Patents by Inventor Michael D. Gershon

Michael D. Gershon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH ALTERED SERT ACTIVITY
    Publication number: 20170071928
    Abstract: The present invention provides, inter alia, methods for treating or ameliorating the effects of a disease associated with altered serotonin transporter molecule (SERT) activity in a subject in need thereof. The methods include administering to the subject an effective amount of a 5-HT4 agonist or a pharmaceutically acceptable salt thereof. Pharmaceutical compositions and kits for the same are also provided. The present invention additionally provides methods for treating or ameliorating the effects of elevated serotonin transporter molecule activity in the gastrointestinal tract of a subject in need thereof and a gastrointestinal abnormality associated with autism spectrum disorder in a subject in need thereof.
    Type: Application
    Filed: May 15, 2015
    Publication date: March 16, 2017
    Inventors: Michael D. Gershon, Kara Gross Margolis
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF NECROTIZING ENTEROCOLITIS
    Publication number: 20130303763
    Abstract: This invention relates to tryptophan hydroxylase inhibitors, compositions comprising them, and methods of their use for the treatment, management and/or prevention of necrotizing enterocolitis.
    Type: Application
    Filed: March 28, 2013
    Publication date: November 14, 2013
    Inventors: Michael D. GERSHON, Kara Gross MARGOLIS
  • Genetically engineered cell lines and systems for propagating varicella zoster virus and methods of use thereof
    Publication number: 20080279888
    Abstract: The present invention provides genetically engineered cell lines, recombinant vectors, and vaccines. The present invention also provides methods for generating an in vitro system for Varicella zoster virus (VZV), and the in vitro systems generated by these methods. The present invention further provides methods for reactivating VZV, and VZV reactivated by these methods. Finally, the present invention provides a method of screening for an agent for treating VZV infection.
    Type: Application
    Filed: September 24, 2007
    Publication date: November 13, 2008
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Michael D. Gershon, Zhenglun Zhu, Saul Silverstein, Anne A. Gershon
  • Genetically engineered cell lines and systems for propagating virus and methods of use thereof
    Patent number: 7273616
    Abstract: The present invention provides genetically engineered cell lines, recombinant vectors, and vaccines. The present invention also provides methods for generating an in vitro system for Varicella zoster virus (VZV), and the in vitro systems generated by these methods. The present invention further provides methods for reactivating VZV, and VZV reactivated by these methods. Finally, the present invention provides a method of screening for an agent for treating VZV infection.
    Type: Grant
    Filed: May 12, 2003
    Date of Patent: September 25, 2007
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Jason J. Chen, Anne A. Gershon, Zhenglun Zhu, Saul Silverstein, Michael D. Gershon