patient. The method comprises administering a therapeutically effective amount of a somatostatin, a somatostatin agonist or a pharmaceutically acceptable salt thereof to said patent.
    Type: Application
    Filed: September 7, 2004
    Publication date: October 6, 2005
    Inventors: Michael Culler, Philip Kasprzyk