Patents by Inventor Michael D. Collini

Michael D. Collini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-Phenyl-1-[4(2-aminoethoxy)-benzyl]-indoles as estrogenic agents
    Publication number: 20040110824
    Abstract: The present invention relates to new 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole compounds which are useful as estrogenic agents, as well as pharmaceutical compositions and methods of treatment utilizing these compounds, which have the general structures below: 1
    Type: Application
    Filed: November 24, 2003
    Publication date: June 10, 2004
    Applicant: Wyeth
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Arthur A. Santilli
  • Phenyl benzisoxazoles as estrogenic agents
    Publication number: 20030207927
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure 1
    Type: Application
    Filed: December 11, 2002
    Publication date: November 6, 2003
    Applicant: Wyeth
    Inventors: Michael S. Malamas, Tam Q. Dinh, Iwan Gunawan, Michael D. Collini, Heather A. Harris, James C. Keith, Leo M. Albert
  • Substituted benzoxazoles as estrogenic agents
    Publication number: 20030199562
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure 1
    Type: Application
    Filed: December 4, 2002
    Publication date: October 23, 2003
    Applicant: Wyeth
    Inventors: Michael S. Malamas, Robert E. McDevitt, Iwan Gunawan, Eric S. Manas, Michael D. Collini, Heather A. Harris, James C. Keith, Leo M. Albert, C. Richard Lyttle
  • Substituted 2-phenyl benzofurans as estrogenic agents
    Publication number: 20030171428
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure 1
    Type: Application
    Filed: December 16, 2002
    Publication date: September 11, 2003
    Applicant: Wyeth
    Inventors: Christopher P. Miller, Michael D. Collini, David H. Kaufman, Robert L. Morris, Robert R. Singhaus, John W. Ullrich, Heather A. Harris, James C. Keith, Leo M. Albert, Rayomand J. Unwalla
  • 2-Phenyl-1-[4-(2-aminoethoxy)benzyl-indoles as estrogenic agents
    Publication number: 20030130274
    Abstract: The present invention relates to new 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole compounds which are useful as estrogenic agents, as well as pharmaceutical compositions and methods of treatment utilizing these compounds, which have the general structures below: 1
    Type: Application
    Filed: July 10, 2002
    Publication date: July 10, 2003
    Applicant: Wyeth
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Arthur A. Santilli
  • Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents
    Patent number: 6589980
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure wherein X, Y1, Y2, Y3, Y4, Z1, Z2, Z3, and Z4 are as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: July 8, 2003
    Assignee: Wyeth
    Inventors: Christopher P. Miller, Michael D. Collini, Heather A. Harris, James C. Keith, Jr.
  • Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents
    Publication number: 20030087955
    Abstract: This invention provides estrogen receptor modulators of formula 1, having the structure 1
    Type: Application
    Filed: May 15, 2002
    Publication date: May 8, 2003
    Applicant: Wyeth
    Inventors: Christopher P. Miller, Michael D. Collini, Heather A. Harris, James C. Keith
  • 5, 11-Dioxa-benzo[b]fluoren-10-one and 5-oxa-11-thia-benzo[b]fluoren-10-ones as estrogenic agents
    Patent number: 6559177
    Abstract: This invention provides estrogen receptor modulators of formula 1, having the structure wherein X, Y1, Y2, Y3, Y4, Z1, Z2, Z3, and Z4 are as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: May 6, 2003
    Assignee: Wyeth
    Inventors: Christopher P. Miller, Michael D. Collini, Heather A. Harris, James C. Keith, Jr.
  • Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1H-indol-5-ols
    Patent number: 6537971
    Abstract: This invention provides tissue selective estrogens of formula I having the structure wherein: R1 and R2 are independently, hydrogen, alkyl chain of 1-6 carbon atoms, benzyl, acyl of 2-7 carbon atoms, benzoyl, X is hydrogen, alkyl of 1-6 carbon atoms, CN, halogen, trifluoromethyl, or thioalkyl of 1-6 carbon atoms; n=1-3; with the proviso that at least one of R1 or R2 are not hydrogen, alkyl chain of 1-6 carbon atoms, benzyl, acyl of 2-7 carbon atoms, or benzoyl; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: March 25, 2003
    Assignee: Wyeth
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Anita Wai-Yin Chan, Arkadiy Z. Rubezhov
  • 5,11-dioxa-benzo[b]fluoren-10-one and 5-oxa-11-thia-benzo[b]fluoren-10-ones as estrogenic agents
    Publication number: 20020183310
    Abstract: This invention provides estrogen receptor modulators of formula 1, having the structure 1
    Type: Application
    Filed: April 15, 2002
    Publication date: December 5, 2002
    Applicant: Wyeth
    Inventors: Christopher P. Miller, Michael D. Collini, Heather A. Harris, James C. Keith
  • Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1H-indol-5-ols
    Publication number: 20020142971
    Abstract: This invention provides tissue selective estrogens of formula I having the structure 1
    Type: Application
    Filed: March 1, 2002
    Publication date: October 3, 2002
    Applicant: American Home Products Corporation
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Anita Wai-Yin Chan, Arkadiy Z. Rubezhov
  • Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1H-indol-5-ols
    Patent number: 6380166
    Abstract: This invention provides tissue selective estrogens of formula I having the structure wherein: R1 and R2 are independently, hydrogen, alkyl chain of 1-6 carbon atoms, benzyl, acyl of 2-7 carbon atoms, benzoyl, X is hydrogen, alkyl of 1-6 carbon atoms, CN, halogen, trifluoromethyl, or thioalkyl of 1-6 carbon atoms; n=1-3; with the proviso that at least one of R1 or R2 are not hydrogen, alkyl chain of 1-6 carbon atoms, benzyl, acyl of 2-7 carbon atoms, or benzoyl; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: April 30, 2002
    Assignee: American Home Products Corporation
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Anita Wai-Yin Chan, Arkadiy Z. Rubezhov
  • 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents
    Patent number: 6326367
    Abstract: The present invention relates to new 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole compounds which are useful as estrogenic agents, as well as pharmaceutical compositions and methods of treatment utilizing these compounds, which have the general structures below:
    Type: Grant
    Filed: September 2, 1999
    Date of Patent: December 4, 2001
    Assignee: American Home Products Corporation
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Arthur A. Santilli
  • 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents
    Patent number: 6291451
    Abstract: The present invention relates to new 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole compounds having the general structures below: which are useful in the treatment or inhibition of breast cancer.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: September 18, 2001
    Assignee: American Home Products Corporation
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Arthur A. Santilli
  • 2-phenyl-1- [4- (2-aminoethoxy) - benzyl] - indoles as estrogenic agents
    Publication number: 20010021719
    Abstract: The present invention relates to new 2-Phenyl-1-[(2-Aminoethoxy)-Benzyl]-Indole compounds which are usefuil as estrogenic agents, as well as pharmaceutical compositions and methods of treatment utiig these compounds, which have the general structures below: 1
    Type: Application
    Filed: February 8, 2001
    Publication date: September 13, 2001
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Arthur A. Santilli
  • PREGNANE GLUCURONIDES
    Publication number: 20010007859
    Abstract: This invention provides 5&agr;-pregnane-3,&bgr;,(20S), 21-triol, 20-O-&bgr;-glucuronide and 5&agr;-pregnane-3&bgr;,20R-diol, 20-O-&bgr;-glucuronide and pharmaceutically acceptable salts thereof which are useful as progestational agents.
    Type: Application
    Filed: October 8, 1999
    Publication date: July 12, 2001
    Inventors: CHRISTOPHER P. MILLER, BACH D. TRAN, MICHAEL D. COLLINI
  • Tissue selective compounds in the treatment of ovarian cancer
    Patent number: 6232307
    Abstract: The present invention relates to new 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole compounds which are useful as estrogenic agents, as well as pharmaceutical compositions and methods of treatment utilizing these compounds, which have the general structures below:
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: May 15, 2001
    Assignee: American Home Products Corporation
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Arthur A. Santilli
  • Tissue selective compounds in the treatment of prostate cancer or benign prostate hypertrophy
    Patent number: 6225308
    Abstract: The present invention relates to new 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole compounds which are useful as estrogenic agents, as well as pharmaceutical compositions and methods of treatment utilizing these compounds, which have the general structures below:
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: May 1, 2001
    Assignee: American Home Products Corporation
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Arthur A. Santilli
  • Tissue selective compounds in the treatment of endometrial proliferation
    Patent number: 6127404
    Abstract: The present invention relates to new 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indole compounds which are useful as estrogenic agents, as well as pharmaceutical compositions and methods of treatment utilizing these compounds, which have the general structures below: ##STR1##
    Type: Grant
    Filed: September 2, 1999
    Date of Patent: October 3, 2000
    Assignee: American Home Products Corporation
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran, Arthur A. Santilli
  • Indenoindoles and benzocarbazoles as estrogenic agents
    Patent number: 6107292
    Abstract: The present invention relates to new substituted benzo[a]carbazoles and indenoindoles which are useful as estrogenic agents, as well as pharmaceutical compositions and methods of treatment utilizing these compounds, having the general structures below.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: August 22, 2000
    Assignee: American Home Products Corporation
    Inventors: Chris P. Miller, Michael D. Collini, Bach D. Tran