Abstract: The present disclosure is directed to dual specific antibodies, which bind to both PD-L1 and PD-L2, and methods of using such antibodies to treat cancers, such as those that express or overexpress PD-L1, PD-L2, or both.

Abstract: The present disclosure is directed to dual specific antibodies, which bind to both PD-L1 and PD-L2, and methods of using such antibodies to treat cancers, such as those that express or overexpress PD-L1, PD-L2, or both.

Abstract: Disclosed herein are systems and methods for tracking and managing location information for automobile assets. By affixing passive transmitter tags with unique identification information to automobile assets, location information may be associated with designated areas and/or location information by scanning the passive transmitter tags at various scan points. The location and automobile asset information may be stored, read, and updated in a centralized cloud database platform, accessible at varying levels to suppliers, manufacturers, shippers, and others.

Abstract: Disclosed herein are systems and methods for tracking and managing location information for automobile assets. By affixing passive transmitter tags with unique identification information to automobile assets, location information may be associated with designated areas and/or location information by scanning the passive transmitter tags at various scan points. The location and automobile asset information may be stored, read, and updated in a centralized cloud database platform, accessible at varying levels to suppliers, manufacturers, shippers, and others.

Abstract: Disclosed herein are systems and methods for tracking and managing location information for automobile assets. By affixing passive transmitter tags with unique identification information to automobile assets, location information may be associated with designated areas and/or location information by scanning the passive transmitter tags at various scan points. The location and automobile asset information may be stored, read, and updated in a centralized cloud database platform, accessible at varying levels to suppliers, manufacturers, shippers, and others.

Abstract: Provided herein are methods of treating patients with a combination of a transcription inhibitor (e.g., a STAT3 inhibitor) and an immune checkpoint blockade therapy (e.g., anti-PD-1 therapy, anti-PD-L1 therapy, anti-CTLA-4 therapy). The patient may have a proliferative disease, such as cancer or psoriasis. The patient may have a pathogenic infection.

Abstract: A system that utilizes two different types of RFID data capture devices; at least one standard fixed RFID portal (e.g., one reader and two antennas) and at least one handheld or mobile RFID device in combination with passive RFID tags (i.e., transmitters). The system acquires, tracks, and reports asset location specific to a manufacturing plant and storage yard (i.e., the inventory), as well as production milestone events. GPS asset location data is tracked almost continuously and reported on demand.

Abstract: Disclosed herein are systems and methods for tracking and managing location information for automobile assets. By affixing passive transmitter tags with unique identification information to automobile assets, location information may be associated with designated areas and/or location information by scanning the passive transmitter tags at various scan points. The location and automobile asset information may be stored, read, and updated in a centralized cloud database platform, accessible at varying levels to suppliers, manufacturers, shippers, and others.

Abstract: A system that utilizes two different types of RFID data capture devices; at least one standard fixed RFID portal (e.g., one reader and two antennas) and at least one handheld or mobile RFID device in combination with passive RFID tags (i.e., transmitters). The system acquires, tracks, and reports asset location specific to a manufacturing plant and storage yard (i.e., the inventory), as well as production milestone events. GPS asset location data is tracked almost continuously and reported on demand.

Abstract: The present invention provides compositions and methods for effectuating the localized expression of anti-CTLA-4 antibody proximal to a target tissue in a patient.

Abstract: The present invention provides compositions and methods for effectuating the localized expression of anti-CTLA-4 antibody proximal to a target tissue in a patient.

Abstract: The present invention provides compositions and methods for effectuating the localized expression of anti-CTLA-4 antibody proximal to a target tissue in a patient.

Abstract: The present invention relates to a method and a device for pelletizing unprocessed cellulosic fibrous material on an industrial scale, and in particular to the use of said unprocessed cellulosic fibrous material pellets as a combustible fuel product.

Abstract: Airports and other public places require security measures for the screening of human subjects for illicit objects and materials concealed from view beneath clothing. However, at present most of such screening processes involve only metal detectors, which are inherently incapable of detecting non-metallic illicit objects and materials. For this reason, there remains a strong need for novel systems and methods that can detect all types of materials. The present invention provides for a portal detection system that is configured for safe, rapid, and non-invasive scanning of human subjects. For this purpose, the portal detection system utilizes acoustic technology to achieve this end. The portal detection systems of the present invention may optionally be used in conjunction with conventional metal detection means. The invention encompasses portal detection systems, their use in scanning human subjects, and corresponding methods of scanning human subjects for illicit objects and substances.

Abstract: Airports and other public places require security measures for the screening of human subjects for illicit objects and materials concealed from view beneath clothing. However, at present most of such screening processes involve only metal detectors, which are inherently incapable of detecting non-metallic illicit objects and materials. For this reason, there remains a strong need for novel systems and methods that can detect all types of materials. The present invention provides for a portal detection system that is configured for safe, rapid, and non-invasive scanning of human subjects. For this purpose, the portal detection system utilizes acoustic technology to achieve this end. The portal detection systems of the present invention may optionally be used in conjunction with conventional metal detection means. The invention encompasses portal detection systems, their use in scanning human subjects, and corresponding methods of scanning human subjects for illicit objects and substances.