Abstract: This present invention relates to BCMA binders (e.g. antibodies) and chimeric antigen receptor (CAR) constructs comprising a BCMA antigen binding molecule. The BCMA binders specifically bind to BCMA. The present BCMA CARs further comprise a hinge region (e.g., CD28 hinge), a transmembrane domain, and one or more intracellular NK cell signalling domains. NK cells expressing a BCMA CAR has increased efficacy in killing cancer cells. Provided herein also include therapeutic uses of the BCMA binders and BCMA CARs.

Abstract: A system for controlling the operation of an agricultural vehicle configured to tow an agricultural implement includes an engine coupled to a frame of the agricultural vehicle and a transmission operatively coupled to the engine. The system also includes a sensor configured to generate data indicative of a field surface incline forward of the agricultural vehicle relative to a direction of travel of the agricultural vehicle. Additionally, the system includes a computing system communicatively coupled to the sensor. The computing system is configured to determine a field surface incline parameter based on the data generated by the sensor. Furthermore, the computing system is configured to initiate an adjustment to an operation of at least one of the engine or the transmission based on the determined field surface parameter prior to engagement of the field surface incline.

Abstract: This present invention relates to BCMA binders (e.g. antibodies) and chimeric antigen receptor (CAR) constructs comprising a BCMA antigen binding molecule. The BCMA binders specifically bind to BCMA. The present BCMA CARs further comprise a hinge region (e.g., CD28 hinge), a transmembrane domain, and one or more intracellular NK cell signalling domains. NK cells expressing a BCMA CAR has increased efficacy in killing cancer cells. Provided herein also include therapeutic uses of the BCMA binders and BCMA CARs.

Abstract: A roof assembly for a work vehicle includes a roof panel having a vertical peak positioned longitudinally between a forward end and a rearward end of the roof panel. In addition, the roof panel includes a forward surface extending from the vertical peak to the forward end of the roof panel, and the roof panel includes a rearward surface extending from the vertical peak to the rearward end of the roof panel. The roof panel also includes a ridge extending around a periphery of the roof panel. The ridge has a first gap positioned at the rearward end of the roof panel, a second gap positioned at the forward end of the roof panel, and a third gap positioned at a first lateral end of the roof panel. In addition, the roof panel does not include a channel extending along the roof panel.

Abstract: The present application provides cord blood-derived natural killer (CB-NK) cells engineered to express chimeric receptors that target ADGRE2. Pharmaceutical compositions, kits and methods of treating cancer are also provided.

Abstract: A roof assembly for a work vehicle includes a grab rail and a grab rail support coupled to the grab rail. The grab rail support is configured to couple to a roof structure of the roof assembly, the grab rail support is configured to support the grab rail on the roof structure, the grab rail support has a hollow passage configured to facilitate passage of a wire, and the grab rail support has an inlet to the hollow passage configured to be positioned at an interior of the roof structure to enable the wire to extend from the interior of the roof structure into the hollow passage.

Abstract: A roof assembly for a work vehicle includes a roof panel having a vertical peak positioned longitudinally between a forward end and a rearward end of the roof panel. In addition, the roof panel includes a forward surface extending from the vertical peak to the forward end of the roof panel, and the roof panel includes a rearward surface extending from the vertical peak to the rearward end of the roof panel. The roof panel also includes a ridge extending around a periphery of the roof panel. The ridge has a first gap positioned at the rearward end of the roof panel, a second gap positioned at the forward end of the roof panel, and a third gap positioned at a first lateral end of the roof panel. In addition, the roof panel does not include a channel extending along the roof panel.

Abstract: A roof assembly for a work vehicle includes a grab rail and a grab rail support coupled to the grab rail. The grab rail support is configured to couple to a roof structure of the roof assembly, the grab rail support is configured to support the grab rail on the roof structure, the grab rail support has a hollow passage configured to facilitate passage of a wire, and the grab rail support has an inlet to the hollow passage configured to be positioned at an interior of the roof structure to enable the wire to extend from the interior of the roof structure into the hollow passage.

Abstract: A wear block assembly for a three-point hitch includes an actuator wedge that moves along a longitudinal axis relative to a lower lift arm of the three-point hitch. The actuator wedge also includes a tapered surface. The wear block assembly also includes a wear block that moves along a lateral axis relative to the lower lift arm and the wear block includes a wear surface that engages a sway block of the three-point hitch. The wear block also includes a contact surface that engages the tapered surface of the actuator wedge. The actuator wedge drives the wear block to move in a first direction along the lateral axis in response to movement of the actuator wedge in a second direction along the longitudinal axis.

Abstract: Encapsulated cure systems are provided wherein a curative is incorporated into a solid or semi-solid carrier material whereby mere fracturing or failure of the capsule wall encapsulating such cure systems will not provide for or allow sufficient release of the curative. Also provided are adhesive systems incorporating said encapsulated cure systems.

Abstract: The invention teaches continuous process for rapidly drying a population of pressure sensitive microcapsules.

Abstract: Encapsulated cure systems are provided wherein a curative is incorporated into a solid or semi-solid carrier material whereby mere fracturing or failure of the capsule wall encapsulating such cure systems will not provide for or allow sufficient release of the curative. Also provided are adhesive systems incorporating said encapsulated cure systems.

Abstract: Encapsulated cure systems are provided wherein a curative is incorporated into a solid or semi-solid carrier material whereby mere fracturing or failure of the capsule wall encapsulating such cure systems will not provide for or allow sufficient release of the curative. Also provided are adhesive systems incorporating said encapsulated cure systems.

Abstract: Surface insensitive, storage-stable, single-package liquid anaerobic adhesive and sealant compositions which are substantially free of amines, especially aromatic and tertiary amines, and imides, especially sulfimides such as saccharine and saccharine-type compounds.

Abstract: Stock packaging materials for manual and/or high speed industrial automated package formation and/or filing and closing applications having a curable pre-applied adhesive compositions applied to one or more seams or closure surfaces wherein the curative for the pre-applied adhesive composition is contained within a carrier which prevents its premature release.

Abstract: Stock materials for manual and/or high speed industrial automated bonding applications having a curable pre-applied adhesive or sealant compositions on the bonding surfaces wherein the curative for the pre-applied adhesive or sealant composition is contained within a carrier which prevents its premature release.

Abstract: Surface insensitive, storage-stable, single-package liquid anaerobic adhesive and sealant compositions which are substantially free of amines, especially aromatic and tertiary amines, and imides, especially sulfimides such as saccharine and saccharine-type compounds