Patents by Inventor Michael D. Dake

Michael D. Dake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200163751
    Abstract: A device for treating disease along a main vessel and at least one branch vessel extending from the main vessel includes a branch member for deployment in the branch vessel, the branch member having a branch lumen; and a main body for deployment in the main vessel. The main body has a generally tubular wall extending generally longitudinally between opposite first and second ends. The wall has an internal surface defining a main lumen and an opposite outer surface. The wall has a recessed portion that is recessed relative to the outer surface of the wall and positioned between the first and second ends of the main body. The main body has an opening formed in the recessed portion of the wall for receiving the branch member therethrough such that the branch lumen is in fluid communication with the main lumen.
    Type: Application
    Filed: January 28, 2020
    Publication date: May 28, 2020
    Inventors: Michael D. Dake, Joshua J. Lovekamp, Michael C. Nilson, Edward E. Shaw
  • Publication number: 20200101097
    Abstract: Compositions and methods are provided that are useful for the delivery, including transdermal delivery, of biologically active agents, such as non-protein non-nucleotide therapeutics and protein-based therapeutics excluding insulin, botulinum toxins, antibody fragments, and VEGF. The compositions and methods are particularly useful for topical delivery of antifungal agents and antigenic agents suitable for immunization. Alternatively, the composition can be prepared with components useful for targeting the delivery of the compositions as well as imaging components.
    Type: Application
    Filed: January 7, 2019
    Publication date: April 2, 2020
    Inventors: Michael D. Dake, Jacob M. Waugh
  • Patent number: 10588735
    Abstract: A device for treating disease along a main vessel and at least one branch vessel extending from the main vessel includes a branch member for deployment in the branch vessel, the branch member having a branch lumen; and a main body for deployment in the main vessel. The main body has a generally tubular wall extending generally longitudinally between opposite first and second ends. The wall has an internal surface defining a main lumen and an opposite outer surface. The wall has a recessed portion that is recessed relative to the outer surface of the wall and positioned between the first and second ends of the main body. The main body has an opening formed in the recessed portion of the wall for receiving the branch member therethrough such that the branch lumen is in fluid communication with the main lumen.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: March 17, 2020
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Michael D. Dake, Joshua J. Lovekamp, Michael C. Nilson, Edward E. Shaw
  • Publication number: 20190247293
    Abstract: Improved formulations for transdermal delivery of botulinum toxin are disclosed. The formulations include, for example, botulinum toxin non-covalently associated with a positively charged backbone having branching or efficiency groups. The formulations also include a partitioning agent, oligo-bridge, or polyanion bridge, and may optionally contain a viscosity modifying agent. The formulations are designed for topical application onto the skin of a patient and may be used to treat wrinkles, hyperhidrosis, and other health-related problems. Kits for administration are also described.
    Type: Application
    Filed: September 24, 2018
    Publication date: August 15, 2019
    Inventors: Michael D Dake, Jacob M Waugh
  • Publication number: 20190105261
    Abstract: Compositions for topical delivery of an active agent and methods for using such compositions are described herein. Compositions include one or more active agents and about 0.001 wt. % to about 10 wt. % of a extracellular matrix component having average molecular weight of about 2,000 daltons to about 20,000 daltons. The extracellular components include hyaluronic acid, collagen, fibronectin, elastin, lectin, and fragments thereof and combinations thereof.
    Type: Application
    Filed: October 11, 2018
    Publication date: April 11, 2019
    Inventors: Jacob M. WAUGH, Michael D. DAKE
  • Patent number: 10172877
    Abstract: Compositions and methods are provided that are useful for the delivery, including transdermal delivery, of biologically active agents, such as non-protein non-nucleotide therapeutics and protein-based therapeutics excluding insulin, botulinum toxins, antibody fragments, and VEGF. The compositions and methods are particularly useful for topical delivery of antifungal agents and antigenic agents suitable for immunization. Alternatively, the composition can be prepared with components useful for targeting the delivery of the compositions as well as imaging components.
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: January 8, 2019
    Assignee: REVANCE THERAPEUTICS, INC.
    Inventors: Michael D. Dake, Jacob M. Waugh
  • Patent number: 10080786
    Abstract: Improved formulations for transdermal delivery of botulinum toxin are disclosed. The formulations include, for example, botulinum toxin non-covalently associated with a positively charged backbone having branching or efficiency groups. The formulations also include a partitioning agent, oligo-bridge, or polyanion bridge, and may optionally contain a viscosity modifying agent. The formulations are designed for topical application onto the skin of a patient and may be used to treat wrinkles, hyperhidrosis, and other health-related problems. Kits for administration are also described.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: September 25, 2018
    Assignee: REVANCE THERAPEUTICS, INC.
    Inventors: Michael D Dake, Jacob M Waugh
  • Publication number: 20160317174
    Abstract: The present invention relates to methods of using medical cutting tools for treating aortic septal dissections.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Inventor: Michael D. Dake
  • Patent number: 9387039
    Abstract: The present invention relates to methods of using medical cutting tools for treating aortic septal dissections.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: July 12, 2016
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Cody L. Bliss, Edward H. Cully, Michael D. Dake, Joel M. Greene, Joshua J. Lovekamp, Michael C. Nilson, Himanshu J. Patel, David M. Williams, William P. Witort
  • Publication number: 20160193032
    Abstract: A device for treating disease along a main vessel and at least one branch vessel extending from the main vessel includes a branch member for deployment in the branch vessel, the branch member having a branch lumen; and a main body for deployment in the main vessel. The main body has a generally tubular wall extending generally longitudinally between opposite first and second ends. The wall has an internal surface defining a main lumen and an opposite outer surface. The wall has a recessed portion that is recessed relative to the outer surface of the wall and positioned between the first and second ends of the main body. The main body has an opening formed in the recessed portion of the wall for receiving the branch member therethrough such that the branch lumen is in fluid communication with the main lumen.
    Type: Application
    Filed: March 16, 2016
    Publication date: July 7, 2016
    Inventors: Michael D. Dake, Joshua J. Lovekamp, Michael C. Nilson, Edward E. Shaw
  • Publication number: 20160114014
    Abstract: A composition for topical application of a botulinum toxin (including botulinum toxin derivatives) comprises a botulinum toxin and a carrier comprising a polymeric backbone comprising a long-chain polypeptide or nonpeptidyl polymer having attached positively charged branching or “efficiency” groups. The invention also relates to methods for reducing muscle paralysis and other conditions that may be treated with a botulinum toxin, particularly paralysis of subcutaneous, and most particularly, facial, muscles, by topically applying an effective amount of the botulinum toxin and carrier, in conjunction, to the subject's skin or epithelium. Kits for administration are also described.
    Type: Application
    Filed: December 10, 2015
    Publication date: April 28, 2016
    Inventors: Michael D. Dake, Jacob M. Waugh
  • Patent number: 9314416
    Abstract: Improved formulations for transdermal delivery of botulinum toxin are disclosed. The formulations include, for example, botulinum toxin non-covalently associated with a positively charged backbone having branching or efficiency groups. The formulations also include a partitioning agent, oligo-bridge, or polyanion bridge, and may optionally contain a viscosity modifying agent. The formulations are designed for topical application onto the skin of a patient and may be used to treat wrinkles, hyperhidrosis, and other health-related problems. Kits for administration are also described.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: April 19, 2016
    Assignee: Revance Therapeutics, Inc.
    Inventors: Michael D. Dake, Jacob M. Waugh
  • Patent number: 9314328
    Abstract: A device for treating disease along a main vessel and at least one branch vessel extending from the main vessel includes a branch member for deployment in the branch vessel, the branch member having a branch lumen; and a main body for deployment in the main vessel. The main body has a generally tubular wall extending generally longitudinally between opposite first and second ends. The wall has an internal surface defining a main lumen and an opposite outer surface. The wall has a recessed portion that is recessed relative to the outer surface of the wall and positioned between the first and second ends of the main body. The main body has an opening formed in the recessed portion of the wall for receiving the branch member therethrough such that the branch lumen is in fluid communication with the main lumen.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: April 19, 2016
    Assignee: W. L. GORE & ASSOCIATES, INC.
    Inventors: Michael D. Dake, Joshua J. Lovekamp, Michael C. Nilson, Edward E. Shaw
  • Publication number: 20160051646
    Abstract: Improved formulations for transdermal delivery of botulinum toxin are disclosed. The formulations include, for example, botulinum toxin non-covalently associated with a positively charged backbone having branching or efficiency groups. The formulations also include a partitioning agent, oligo-bridge, or polyanion bridge, and may optionally contain a viscosity modifying agent. The formulations are designed for topical application onto the skin of a patient and may be used to treat wrinkles, hyperhidrosis, and other health-related problems. Kits for administration are also described.
    Type: Application
    Filed: November 9, 2015
    Publication date: February 25, 2016
    Inventors: Michael D. Dake, Jacob M. Waugh
  • Patent number: 9211248
    Abstract: A composition for topical application of a botulinum toxin (including botulinum toxin derivatives) comprises a botulinum toxin and a carrier comprising a polymeric backbone comprising a long-chain polypeptide or nonpeptidyl polymer having attached positively charged branching or “efficiency” groups. The invention also relates to methods for reducing muscle paralysis and other conditions that may be treated with a botulinum toxin, particularly paralysis of subcutaneous, and most particularly, facial, muscles, by topically applying an effective amount of the botulinum toxin and carrier, in conjunction, to the subject's skin or epithelium. Kits for administration are also described.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: December 15, 2015
    Assignee: Revance Therapeutics, Inc.
    Inventors: Michael D. Dake, Jacob M. Waugh
  • Publication number: 20150320781
    Abstract: Compositions and methods are provided that are useful for the delivery, including transdermal delivery, of biologically active agents, such as non-protein non-nucleotide therapeutics and protein-based therapeutics excluding insulin, botulinum toxins, antibody fragments, and VEGF. The compositions and methods are particularly useful for topical delivery of antifungal agents and antigenic agents suitable for immunization. Alternatively, the composition can be prepared with components useful for targeting the delivery of the compositions as well as imaging components.
    Type: Application
    Filed: March 9, 2015
    Publication date: November 12, 2015
    Applicant: REVANCE THERAPEUTICS, INC.
    Inventors: Michael D. Dake, Jacob M. Waugh
  • Patent number: 9180081
    Abstract: Improved formulations for transdermal delivery of botulinum toxin are disclosed. The formulations include, for example, botulinum toxin non-covalently associated with a positively charged backbone having branching or efficiency groups. The formulations also include a partitioning agent, oligo-bridge, or polyanion bridge, and may optionally contain a viscosity modifying agent. The formulations are designed for topical application onto the skin of a patient and may be used to treat wrinkles, hyperhidrosis, and other health-related problems. Kits for administration are also described.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: November 10, 2015
    Assignee: REVANCE THERAPEUTICS, INC.
    Inventors: Michael D. Dake, Jacob M. Waugh
  • Publication number: 20150313626
    Abstract: The present invention relates to methods of using medical cutting tools for treating aortic septal dissections.
    Type: Application
    Filed: July 13, 2015
    Publication date: November 5, 2015
    Inventors: Cody L. Bliss, Edward H. Cully, Michael D. Dake, Joel M. Greene, Joshua J. Lovekamp, Michael C. Nilson, Himanshu J. Patel, David M. Williams, William P. Witort
  • Patent number: 9107681
    Abstract: The present invention relates to methods of using medical cutting tools for treating aortic septal dissections.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: August 18, 2015
    Assignee: W. L. Gore Associates, Inc.
    Inventors: Cody L. Bliss, Edward H. Cully, Michael D. Dake, Joel M. Greene, Joshua J. Lovekamp, Michael C. Nilson, Himanshu J. Patel, David M. Williams, William P. Witort
  • Publication number: 20150196593
    Abstract: Methods of altering properties of tissues, by providing an effective modifying amount of zinc, which may be in the form of zinc ions. This is accomplished through the use of topical compositions containing one or more zinc-containing components such as salts and/or other zinc compounds or complexes, particularly zinc acetate. Altering properties of tissues includes increasing or decreasing fatty tissue, increasing or decreasing epidermal thickness, increasing elastin content, and preventing or treating gum regression or atrophy. Also disclosed is the provision of a contact lens coated with a zinc-containing material, to improve vision by increasing elastin content of the lens of the eye through release of zinc ions.
    Type: Application
    Filed: January 23, 2015
    Publication date: July 16, 2015
    Inventors: Pamela Cifra, Michael D. Dake, Christopher Elkins, Jacob M. Waugh