Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers. The collapsible scaffold may include portions of differing radial stiffness based on location of the one or more impellers therein.

Abstract: Catheter blood pump that include an expandable pump portion extending distally from an elongate shaft. The pump portions include an expandable impeller housing including an expandable blood conduit that defines a blood lumen between an inflow and an outflow. The pump portions include one or more expandable impellers disposed at least partially within the blood lumen.

Abstract: Catheter blood pumps that include a sensor system. The pumps may include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pumps may also include one or more impellers. One or more sensors may be arranged with respect to inflow and outflow regions of the blood lumen, the scaffold and/or the impellers.

Abstract: Mowing systems include a mower and a remote control unit such as a handheld unit, between which is provided 1- or 2-way communications. Components and features are included in the mower, the remote control unit, or both to enhance the safety, functionality, or user experience of the system's user/operator. Aspects of the invention relate to: an enable switch on the remote control unit that requires activation within a specified time before activating a drive system or PTO unit; sharing diagnostic information between the mower and remote control unit and emitting user-detectable warnings in response to the shared information; reducing a danger level of the system when a proximity between the mower and the remote control unit is too small; and using inclinometers in the mower and the remote control unit to control operation of the mower based on tilt angles of both the mower and the remote control unit.

Abstract: Chromatography and synthesis columns, assemblies, components, and methods of assembly and disassembly are disclosed including a support assembly having lifting mechanisms in each of the legs to raise and lower a frame secured to the column, a swing arm and/or carriage guiding movement of a bottom plate of the column, a bolt-free coupling between the main tube and bottom plate of the column, and upper and lower slurry ports in the main tube of the column.

Abstract: A chromatography and synthesis column that includes a main tube, a plurality of lower media ports, and an internal groove. The internal groove is formed in an interior surface of the main tube and selectively provides an internal flow path between each of the internal lower media ports. This, in turn, facilitates quick and easy maintenance of the internal lower media ports and other components of the chromatography and synthesis column.

Abstract: Mowing systems include a remote control unit such as a handheld unit for use with a mower, between which is provided 1- or 2-way communications. Components and features are included in the mower, the remote control unit, or both to enhance the safety, functionality, or user experience of the system's user/operator. One aspect relates to a handheld unit having a logic-implemented safety interlock for a PTO switch and/or a speed switch to prevent such switches from becoming active simultaneously with an enablement command for the PTO unit and/or drive unit of the mower. Another aspect relates to incorporating an inclinometer and/or motion sensor such as an accelerometer into the handheld unit, and controlling operation of the mower based on outputs) from such sensor(s). Another aspect relates to providing a display or other visual indicator on the handheld unit, and displaying on the visual indicator an indication of a tilt angle of the mower.

Abstract: A single-use valve arrangement that includes a valve housing, a diaphragm carried by the valve housing, a pressure sensor, and a controller coupled to the pressure sensor. The valve housing defines an inlet and an outlet, the inlet adapted to be fluidly connected to an outlet of a virus removal filter. The diaphragm divides the valve housing into a first chamber and a second chamber fluidly isolated from the first chamber. The pressure sensor is configured to measure a pressure change in the second chamber due to movement of the diaphragm responsive to a pressure change in the first chamber. The controller is configured to determine an actual leak rate of the filter based on the measured pressure change, the controller further configured to determine the integrity of the filter by comparing the actual leak rate to an expected leak rate of the filter.

Abstract: An inline buffer dilution system is provided that includes a first flow control valve fluidly connected to a supply of diluent liquid, second and third flow control valves fluidly connected to supplies of a first buffer and a second buffer, respectively, and a mixing pump fluidly connected to the first, second, and third flow control valves and configured to mix an amount of the diluent liquid, the first buffer, and the second buffer to produce a diluted buffer solution. The system further includes a backpressure control valve configured to generate a backpressure that promotes mixing within the mixing pump, and a controller configured to control the backpressure based on the amount of the diluent liquid, the first buffer, and the second buffer being mixed in the mixing pump, such that the mixing pump yields a minimum mixing threshold across a range of fluid flows.

Abstract: A chromatography and synthesis column that includes a main tube, a plurality of lower media ports, and an internal groove. The internal groove is formed in an interior surface of the main tube and selectively provides an internal flow path between each of the internal lower media ports. This, in turn, facilitates quick and easy maintenance of the internal lower media ports and other components of the chromatography and synthesis column.

Abstract: Mowing systems include a mower and, optionally, a remote control unit such as a handheld unit, between which may be provided 1- or 2-way communications. Components and features are included in the mower, the remote control unit, or both to enhance the safety, functionality, or user experience of the system's user/operator. One aspect relates to monitoring a tilt angle of the mower, and defining or executing different system responses as a function of different first and second conditions that relate to the tilt angle. Another aspect relates to automatic adjustment of a speed setting of the mower's drive system as a function of a power takeoff (PTO) unit of the mower.

Abstract: Mowing systems include a mower and a remote control unit such as a handheld unit, between which is provided 1- or 2-way communications. Components and features are included in the mower, the remote control unit, or both to enhance the safety, functionality, or user experience of the system's user/operator. Aspects of the invention relate to: an enable switch on the remote control unit that requires activation within a specified time before activating a drive system or PTO unit; sharing diagnostic information between the mower and remote control unit and emitting user-detectable warnings in response to the shared information; reducing a danger level of the system when a proximity between the mower and the remote control unit is too small; and using inclinometers in the mower and the remote control unit to control operation of the mower based on tilt angles of both the mower and the remote control unit.

Abstract: Mowing systems include a mower and, optionally, a remote control unit such as a handheld unit, between which may be provided 1- or 2-way communications. Components and features are included in the mower, the remote control unit, or both to enhance the safety, functionality, or user experience of the system's user/operator. One aspect relates to monitoring a tilt angle of the mower, and defining or executing different system responses as a function of different first and second conditions that relate to the tilt angle. Another aspect relates to automatic adjustment of a speed setting of the mower's drive system as a function of a power takeoff (PTO) unit of the mower.

Abstract: Mowing systems include a mower and a remote control unit such as a handheld unit, between which is provided 1- or 2-way communications. Components and features are included in the mower, the remote control unit, or both to enhance the safety, functionality, or user experience of the system's user/operator. One aspect relates to an enable switch on the remote control unit that requires activation within a specified time before activating a drive system or PTO unit. Another aspect relates to sharing diagnostic information between the mower and remote control unit and emitting user-detectable warnings in response to the shared information. Another aspect relates to reducing a danger level of the system, e.g. disabling the PTO unit or slowing a drive speed transform function, when a proximity between the mower and the remote control unit is too small. Another aspect relates to controlling operation of the mower based on tilt angles of both the mower and the remote control unit.

Abstract: A chemical processing column that includes a column base and an assembly for maintaining plug flow in the column base. The column base is adapted to contain a bed of media. The assembly includes a sleeve removably coupled to the column base, a plate coupled to the plate, and a piston at least partially disposed within the sleeve. The assembly is dynamically movable relative to the column base to adjust a position of the piston relative to the column base to compensate for a change in volume occupied by the bed of media.

Abstract: An inline buffer dilution system is provided that includes a first flow control valve fluidly connected to a supply of diluent liquid, second and third flow control valves fluidly connected to supplies of a first buffer and a second buffer, respectively, and a mixing pump fluidly connected to the first, second, and third flow control valves and configured to mix an amount of the diluent liquid, the first buffer, and the second buffer to produce a diluted buffer solution. The system further includes a backpressure control valve configured to generate a backpressure that promotes mixing within the mixing pump, and a controller configured to control the backpressure based on the amount of the diluent liquid, the first buffer, and the second buffer being mixed in the mixing pump, such that the mixing pump yields a minimum mixing threshold across a range of fluid flows.

Abstract: Mowing systems include a remote control unit such as a handheld unit for use with a mower, between which is provided 1- or 2-way communications. Components and features are included in the mower, the remote control unit, or both to enhance the safety, functionality, or user experience of the system's user/operator. One aspect relates to a handheld unit having a logic-implemented safety interlock for a PTO switch and/or a speed switch to prevent such switches from becoming active simultaneously with an enablement command for the PTO unit and/or drive unit of the mower. Another aspect relates to incorporating an inclinometer and/or motion sensor such as an accelerometer into the handheld unit, and controlling operation of the mower based on outputs) from such sensor(s). Another aspect relates to providing a display or other visual indicator on the handheld unit, and displaying on the visual indicator an indication of a tilt angle of the mower.

Abstract: Mowing systems include a mower and, optionally, a remote control unit such as a handheld unit, between which may be provided 1- or 2-way communications. Components and features are included in the mower, the remote control unit, or both to enhance the safety, functionality, or user experience of the system's user/operator. One aspect relates to monitoring a tilt angle of the mower, and defining or executing different system responses as a function of different first and second conditions that relate to the tilt angle. Another aspect relates to automatic adjustment of a speed setting of the mower's drive system as a function of a power takeoff (PTO) unit of the mower.

Abstract: Mowing systems include a mower and a remote control unit such as a handheld unit, between which is provided 1- or 2-way communications. Components and features are included in the mower, the remote control unit, or both to enhance the safety, functionality, or user experience of the system's user/operator. One aspect relates to an enable switch on the remote control unit that requires activation within a specified time before activating a drive system or PTO unit. Another aspect relates to sharing diagnostic information between the mower and remote control unit and emitting user-detectable warnings in response to the shared information. Another aspect relates to reducing a danger level of the system, e.g. disabling the PTO unit or slowing a drive speed transform function, when a proximity between the mower and the remote control unit is too small. Another aspect relates to controlling operation of the mower based on tilt angles of both the mower and the remote control unit.