Patents by Inventor Michael D. Hack

Michael D. Hack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLAP MODULATORS
    Publication number: 20140221311
    Abstract: The present invention relates to compounds of Formula (I), or a form thereof, wherein ring A, R1, R2, R3, R3?, L, W, and V are as defined herein, useful as FLAP modulators. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I).
    Type: Application
    Filed: January 31, 2014
    Publication date: August 7, 2014
    Applicant: JANSSEN PHARMACEUTICA NV
    Inventors: Genesis M. Bacani, Wendy Eccles, Anne E. Fitzgerald, Steven D. Goldberg, Michael D. Hack, Natalie A. Hawryluk, William M. Jones, John M. Keith, Paul Krawczuk, Alec D. Lebsack, Alice Lee-Dutra, Jing Liu, Kelly J. McClure, Steven P. Meduna, Daniel J. Pippel, Mark D. Rosen, Zachary S. Sales
  • FLAP MODULATORS
    Publication number: 20140221310
    Abstract: The present invention relates to compounds of Formula (I), or a form thereof, wherein ring A, R1, L and R2 are as defined herein, useful as FLAP modulators. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.
    Type: Application
    Filed: January 31, 2014
    Publication date: August 7, 2014
    Applicant: JANSSEN PHARMACEUTICA NV
    Inventors: Wendy Eccles, Anne E. Fitzgerald, Michael D. Hack, Natalie A. Hawryluk, William M. Jones, John M. Keith, Paul Krawczuk, Alec D. Lebsack, Jing Liu, Neelakandha S. Mani, Kelly J. McClure, Steven P. Meduna, Mark D. Rosen
  • TETRAHYDRO-PYRIMIDOAZEPINES AS MODULATORS OF TRPV1
    Publication number: 20140135311
    Abstract: Certain tetrahydro-pyrimidoazepine compounds are described, which are useful as TRPV1 modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by TRPV1. Thus, the compounds may be administered to treat, e.g., pain, itch, cough, asthma, or inflammatory bowel disease.
    Type: Application
    Filed: January 17, 2014
    Publication date: May 15, 2014
    Applicant: Janssen Pharmaceutica NV
    Inventors: Brett D. Allison, Bryan James Branstetter, J. Guy Breitenbucher, Michael D. Hack, Natalie A. Hawryluk, Alec D. Lebsack, Kelly J. McClure, Jeffrey E. Merit
  • Bicyclic pyrazole compounds as antibacterial agents
    Patent number: 8242275
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: August 14, 2012
    Assignee: Janssen Pharmaceutica NV
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Brian J. Morrow, S. Timothy Motley, Alejandro Santillan, Jr., Karen J. Shaw, Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J. M. Wiener
  • Bicyclic pyrazole compounds as antibacterial agents
    Patent number: 8232391
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: July 31, 2012
    Assignee: Janssen Pharmaceutica NV
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Brian J. Morrow, S. Timothy Motley, Alejandro Santillan, Jr., Karen J. Shaw, Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J. M. Wiener
  • Bicyclic pyrazole compounds as antibacterial agents
    Patent number: 7842810
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: November 30, 2010
    Assignee: Janssen Pharmaceutica, NV
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Alejandro Santillan, Jr., Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J. M. Wiener
  • BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS
    Publication number: 20100280240
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Application
    Filed: July 9, 2010
    Publication date: November 4, 2010
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Brain J. Morrow, S. Timothy Motley, Alejandro Santillan, JR., Karen J. Shaw, Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J.M. Wiener
  • BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS
    Publication number: 20100274005
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Application
    Filed: July 9, 2010
    Publication date: October 28, 2010
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Brian J. Morrow, S. Timothy Motley, Alejandro Santillan, JR., Karen J. Shaw, Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J. M. Wiener
  • BICYCLIC PIRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS
    Publication number: 20100274004
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Application
    Filed: July 9, 2010
    Publication date: October 28, 2010
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Brian J. Morrow, S. Timothy Motley, Alejandro Santillan, JR., Karen J. Shaw, Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J.M. Wiener
  • Benzoimidazole compounds
    Patent number: 7723359
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: May 25, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: James P. Edwards, Michael D. Hack, David E. Kindrachuk, Jennifer D. Venable
  • Benzoimidazole compounds
    Patent number: 7723526
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: May 25, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: James P. Edwards, Michael D. Hack, David E. Kindrachuk, Jennifer D. Venable
  • Benzoimidazole compounds
    Patent number: 7723527
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: May 25, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Kristen L. Arienti, James G. Breitenbucher, Daniel J. Buzard, James P. Edwards, Michael D. Hack, Alice Lee-Dutra
  • Benzoimidazole compounds
    Patent number: 7705143
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: April 27, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Daniel J. Buzard, Michael D. Hack
  • Benzoimidazole compounds
    Patent number: 7705149
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: April 27, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: James P. Edwards, Michael D. Hack, David E. Kindrachuk, Jennifer D. Venable
  • Benzoimidazole compounds
    Patent number: 7662966
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: February 16, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: James P. Edwards, Michael D. Hack, David E. Kindrachuk, Jennifer D. Venable
  • Benzoimidazole compounds
    Publication number: 20090281307
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Application
    Filed: August 26, 2008
    Publication date: November 12, 2009
    Inventors: Kristen L. Arienti, James G. Breitenbucher, Daniel J. Buzard, James P. Edwards, Michael D. Hack, Alice Lee-Dutra, Haripada Khatuya
  • Benzoimidazole compounds
    Publication number: 20090275748
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Application
    Filed: August 26, 2008
    Publication date: November 5, 2009
    Inventors: James P. Edwards, Michael D. Hack, David E. Kindrachuk, Jennifer D. Venable
  • Benzoimidazole compounds
    Publication number: 20090270366
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Application
    Filed: August 26, 2008
    Publication date: October 29, 2009
    Inventors: James P. Edwards, Michael D. Hack, David E. Kindrachuk, Jennifer D. Venable
  • Benzoimidazole compounds
    Publication number: 20090270611
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Application
    Filed: August 26, 2008
    Publication date: October 29, 2009
    Inventors: James P. Edwards, Michael D. Hack, David E. Kindrachuk, Jennifer D. Venable
  • Benzoimidazole compounds
    Publication number: 20090270613
    Abstract: Benzoimidazole compounds, compositions, and methods of using them in leukocyte recruitment inhibition, in modulating H4 receptor, and in treating conditions such as inflammation, H4 receptor-mediated conditions, and related conditions.
    Type: Application
    Filed: August 26, 2008
    Publication date: October 29, 2009
    Inventors: James P. Edwards, Michael D. Hack, David E. Kindrachuk, Jennifer D. Venable